research centers


Search results: Found 74

Listing 1 - 10 of 74 << page
of 8
>>
Sort by

Article
Prevalence of Fibromyalgia in Iraqi Patients with Ischemic Heart Disease

Authors: Ziad S.Al-Rawi* DPM --- Faiq I. Gorial** CABM, FIBMS --- Khudhir M. Al-Bidri* FIBMS (Int. Med), FIBMS
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2009 Volume: 51 Issue: 2 Pages: 127-129
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Fibromyalgia has been associated with physical and emotional trauma including invasive medical procedures. Both Fibromyalgia and ischemic heart disease have been linked with depression. The aim of the study is to assess the prevalence of fibromyalgia syndrome in patients with ischemic heart disease.Patients and Methods: A cross-sectional comparative study was done in the Iraqi Center for Heart Disease. One hundred patients, angiographically proved to have ischemic heart disease, were subjected to rheumatologic examination by another physician, and compared to hundred healthy individuals as a control group. Diagnosis of fibromyalgia was based on 1990 American College of Rheumatology Classification criteria for the diagnosis of fibromyalgia.Results: Eighteen (18%) patients with ischemic heart disease fulfilled the American College of Rheumatology criteria for fibromyalgia syndrome in comparison to only 6(6%) of the controls, and this difference is statistically significant (P-value = 0.009).There were statistical significant effects of gender, age, and number of coronary vessels on the prevalence of fibromyalgia syndrome. Conclusion: fibromyalgia occurs with high frequency (18%) in patients with ischemic heart disease.


Article
Is any Relation between Cytogenetic types of Down's Syndrome and Congenital Heart Disease
هل هنالك علاقة بين الفحص الوراثي (الكروموسومي) لمتلازمة داون وتشوهات القلب الوراثية

Author: Sabeeha Al-Mefraji د. صبيجة المفرجي
Journal: IRAQI JOURNALOF COMMUNITY MEDICINE المجلة العراقية لطب المجتمع ISSN: 16845382 Year: 2012 Volume: 25 Issue: 4 Pages: 304-307
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract

Abstract:Background: Down's syndrome was the first of the chromosomal trisomy to be reported in 1959, Lejeune et al, with a prevalence of 0.7% live births. Garrod in 1894 who were noted a specific association between this syndrome and heart malformation. Aim: To find any relation between cytogenetic types of Down's syndrome and congenital heart disease, and early neonatal screening for congenital heart disease since early detection, help to prevent the future complication of pulmonary hypertension in old age.Patients and methods: A descriptive study done in AL-Yarmouk Teaching Hospital Neonatatology Department during one year period between January 1996- and 1997. The study involved 9000 live born infants screened for congenital anomaliese, we found 40 Down babies after full clinical examination to check the criteria of Down's syndrome and presence of congenital heart disease, then a blood sample was aspirated in a heparinized tubes and prepared for chromosomal analysis, those with congenital heart disease (CHD) were send for elective cardiograph, chest roentenography, Doppler echocardiography.Results: Out of the 40 Down's babies studied, 26(65%) were male and 14(35%) were female out of eight cases with CHD (20%) we found 3 (37.5%) had atrio-ventricular septal defect, 3(37.5%) had atrial septal defect,2(25%) had ventricular septal defect. Chromosomal pattern for all cases with CHD was Non disjunction (ND) triosomy 21.Conclusion: our study revealed no relationship between CHD types and chromosomal pattern. Prenatal screening for CHD in DS fetus and early neonatal screening for CHD as early detection, help to prevents the future complication of pulmonary hypertension in old age ,for whom new therapeutic option are available.Key words: cytogenetics, congenital heart disease.

