research centers


Search results: Found 69

Listing 1 - 10 of 69 << page
of 7
>>
Sort by

Article
A STUDY OF LEPTIN & LIPID PROFILE IN A SAMPLE OF IRAQIPATIENTS WITH KNEE OSTEOARTHRITIS.

Authors: Zina H. Abdul-Qahar --- Mohammed H. Alosami --- Kismat M. Turki
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: PISSN: 00419419 / EISSN: 24108057 Year: 2008 Volume: 50 Issue: 3 Pages: 372-376
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: New data suggests that joint damage in Knee Osteoarthritis (KOA) may be
caused by systemic factors like adipose tissue products; Adipokines, which may provide a
metabolic link between obesity & KOA. Recently, one of the known adipokines named
LEPTIN has been linked to KOA because it can be detected in serum & synovial fluid of
patients with KOA.
Objective: To evaluate the contribution of Leptin & serum lipids to the pathophysiology of
Osteoarthritis in Iraqi patients with Knee OA.
Subjects& Methods: The study was carried on 90 subjects divided into four groups:
Knee Osteoarthritis cases group (n=60).
Control group (n=30).
Obese subjects group (n=60).
Non-obese subjects group (n=30).
KOA cases were diagnosed clinically whereas obesity was specified by BMI ≥25kg/m2. For
all subjects studied measurements of fasting serum leptin and lipid profile have been done.
Results: Mean serum leptin level was significantly higher in KOA cases compared to control
group (P<0.001), and higher in obese than non-obese subjects (P<0.001). Serum leptin level
also showed a strong positive correlation with BMI (r=0.501, P<0.01).
Conclusions: Leptin may play an important role in the pathogenesis of KOA. In addition
abnormal lipid profile and obesity are important risk factors for KOA.


Article
Significance of crystals in patients with osteoarthritis of the knee joint

Authors: Mohammed-Taher Rasool محمد طاهر رسول --- Saad M Al-Hasani سعد الحسني
Journal: Annals of the College of Medicine Mosul مجلة طب الموصل ISSN: 00271446 23096217 Year: 2005 Volume: 31 Issue: 2 Pages: 66-69
Publisher: Mosul University جامعة الموصل

Loading...
Loading...
Abstract

To identify the relation between the presence of calcium pyrophosphate dihydrate crystals (CPPD) and clinical, laboratory, and radiographic findings in patients with osteoarthritis of the knee joint, an analytical study was done in 2001, which included 100 patients with osteoarthritis of the knee joint. Synovial fluid analysis with the examination of a wet preparation under polarized microscopy was conducted for each patient. The study included a comparison between CPPD positive patients and those who are negative for these crystals. CPPD crystals were identified in 48% of the patients. The study shows a significant association of CPPD crystals with genu-valgum deformity, limited flexion and extension, elevated erythrocyte sedimentation rate (ESR) and cloudy inflammatory synovial fluid with poor viscosity. We concluded that CPPD deposition is associated with more disabling and deforming arthritis of the knee joint. Clinical criteria are needed to identify patients with occult CPPD deposition disease.


Article
Osteoarthritic Deformities in the Knee Joint
تشوهات ضمورية لمفصل الركبة (سوفان الركبة)

Author: Raof R. Merza د. رؤوف رحيم ميرزا
Journal: IRAQI JOURNALOF COMMUNITY MEDICINE المجلة العراقية لطب المجتمع ISSN: 16845382 Year: 2008 Volume: 21 Issue: 1 Pages: 69-74
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract

Abstract:Objective: To determine the correlation between knee joint deformities and duration of osteoarthritis (OA).Methods: A prospective randomized study was enrolled 100 patients, in Sulaimany City, in Iraqi-Kurdistan region, with radiographic finding of unilateral or bilateral OA of the knee joints; age, gender, obesity, family history, and duration of the OA were taken in consideration. Secondary OA were excluded from this study. Results: out of 100 patients, 21 had deformity (21%), of which 17 patients (17%) had varus, 2 patients (2%) had valgus, and other 2 patients (2%) had fixed flexion deformity.OA durations were ranging from 1 to 15 years; therefore we categorized the patients according to the durations of OA into 3 groups (1-5, 6-10, and 11-15). From 1 to 5 years there were 72 patients, of these 9 patients had deformity (12.5%), 63 patients with out deformity. From 6 to 10 years there were 17 patients, of these 5 patients had deformity (29.41%), 12 patients with out deformity. From 11 to 15 years ther were 11 patients, of these 7 patients had deformity (63.64%), 4 patients with out deformity. Conclusion: There is significant positive correlation between deformities and duration of the knee OA. Key words: Osteoarthritis, knee, and deformities.

