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Article
Prevalence of anti-hepatitis C virus antibodies among blood donors and risky groups in Diyala

Author: Abdul-Razak S. Hassan
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2008 Volume: 50 Issue: 4 Pages: 467-470
Publisher: Baghdad University جامعة بغداد

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Abstract

Objective: To determine the prevalence of hepatitis C virus (HCV) infection among blood donors and risky population in Diyala province.
Materials and methods: In this retrospective study, the records of HCV screening and confirmatory tests were reviewed for the period 1996-2001.Third generation Enzyme-linked immunosorbant assay (ELISA) and Enzyme immunoblot assay were used as screening and confirmatory tests respectively.
Results: The prevalence of HCV infection among blood donors was 0.15%, with the highest in 1997. The highest prevalence rates were found among multiple blood recipient; hemophilia, thalassemia and hemodialysis patients (27.3%, 16.9% & 14.3%) respectively. Whereas, the patients with chronic hepatitis B infection and those with acute icteric hepatitis showed slightly elevated prevalence (2.9% & 2.1%) respectively. The overall prevalence in the province was 9.9/105 population. The mean age of infected patients was 29.7 years and the male: female ratio was 3:1.
Conclusion: The prevalence of HCV infection in Diyala population is relatively low. However, the HCV infection is concentrated in certain risky groups, particularly multiple blood recipients.


Article
SEROCONVERSION RATE OF HEPATITIS C VIRUS INFECTION AMONG HAEMODIALYSIS PATIENTS IN AL-KADHIMIYA TEACHING HOSPITAL (DIALYSIS UNIT)

Authors: Arif S Malik عارف سامي مالك --- Hasanain MH AL-Rubaie حسنين الربيعي
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2011 Volume: 9 Issue: 4 Pages: 343-349
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

BackgroundHepatitis C virus (HCV) infection is a serious public health problem throughout the world. Chronic haemodialysis patients are at higher risk for acquiring hepatitis C virus (HCV) infection.ObjectiveTo assess the rate of seroconversion of hepatitis C virus (HCV) infection every month for one year duration, to evaluate the possible associated risk factors and the relationship of hepatitis C virus infection with blood transfusion and duration of hemodialysis.MethodsFifty seven patients, 37 males (65%) and 20 females (35%), who were on regular haemodialysis in Al-Kadhimiya Teaching Hospital was studied during the period between January 2009 and December 2009. Patients were analyzed monthly with anti –HCV antibodies using a commercial enzyme-linked immuno-sorbant assay BioKit (bioelisa HCV 4.0) and serum Alanin aminotransferase measurements.ResultsTwenty three patients (40.3%) were HCV positive of whom, 13 were males (56.5%) and 10 were females (43.5%). History of blood transfusion, number of blood transfusion and duration of haemodialysis, had significant correlation in acquiring HCV infection.ConclusionSeroconversion of HCV infection was of high rate incidence (40.3%). Duration of HD, history of blood transfusion and number of blood transfusion(s) are factors affect the rate of seroconversion of HCV infection in patients on regular HD. The higher rate of seroconversion of HCV infection needs further research to identify the causes and to establish a well organized prophylactic program by using more sophisticated and accurate investigation.Key wordsHepatitis C virus infection, Hemodialysis, Chronic renal failure


Article
Hepatitis C virus infection and abortion among pregnant women in Mosul city
عدوى فيروس التهاب الكبد C والإجهاض بين النساء الحوامل في مدينة الموصل

Authors: Sumaya T. Saihood --- Nadya I. Salih --- Israa H. Saadoon
Journal: The Medical Journal of Tikrit مجلة تكريت الطبية ISSN: 16831813 Year: 2008 Volume: 1 Issue: 141 Pages: 161-164
Publisher: Tikrit University جامعة تكريت

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Abstract

Infection with HCV is a major public health problem and is of particular concern duringpregnancy. Identification of transmission risk factors is essential for the development ofappropriate interventions. The aim of this study was to evaluate infection with HCV in pregnantwomen and to identify the correlation between HCV infection and abortion. The current studyincluded 875 pregnant women attended to three hospitals in Mosul City (Al-Batool, Al-Khansaa,and General Mosul Hospital) during the period from the beginning of July 2007 to the end ofSeptember 2007. The study revealed that infection with hepatitis C virus (HCV) was found in 45out of 875 pregnant women (5.14 %). There was significant correlation between HCV infectionand abortion. The risk of HCV infection increased with increasing number of abortions.

عدوى فيروس (سي) هو مشكلة صحية عامة رئيسية ومصدر قلق خاص خلال الحمل. تحديد عوامل الخطر انتقال أمر أساسي من أجل تطوير التدخلات المناسبة. وكان الهدف من هذه الدراسة لتقييم الإصابة بفيروس الكبد الوبائي في الحوامل نساء والتعرف على العلاقة بين فيروس التهاب الكبد الوبائي، والإجهاض. الدراسة الحالية وحضر وشملت 875 امرأة حامل الى ثلاثة مستشفيات في مدينة الموصل (سورة بتول، الخنساء، والجنرال مستشفى الموصل) خلال الفترة من بداية يوليو 2007 الى نهاية عام سبتمبر 2007. وكشفت الدراسة التي تم العثور عليها مع عدوى فيروس التهاب الكبد الوبائي (سي) في 45 من أصل 875 امرأة حامل (5.14٪). كان هناك ارتباط كبير بين فيروس التهاب الكبد الوبائي والإجهاض. تزيد من خطر الإصابة بعدوى هذا الفيروس مع تزايد عدد حالات الإجهاض.

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