الملخـص:تمت دراسة 9000 طفل حديث الولادة في مستشفى اليرموك التعليمي ,كمسح شامل لمعرفة حالات التشوهات الخلقية, وجد 40 طفل مصاب بمتلازمة داون بعد الفحص ألسريري لهم, وجد 8 منهم مصابين بتشوهات القلب، تم فحص الكر وموسومات لهم ,وجد كل الأطفال المصابين لديهم نفس النتيجة ,نستنتج لا توجد علاقة بين نوع فحص الكروموسومات وتشوهات القلب لدى الأطفال المنغوليين.لذا ينصح بأجراء فحص قبل الولادة للاجنه التي تحمل متلازمة داون للكشف عن تشوهات القلب أو فحص بعد الولادة مباشرة كلما يتم الكشف مبكر كلما نمنع مضاعفات ارتفاع ضغط الشريان الرئوي في الكبر حيث تتوفر وسائل علاجيه جديدة لذلك.


Article
Serum and Erythrocyte Magnesium Levels in Patients with Myocardial Infarction with or without Heart Failure

Authors: Laith S. Abdul-Al Haliim Al-Naqib --- Ahsan K. Abbas --- Basil N. Saeed*
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2013 Volume: 12 Issue: 3 Pages: 372-375
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

BACKGROUND :Magnesium (( Mg(1) )) is a mineral that is involved in over 300 reactions in the body. Magnesium is aPotent vasodilation ,and plays an important role in muscle contraction. It has been earlydocumented that Mg deficiency can precipitate ventricular arrhythmias and treatment with Mg hassome anti arrythmic effect. Moreover there is an ample evidence that a significant percentage ofpatients with IHD suffer from Mg. The risk of IHD increaseswith age, smoking, hypercholesterolaemia,diabetes mellitus, hypertension(1). Ischemic heartdisease presented as stable angina , unstableangina , myocardial infarction , ischemic heartfailure and ischemic cardiomyopathy. Thediagnosis of ischemic heart disease depend onclinical history and investigation including: *Ministry of Health AL-Bitar Hospital,Baghdad.Iraq.**Biochemistry Dept. Collage of Medicine University of Baghdad.*** Dept. Baghdad Medicine City. deficiency.OBJECTIVE : The objective of the present study is to measure Mg(2) levels in serum and RBCs of patients withsome forms of IHD. PATIENTS AND METHODS:The study was conducted in Baghdad hospital and Ibn – Al-Bitar Hospital.The 180 patients withIHD were divided into Two groups. Group I, 80 patients with Ischemic Heart Failure (IHF)(EF˂30) aged 65.75±5.97 year (50 males and 30 females), group II, 100 patients withMuocardial Infarction (MI)(EF˂50) aged 50.34±6.36 year (58 males and 42 females). Serum Mg and RBCs Mg weremeasured in all patient groups by Atomic Absorption Spectrophotometer.RESULTS: The(mean ±SD) value of serum and RBCs Mg in patients with both groups Ischemic Heart Disease(IHD) was significantly lower when compared with that of controls (p<0.05).The serum Mg levels (0.81±SD mmol/L) are significantly lower in the IHF group and in MI group (0.96±0.18 mmol/L)when compared with that of controls (1.00±0.17 mmol/L) (p˂ 0.001).CONCLUSION: The data obtained in present study revealed the decrease of Mg level in serum and RBCs in bothpatients groups, which affect the contractility of heart muscle and cardiac performance


Article
Pattern of congenital heart disease in newborn in Al-Diwaniyah maternity and children teaching hospital

Authors: Abbas Muhammed Hussain عباس محمد حسين --- Adel Jabbar Hussain عادل جبار حسين --- Qahtan Kayon Hmood قحطان خيون حمود
Journal: Al-Qadisiyah Medical Journal مجلة القادسية الطبية ISSN: 18170153 Year: 2013 Volume: 9 Issue: 15 Pages: 202-211
Publisher: Al-Qadisiyah University جامعة القادسية