الملخص:الهدف: أيجاد العلاقة بين تشوهات المفصل الركبة ومدة الأصابة بألألتهاب الضمورية (سوفان الركبة).الوسائل: تمت دراسة عشوائية مأمولة ل (100)من المرضى المصابين بسوفان مفصل الركبة, والذين أخذ لهم الأشعة السينية ) ( x-ray لغرض التشخيص, أخذاً بالاعتبار العمر, الجنس, السمنة, تأريخ المرض العائلي, ومدة الأصابة بالمرض.و قد عزلت حالات السوفان الثانوية من هذه الدراسة.النتائج: لقد أظهرت النتائج بأن 21 مريضاً(21%) من أصل 100 مرضى كانوا مصابين بتشوهات مفصل الركبة, وأن 17 مريضا (17%) كانوا مصابين بتشوه الفحجاء أو الساق المقوسة ( varus ) ومريضتان (2%) كانتا مصابتين بعاهة الساق الروحاء أو المنحرفة الى الخارج ( valgus) ومريضين اّخرين (2%) كانا مصابين بعاهة الأنثناء الثابت ( .( Fixed flexion deformity وقد امتدت مدة الاصابة بسوفان الركبة بين المرضى من 1 الى 15 سنة, ووفق ذلك قد تم تقسيم المرضى الى ثلاث مجاميع (1-5, 6-10 , 11-15) سنوات , وجدت هناك 72 مرضى من 1-5 سنوات, كانت تحتوى على 9 حالات التشوه (12.5%), و63 حالة بلا تشوه .ومن 6-10 سنوات كان هناك 17 مرضى ً منهم 5 حالات التشوه(29.41%), 12 حالة بلا تشوه .وكذلك من 11-15 سنوات كان هناك 11 مرضى ومنهم 7 مصابين بالتشوه (63.64%) و4 مرضى كانوا بلا تشوه.الأستنتاج: قدثبت بأن هناك علاقة ايجابية هامة بين التشوهات ومدة الأصابة بسوفان الركبة.


Article
Risk factors in an association with the osteoarthritis of the knee in Mosul city
عوامل الخطورة المرتبطة مع سوفان الركبة في مدينة الموصل

Author: Yakdhan Z. Alsaleem يقظان زهير السليم
Journal: Annals of the College of Medicine Mosul مجلة طب الموصل ISSN: 00271446 23096217 Year: 2013 Volume: 39 Issue: 1 Pages: 84-88
Publisher: Mosul University جامعة الموصل

Loading...
Loading...
Abstract

ABSTRACTBackground: Osteoarthritis of knee is a common cause of pain and disability. It is becoming increasingly prevalent worldwide due to its association with an aging and obesity. Objective: The aim of this study was to examine the associations between body mass index, gender, Islamic praying, praying in sitting position, usage of stairs, history of traumas, diabetes, hypertension, and hypothyroidism as risk factors for knee osteoarthritis in population of Mosul city.Patients and methods: This study is a case - control design, it was conducted through the period from Jan 2010 - Jan 2011 in the orthopedic outpatient clinic of Aljumhoori Teaching Hospital in Mosul. The target population of this study consisted of 213, 71 cases (61 females, 10 males), their ages mean 51.77 years, and 142 as controls. Results: The body mass index was higher in cases and shows highly significant difference between cases and control (p ≤ 0.000). Sex distribution in knee osteoarthritis revealed that there was significant difference between females and males as cases of osteoarthritis, (P ≤ 0.0001). Normal Islamic praying, Praying in sitting position, usage of stairs, appeared to be an associated risk factors, history of trauma was significantly higher in cases, while diabetes, hypertension, and hypothyroidism was not associated with the development of osteoarthritis of the knee.Conclusion: Females as a gender, obesity, Islamic praying in sitting position and history of trauma to the knee are important risk factors of osteoarthritis of the knee, while diabetes, hypertension and hypothyroidism are not associated with knee osteoarthritis.Keywords: Osteoarthritis, knee, risk factors.

