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Article
The Effect of Aspirin on Histology of Placenta

Author: Eman Ghanim Sheet Al-Hylli
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2014 Volume: 13 Issue: 3 Pages: 434-441
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT: BACKGROUND :Preeclampsia (PE )is a potentially life-threatening hypertensive disorder affecting_ 2-7% of all pregnancies , It is a leading cause of maternal mortality ,and associated with high perinatal mortality and morbidity, including intrauterine growth restriction (IUGR) and prematurity. A daily low dose of aspirin (60-80 mg /day) may use for prevention and treatment of PE and fetal growth retardation in pregnant women at risk. OBJECTIVE: To assess the influence of aspirin therapy on the histology of placenta from mothers with PE and to correlate the findings with those from pre -eclamptic mothers but not using aspirin during their pregnancy and with placenta from normal Pregnancies .METHODS: This study was carried out on one hundred twenty –pregnant women, thirty five with uncomplicated pregnancy and eighty five mothers with PE , fifty of these hypertensive women on aspirin therapy since first trimester. RESULT: It was found that mothers with pre- eclampsia either take aspirin or not had relatively smaller, irregular placentae. Histological features of vascular insufficiency like thrombosis, cytotrophoblastic cellular proliferation, fibrin plaque formation etc. were present in more or less similar amount in both groups of hypertensive placentae. Babies of such mothers were mostlysmall for date. CONCLUSION :Despite the little improvement in outcomes of the aspirin treated pregnancy, , histologic evidence of placental pathology persisted in the majority of women with PE. so aspirin therapy is not effective in preventing and treatment PE


Article
Noncompliance With Antihypertensive Drugs Among Patients with Essential Hypertension in Sulaimani City

Authors: Omed H.K Hawrami --- Manar Hisham Abdulla
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2016 Volume: 15 Issue: 2 Pages: 140-147
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND: Hypertension is a common chronic disease in Iraq, noncompliance with medications is one of the most important reasons for uncontrolled hypertension.OBJECTIVE: This study was designed to detect the percentage and the causes of noncompliance with antihypertensive drugs among the study sample.PATIENTS AND METHODS: A cross-sectional study was conducted during the period from August 1st 2012 to February 28th 2013, at four primary health care centers in Sulaimani city, 309 patients were included in the study. Non compliance was tested by using self reported Morisky- Green adherence scale.RESULTS: 54.7% of the patients were non compliant with the antihypertensive drugs, ( 55%males and 45% females), Statistically significant factors were: young age( 62.5%), female gender (63.3%), low educational level (80.5%), being unemployed (71.7%), duration of hypertension > 10 years( 65.2%), and when the source of medication was from health care centers (75.6%).CONCLUSION: A significant percentage of the patients were non compliant with their anti-hypertensive drugs, the main causes of non compliance were patient, physician, and drugs related, respectively.

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