Loading...
Loading...
Abstract

Background:CHD in the newborn is a problematic disease that need thorough investigation and may need urgent intervention.Objective:To review the pattern of CHD in newborns in Al-Diwaniyah city and to establish the relationship between CHD and certain parameters like sex,and consanguinity Patients and Methods: The study started at 1st of June 2008 till the 1st of January 2010 ,all newborn babies with suspected CHD were included in this study and undergo thorough history with specific attention on prenatal ,natal and postnatal history also questionnaire including sex ,full term or preterm delivery ,any previously affected sibling with CHD, the degree of consanguinity between the parents ,order of the patient in his family , then perfect general and cardiovascular system examination were performed to detect any other congenital or evidence of chromosomal abnormalities .Sixty seven neonates were enrolled in this study (7 of them were excluded because of prematurity)and 60 neonate were evaluated by chest X-ray, electrocardiograph, and echocardiography which done by expert pediatric cardiologist.Results :In this study we found that acyanotic CHD is more common than cyanotic type with VSD is accounting about 35% of cases followed by PDA 26.6% and then ASD 8.3% and TOF 8.3% ,also the study show that asymptomatic murmur is the commonest presentations of CHD in the newborn and consanguinity may be a risk factor.Conclusion: Early detection of CHD is very important for proper management so proper clinical examination and expert echocardiography is considered a gold standard for the diagnosis of CHD .Two dimensions echocardiography is also essential for the diagnosis special cardiac center should be established in our region (AL-Diwaniah)in order to manage the patient effectively without delay that may affect the out- come of the disease

تشكل امراض القلب الولاديه في حديثي الولاده مشكله مرضيه بحاجه الى فحوصات مستفيضه وربما تحتاج الى تداخلات علاجيه عاجله. من أجل مراجعة طبيعة امراض القلب الوراثيه في حديثي الولاده في مدينة الديوانيه ومن اجل توضيح العلاقه بين امراض القلب الولاديه وبعض المتعلقات مثل الجنس ودرجة القرابه. بدأت الدراسه في الاول من حزيران لعام2008 حتى الاول من كانون الثاني لعام 2010.تم شمول كل حديثي الولاده المشتبه لكونهم يعانون من امراض القلب الولاديه في هذه الدراسه وقد تم اخذ تاريخ المرض مع تاكيد على تاريخ ماقبل واثناء وبعد الولاده‘وكذالك تم السؤال عن الجنس وعن الطفل هل كان كاملا او مبتسرا اثناء الولاده،وهل يوجد طفل في العائله مصاب سابقا بامراض القلب الولاديه،وماهي درجة القرابه بين الاب والام ،وتسلسل الطفل في عائلته. وبعد ذالك اجري فحص سريري دقيق عام وخصوصا لجهاز الدوره الدمويه لتحديد وجود اي امراض ولاديه اخرى او علامات لخلل الكروموسومات. أدخل سبعه وستون وليد في هذه الدراسه,سبعه منهم استثنوا من الدراسه بسبب انهم كانوا مبتسرين ,وستون وليدا تم تقيمهم بواسطة اشعة الصدر وتخطيط القلب وفحص القلب بجهاز الايكو الذي اجري لهم من قبل طبيب متخصص بامرض القلب. وجد في هذه الدراسه بان امراض القلب الولاديه غير الازرقاقيه اكثر من امراض القلب الولاديه الازرقاقيه.وكانت الفتحه بين البطينين تشكل 35% من الحالات,وناسور القناة الشريانيه26,6%,والفتحه بين الاذنين8,3%,ورباعية فالوت8,3%.وكذالك اثبتت الدراسه ان النفحه غير المصاحبة بأي أعراض هي العرض الطبي الوحيد لاكثر امراض القلب الولاديه عند الولاده.وكذالك اثبتت الدراسه ان درجة القرابه القريبه تعتبر من عوامل الخطوره. التشخيص المبكر لامراض القلب الولاديه مهم جدا من اجل العلاج المثالي وان الفحص السريري وفحص الايكو الدقيق تعتبران اهم دعامات تشخيص امراض القلب الولاديه.ايكو القلب ذو البعدين كذالك مهم في التشخيص.وكذالك ضرورة انشاء مركز قلب تخصصي في مدينتنا من اجل المعالجه السريعه والدقيقه لامراض القلب الولاديه حتى تعطي نتائج علاجيه أفضل.