الخلاصةالخلفية: سوفان مفصل الركبة هو مسبب أساسي وشائع للألم وتدني الكفاءة والقدرة على العمل وهو شائع في كل أرجاء العالم لإرتباطه مع تقدم أعمار الناس ولتنامي ظاهرة السمنة.الأهداف: هدف الدراسة هو معرفة الترابط بين الجنس, السمنة, الصلاة الإسلامية المعتادة وفي وضع الجلوس والإصابات السابقة لمفصل الركبة وداء السكر وارتفاع ضغط الدم الشرياني وقصور الغدة الدرقية كعوامل خطورة عند المرضى المصبين بسوفان الركبة في مجتمع مدينة الموصل.المرضى وطرق العمل: الدراسة هي حالات مع عينة ضابطة وقد أجريت خلال الفترة بين الأول من كانون الثاني لسنة 2010 والأول من كانون الثاني لسنة 2011 في العيادة الخارجية للمستشفى الجمهوري في الموصل. عدد المشاركين في الدراسة هو 213 منهم 71 حالة و142 شخص كعينة ضابطة أعمارهم تتباين بين (25 – 70 سنة) بمعدل 51,7 سنة . النتائج: مؤشر كتلة الجسم كان أعلى في الحالات وأظهر فرق معنوي ذو أهمية إحصائية عالية بين الحالات والعينة الضابطة, وهناك أيضا اختلاف بين الجنسين في سوفان الركبة أظهر بأن فرق معنوي كبير بين الإناث والذكور كحالات سوفان المفاصل. الصلاة الإسلامية المعتادة, الصلاة في وضع الجلوس واستخدام السلالم تعتبر عوامل خطورة غير مباشرة مرتبطة بسوفان الركبة. الإصابات السابقة أظهرت فرقا معنويا لدى الحالات. بينما كان داء السكر وإرتفاع ضغط الدم الشرياني وقصور الغدة الدرقية لايرتبطون بتقدم سوفان الركبة. الاستنتاج : الإناث بصورة عامة, السمنة, الصلاة الإسلامية في وضع الجلوس والإصابات السابقة لمفصل الركبة تعتبر عوامل خطورة مهمة لمرض سوفان مفصل الركبة. بينما داء السكر, إرتفاع ضغط الدم الشرياني وقصور الغدة الدرقية لاترتبط بمرض سوفان مفصل الركبة.

Keywords

Osteoarthritis --- knee --- risk factors


Article
Arthroscopic debridement and lavage of knee joint osteoarthrosis

Author: Zuhair Gheni Abd Ali
Journal: Muthanna Medical Journal مجلة المثنى الطبية ISSN: 2226146x Year: 2016 Volume: 3 Issue: 1 Pages: 34-37
Publisher: Al-Muthanna University جامعة المثنى

Loading...
Loading...
Abstract

Recent advances in instrumentation and the growing understanding of the pathophysiology of osteoarthrosis of the knee joint have led to increase the use of arthroscopy for the management of degenerative arthritis of the knee, during this study 50-patient perform to them arthroscopic debridement and lavage from October 2010- April 2014, 30 male patients and 20 female patientin multicenter in Baghdad and Al Najaf cities, patient age range from 40-60 year, all with single knee joinst eoarthrosis, our procedure include debridement and lavage of the hypertrophied synovium and osteophyte and subchondral penetration, in most patient short term symptomatic relieve can be achieved with the arthroscopic debridement and lavage of the osteoarthritic knee joint, the greater symptomatic relieve and more persistent pain relieve can be achieved in patient who have acutonsent of pain, mechanical disturbance from cartilage or meniscal fragment, normal knee joint axis, and minimal radiographic evidence of degenerative osteoarthrosis.


Article
Age Influence on Knee Joint Flexors

Author: Dr Sameer Abdul Wahid , Dr. Med. Rehabilitation. , M.Sc.
Journal: Al-Kindy College Medical Journal مجلة كلية الطب الكندي ISSN: 18109543 Year: 2012 Volume: 8 Issue: 2 Pages: 6-11
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background : Knee flexors tightness has been documented in apparently healthy adults and in those with musculoskeletal problems, but the influence of age on the tightness has not been studied in Iraq. This study was therefore designed to determine the influence of age on knee flexors tightness in apparently healthy subjects.Methods: Knee flexors tightness was measured using the active knee extension test (AKET) in 200 apparently healthy male and female subjects, aged 13 to 59 years. The subjects were recruited into 5 age groups using the purposive sampling technique.Knee flexors tightness was compared across the age groups using one-way analysis ofvariance (ANOVA). The independent t-test was used to compare knee flexors tightness on both lower limbs in male and female subjects.Results: Subjects' mean age was 29.63 ± 16.72 years. All subjects had knee flexors tightness (absolute extension lag) and this increased with age up to age group 40-49 years. The male subjects had significantly higher knee flexors tightness than the females in all the age groups.Conclusion: This study suggests that knee flexors tightness increases in apparently healthy persons from adolescent up to age 40-49 years and it is higher in males than females.Key words: knee flexors tightness, age, active knee extension test


