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Authors: Issam T. Abdul-Wahaab --- Malak A. Al-Yawer --- Fadhel A. Al – Khafaji
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2015 Issue: 2 Pages: 309-312
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND: Coriandrum Sativum is a native of Mediterranean region and is grown in North Africa, central Europe, and Asia as culinary herb and medicament. In addition to the other health-supporting reputation, coriander has hypoglycemic, hypolipidemic, and aphrodisiac effects.OBJECTIVE:To study the effect of Coriandrum Sativum on process of spermatogenesis.MATERIALS AND METHODS: Coriandrum sativum was given daily to mature male rats in a dose of 50mg/ 100g body weight for 14 days. 10% formalin fixed paraffin-embedded tissue sections were performed for histological and morphometrical studies.RESULTS: Histological study showed wider seminiferous tubules & increased spermatocytes population with an increased sperm density in the lumen of the tubules. Morphometrically, the diameters & thickness of the germinal epithelia of the seminiferous tubules were significantly increased in coriander treated rats than that of the control group.CONCLUSION: Coriandrum sativum appeared to be stimulant to the process of spermatogenesis.


Article
Immunohistochemical Study of Leydig Cells in the Testicular Interstitial Tissue of Rats Treated with Tribulus Terrestris Using P450scc.

Authors: Issam T. Abdul-Wahaab --- *,Malak A. Al-Yawer --- *,Fadhil A. Al – Khafaji*
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2015 Volume: 14 Issue: 1 Pages: 140-144
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND: Tribulus terrestris has been commonly used in folk medicine to energize, vitalize and improve sexual function and physical performance in men and laboratory rats.OBJECTIVE: To study the effect of Tribulus terrestris on the number of Leydig cells.MATERIALS AND METHODS: Tribulus terrestris was given to mature male rats as an oral single herbal suspension in a dose of 2.0mg /1000gbody weight for 14 days to stimulate spermatogenesis. Formalin fixed paraffin-embedded tissue sections were performed for histological, immunohistochemical and morphometrical studies.RESULTS: Histological study revealed wider seminiferous tubules and increased spermatocytes population with an increased sperm density inside the lumen of the tubules. Morphometrically, the diameters of seminiferous tubules and thickness of the germinal epithelia were significantly increased in Tribulus terrestris treated rats than that of the control group. There was no significant difference between the number of Leydig cells in the control and experimental groups.CONCLUSION: The activity of Leydig cells, manifested by the increments in the diameters, thickness of germinal epithelia and the density of the sperms inside seminiferous tubules, was increased but their number remain unaffected in spite of using the aphrodisiac agent, Tribulus terrestris.

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