Article
Association between periodontitis and acquired coronary heart disease

Author: *Nadia Aftan AL Rawi M.Sc., Ph.D. **Athra M. Al. Waheb M.Sc.
Journal: Al-Kindy College Medical Journal مجلة كلية الطب الكندي ISSN: 18109543 Year: 2016 Volume: 12 Issue: 1 Pages: 10-15
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: The association between oral microbial infection and systemic disease is not a new concept. A major confounding issue is that oral infections often are only one of the many important factors that can influence systemic diseases .Objective: This study was conducted to evaluate the periodontal health status of patients with acquired coronary heart disease. Type of the study: Cross-sectional study.Methods: The study group consisted of 200 patients with an age range (35-70) years, having coronary heart disease .This study group were compared to a control group of non-coronary heart disease (200 individuals ) matching with age and gender. The oral parameters were examined including the periodontal conditions, assessment of periodontal loss of attachment as well as the missing teeth according to the World Health Organization criteria (1997)(1) were followed for diagnosis and recording of oral health status.Results: Results of the present study show that the total sample had a highly significantly periodontitis and periodontal loss of attachment with advancing age (P<0.01), while no statistically significant differences were found between males and females with periodontal condition and periodontal loss of attachment among the study group (P>0.05), while there was significant differences among their corresponding controls (P<0.05). High percentage of missing teeth was recorded among the study and control group. Highly statistically significant differences were seen between study and control groups in all the degree of severity related with periodontal conditions (P<0.001).Conclusion: The data showed that 50.5%, 35% of the control group were with periodontal disease and loss of attachment respectively compared with study group 68%, 58.5% . The present study indicate that periodontal disease more common among patients with CHD than among controls matched for age and gender. Thus the possibility that chronic oral infection or similar factor may he positively associated with CHD at least in form patients susceptible to CHD.Although causality cannot be inferred from the present data, the observed association between chronic oral infections and CHD for susceptible patients in the present study can not be excluded.


Article
The Relationship between Cytokines and Toxoplasma Infection in Heart Disease Patients

Authors: Haider S. Abdulhussein حيدر صباح عبد الحسين --- Bassad A. Al-Aboody بسعاد عقرب العبودي --- Ahmed H. Mohammed احمد حسن محمد
Journal: JOURNAL OF THI-QAR SCIENCE مجلة علوم ذي قار ISSN: 19918690 Year: 2017 Volume: 6 Issue: 2 Pages: 27-32
Publisher: Thi-Qar University جامعة ذي قار

Loading...
Loading...
Abstract

Toxoplasmosis is the general term for infection and disease in man and animal caused by a parasite called Toxoplasma gondii, this disease is prevalent among different categories of people, Heart disease are one of them. Because of the dormancy status of T. gondii, there is ambiguity and variation in the immunity of patients. This study aimed to investigate the immune status of heart disease patients infected with toxoplasmosis. Two hundred and fifty samples of both heart disease patients and controls had been tested by ELISA technique to detect anti-Toxoplasma Abs (IgG and IgM). The positive samples with toxoplasmosis were tested to detect the level of interleukins (IL-10, IL-12 and IL-17). The result of this study revealed the prevalence of toxoplasmosis among heart disease patient in about (43.33% IgG and 0.66% IgM). The results of interleukins appeared high level of IL-12 (82.85 pg./ml) in heart disease patients infected with toxoplasmosis when compared with control (60.97 pg./ml) with significant difference between them at p≤0.05, while there was no significant difference in IL-10 between patients and controls. The results also showed decreased level of IL-17 in patients with heart disease. The increased level of IL-12 in patient with heart disease infected with toxoplasmosis indicate to the activity of cell mediated immunity in those patients and may be lead to provoke an inflammatory status in the heart valves and muscle then worse heart disease to be sever and need complicated treatments.

داء المقوسات هو مصطلح عام للأصابة والمرض في الإنسان والحيوان يسببه طفيلي يعرف بالتوكسوبلازما، هذا المرض منتشر بين فئات مختلفة من البشر، ومن ضمنهم مرضى القلب . بسبب الحالة الساكنة (الكامنة) للطفيلي هنالك اختلاف وغموض في الحالة المناعية للمرضى المصابين بالطفيلي . هدفت هذه الدراسة إلى التحقيق في الحالة المناعية لمرضى القلب المصابين بداء المقوسات , وقد تم اختبار مائتين وخمسون عينه من كل من مرضى القلب والسيطرة(الأصحاء) بأستعمال تقنية اللأليزا (تقنية الانزيم المرتبط) للكشف عن الأجسام المضادة لطفيلي التوكسوبلازما , كذلك تم اختبار العينات الموجبة للتوكسوبلازما لتحديد مستويات الأنترلوكينات (10-IL, 12-IL ,17-IL) . أضهرت نتائج هذه الدراسة انتشارطفيلي التوكسوبلازما بين مرضى القلب بنسبة 43.33% للجسم المضاد ( IgG) و0.66 % بالنسبة للجسم المضاد( IgM) . أما نتائج اختبار الأنترلوكينات أضهرت أرتفاع مستوى الأنترلوكين 12- IL (lm ̸ pg 82.85 ) في مرضى القلب المصابين بطفيلي التوكسوبلازما عند مقارنتها مع عينات السيطرة الأنترلوكين 12 -IL ( ml ̸ pg 60.97 ) حيث اضهرت فرق معنوي بينهم عند0.05≥p , بينما لا توجد اختلافات واضحة في مستوى الأنترلوكين 10-IL بين مرضى القلب وعينات السيطرة , كذلك أضهرت النتائج أنخفاض في مستوى الأنترلوكين 17 في مرضى القلب. زيادة مستوى الأنترلوكين 12 في مرضى القلب المصابين بداء المقوسات يشير الى نشاط المناعة الخلوية في مرضى القلب ، ويمكن أن يؤدي إلى إثارة حالة التهاب في صمامات القلب والعضلات ثم أمرض القلب الأكثر شدة والحاجة للمعالجة المعقدة.


Article
Electro Cardiographic Features of PtientsWith Tetralogy of Fallot

Authors: Dhia’a Hassan --- Fadhil Al-Rubaiy --- Sadiq M. Al-Hamash
Journal: Al-Kindy College Medical Journal مجلة كلية الطب الكندي ISSN: 18109543 Year: 2007 Volume: 4 Issue: 1 Pages: 19-22
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: For many decades, the ECG was the workhorse of non-invasive cardiac test and today although other techniques provide more details about the structural anomalies in congenital heart diseases, ECG is likely to be part of clinical evaluation of patients with such diseases because it is inexpensive, easy to perform and in certain situations may be both sensitive and specific.
Objective: this study carried out to identify the pattern of ECG study in patients with TOF.
Methods: this is a retrospective study of 200 patients with TOF, referred to Ibn Al-Bitar cardiac center from April 1993 to May 1999. The diagnosis of TOF established by echocrdiographic, catheterization and angiographic study. For each patient, the ECG tracing had been analyzed for rhythm, p-wave, P-R interval, QRS axis, duration and T-wave in V1 and any chamber enlargement.
Results: The ECG analysis revealed that all patients had sinus rhythm, normal P-R interval and normal p-wave duration and amplitude, and normal QRS duration. All studied patients had one criteria of RVH and 95% of them had two or more of such criteria.
Conclusion: we found that in the absence of RVH criteria, the diagnosis of TOF is unlikely and the present of northwest axis should indicate canal type VSD.
Key words: ECG, TOF, congenital heart disease

Keywords

ECG --- TOF --- congenital heart disease


Article
Clinical and Angiographic Findings in Diabetic Versus Non-Diabetic Iraqi Patients with Ischemic Heart Disease (A Single Center Experience)

Author: Muataz Fawzi Hussein
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2011 Volume: 10 Issue: 3 Pages: 339-346
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

ABSTRACT:BACKGROUND:Diabetes mellitus (DM) is a common, chronic and complex metabolic disorder. Its direct and indirect effects on the vascular system are major causes of morbidity and mortality.OBJECTIVE:To verify the effects of diabetes mellitus on clinical presentation and angiographic findings in diabetic patients with ischemic heart disease as compared to non diabetic patients.PATIENTS AND METHODS:This cross-sectional descriptive study was conducted in the Iraqi Center of Heart Diseases during the period from November 2008 till June 2009. Two-hundred patients with ischemic heart disease (IHD) who were referred to the Iraqi Center for Heart Diseases were randomly included. Clinical history and examination were done; blood tests, electrocardiography and echocardiography were done for all patients. Patients were classified into 2 groups: 68 patients with diabetes mellitus and 132 patients without diabetes mellitus. Coronary angiography was done for all patients and the results were interpreted by two independent interventional cardiologists.RESULTS :There were 145 (72.5 %) males and 55 (27.5 %) females. The mean age of study population was 56.92 ± 3.9 years (56.57 ± 3.2 years for males, 57.91 ± 4.1 years for females).There were no statistically significant differences between diabetic and diabetic patients regarding sex, age, type of clinical presentation, presence of hypertension and family history of coronary heart disease. Diabetic patients were more likely to be smoker (61.7% vs. 48.4%, P = 0.01), to have dyslipidemia (53% vs. 35%, P = 0.03), left ventricular systolic dysfunction (61.7% vs. 48.4%, P = 0.045) left ventricular diastolic dysfunction (92.6% vs. 58.3%, P =0.03), more diseased coronary arteries (38.2% vs. 25.7%, P =0.009), more frequent left main stem involvement (13.2% vs. 3.8%, P =0.008) and more complex coronary lesions (60.2% vs 31.8%, P =0.00002).CONCLUSION:Diabetic mellitus has clear adverse effects on left ventricular systolic and diastolic functions and angiographic findings in patients with ischemic heart disease


Article
Prevalence and Risk Factors for Congenital Heart Anomalies Among Hospital Attendees in Mosul City

Author: Eman Ghanim Sheet Al-Hyali
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2015 Volume: 14 Issue: 2 Pages: 229-236
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

ABSTRACT:BACKGROUND : Congenital heart disease (CHD) define as abnormalities of heart structure that originate before birth, they are responsible for more deaths in the first year of life than any other birth defects.OBJECTIVE: To determine the prevalence of the identifiable CHDs and to identify risk factors that may predispose for its occurrence . METHODS: This is a case series hospital based study carried out in IB- IN- Al-Atheer teaching hospital of pediatric in Mosul city. during the period from April 2013 to April 2014 . 460 cases with CHD were compared with an equal number of controls selected from the general population and individually matched for age, sex, and family practitioner Information was obtained by Questionnaire sheets ,medical examination and investigations. RESULT: Out of 75320 attendants, 680 cases were referred to echocardiography unit where 460 cases of CHD were detected, the prevalence was (6.1/1000 patients). Atrial septal defect (42. %), ventricular septal defect was detected (30%) and Patent ductus arteriosus (9.3%) are the most common CHD detected. More than half of cases of CHD (86%) are detected at infancy with female- male ratio of 1.4:1 An association was found between family history, consanguinity and occurrence of CHD. Also an association was found between maternal risk factors such as mothers disease ,drug intake, obesity, smooking during pregnancy.CONCLUSION: CHD is a public health problem among infants and young children and there are many risk factors showed a significant effect on its occurrence such as positive family history, consanguinity and material risk factors during pregnancy So proper and timely counseling, regular antenatal care. folate supplementation especially during the most sensitive period of embryogenesis is essential to avoid congenital heart malformation


Article
Hypercholesterolemia as a risk factor for coronary heart disease

Loading...
Loading...
Abstract

Familial Hypercholesterolemia (FH) is a genetic disorder, an expression of a defect in the gene that is responsible for the production of LDL-C receptor. The current study was designed to determine the FH patients in the city of Sulaymaniyah for both sexes. The study included 213 samples, the number of males was 99 and the number of females was 114, both sexes ranged from (30-79) years.The results of cholesterol, triglyceride, high density lipoprotein (HDL-C), and low-density lipoprotein (LDL-C) in patients with hypercholesterolemia showed highly significant (P ˂ 0.01) for cholesterol and the concentration level in patients with hypercholesterolemia compared to the level of concentration of healthy.As concerns the effect of hypercholesterolemia on coronary heart disease, the results showed a significant increase (P ˂ 0.01) in cholesterol, triglycerides and LDL-C with a significant decrease in HDL-C concentration in people with heart disease compared with healthy people. triglyceride in patients with compared healthy people. (HDL-C and LDL-C) showed a significant decrease (P ˂ 0.01) in the concentration of HDL-C in patients with hypercholesterolemia compared to their level of concentration in healthy individuals, in relation to low-density lipoprotein (LDL-C) -C is the other (P ˂ 0.01) in.

فرط كولسترول الدم العائلي FH) Familial Hypercholesterolemia) هو إضطراب وراثي وهو تعبير عن خلل في الجين المسؤول عن إنتاج مستقبلReceptor البروتين الدهني منخفض الكثافة ( Low – Density – Lipoprotein (LDL-C . صممت الدراسة الحالية لمرضى فرط كولسترول الدم العائلي (FH) في مدينة السليمانية لكلا الجنسين ، وشملت الدراسة (213) عينة وكان عدد الذكور (99) وعدد الأناث (114) وتراوحت أعمار كلا الجنسين من (30-79) سنة .أشارت نتائج قياس تركيز كل من ( الكولسترول ، الدهون الثلاثية ، البروتينات الدهنية عالية الكثافة HDL-C والبروتينات الدهنية واطئة الكثافة LDL-C ) لدى المرضى المصابين بفرط كولسترول الدم ارتفاعاﹰ عالي المعنوية ملحوظاﹰ (0.01 ˂ P) ﹰللكولسترول والدهون الثلاثية لدى المرضى مقارنةﹰ بالأصحاء ، في حين أظهرت نتائج البروتينات الدهنية ( HDL-C و LDL-C) إنخفاضاﹰ معنوياﹰ كبيراﹰ (0.01 ˂ P) في مستوى تركيز البروتينات الدهنية العالية الكثافة HDL-C لدى مرضى فرط كولسترول الدم مقارنةﹰ بمستوى تركيزه لدى الأصحاء ، أمـﱢــا بالنسبة للبروتين الدهني المنخفض الكثافة LDL-C فهو الأخر عالي المعنويةﹰ (0.01 ˂ P) في مستوى تركيزه لدى مرضى فرط كولسترول الدم مقارنة بمستوى تركيزه للاصحاء . أمــﱢـا عن تأثير العامل المرضي على المصابين بفرط كولسترول الدم وهو مرض القلب التاجي coronary heart disease ، فقد أظهرت النتائج وجود زيادة معنوية (P ˂ 0.01) في الكولسترول والكليسيريدات الثلاثية TG و LDL-C مع أنخفاض ملحوظ لتراكيز HDL-C لدى الأشخاص المصابين بأمراض القلب مقارنةﹰ بالأصحاء .

Listing 1 - 10 of 74 << page
of 8
>>
Sort by
Narrow your search

Resource type

article (74)


Language

English (59)

Arabic and English (4)

Arabic (2)


Year
From To Submit

2018 (7)

2017 (8)

2016 (5)

2015 (7)

2014 (3)

More...