Article
External fixation of compound femoral shaft fractures in knee flexion position

Authors: Mohamed Jaffer Jawad --- Raed A. Saadoon
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2015 Volume: 14 Issue: 1 Pages: 35-39
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract

Background: Compound femoral shaft fracture (open fracture) are unsuitable to be treated by internal fixation primarily, in these situation external fixation is the treatment of choice.Aim of the study: The aim of this method (fixation of compound femoral shaft fractures using external fixators in knee flexion position) is to have a good range of knee movements immediately, post operation and later on, in comparism to classical method (external fixation in knee extension). Methods: The role of external fixation in the management of compound femoral shaft fractures is reviewed based on a study of 40 patients with compound femoral shaft fractures managed by an A O external fixator in extended knee position ( 20 patients during the period from 2003 – 2005 ) and knee flexion position ( 20 patients during the period from 2006 – 2009 ).Results: Results showed that those patients with fixation in knee flexion position have much better range of knee joint movements compared with those with knee extension position at time of fixation , without any significant differences in the of fracture healing between the 2 groups.Conclusion: External fixation of femoral fractures in knee flexion position give good range of knee motion in early and late follow up over fixation in knee extension.


Article
Patient Satisfaction after Total Knee Replacement Regarding pain and function
قناعة المريض بعد عملية زرع الركبة الكامل اعتمادا على الالم والوظيفة عملية تبديل مفصل الركبة الكامل هي احد الخيارات المهمة لتقليل الالم و تحسين وظيفة المفصل في المرضى المصابين بالفصال العظمي الشديد في الركبة.

Authors: AbdulJabbar Rasheed Abed عبد الجبار رشيد --- Mohammed Jumaah Karem محمد جمعه --- Ahmed Ayad Malallah --- احمد اياد
Journal: IRAQI JOURNALOF COMMUNITY MEDICINE المجلة العراقية لطب المجتمع ISSN: 16845382 Year: 2017 Volume: 30 Issue: 4 Pages: 182-189
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract

Abstract: Background: Total Knee Replacement is one of the most successful and effective surgical option to reduce pain and restore function for patients with severe osteoarthritis of the knee.Objectives: To evaluate the result of Total Knee Replacement regarding patient’s satisfaction in treating osteoarthritis of the knee.Patients and methods: A prospective cohort study was conducted at AL-Yarmouk teaching hospital from December 2014 to June 2016 in which forty-four patients with late stage knee OA who underwent TKR were included in the study. Outcomes was assessed according to OKS questionnaire. Participant demographics and baseline characteristics and presence of comorbidities were recorded. Then the results were recorded accordingly.Results: Among forty-four Total Knee Replacement performed, 84.09% resulted in patient satisfaction at three months post operatively, which increased to 93.1% at six months after surgery.Conclusion: Total Knee Replacement is useful technique for reducing pain and restoring good function for the joint.

الهدف:- تقييم نتائج عملية تبديل مفصل الركبه بالاعتماد علا قناعة المريض في علاج ا بالفصال العظمي الشديد في مفصل الركبه.طريقه العمل:- دراسة استطلاعية خلال فترة ثمانية عشر شهرا ، تم خلالها تشخيص اربع واربعون حالة فصال عظمي شديد في مفصل الركبة ثم خضعت لعملية تبديل المفصل في مستشفى اليرموك التعليمي. هؤلاء المرضى خضعوا لاختبار تقييمي عن طريق استبيان يقدم اليهم في الشهر الثالث والسادس بعد اجراء العملية لتقييم قناعتهم بالاعتماد على اسئله تخص الالم وتقييم وظيفة المفصل.النتائج:- من اربع واربعين حالة فصال عظمي شديد مفصل الركبه ، وجدنا ان نسبه قناعة المرضى تقدر بحوالي 84.09% بعد ثلاثه اشهر من العملية وقد ازدادت لتصل الى 93.18% بعد سته اشهر.الاستنتاج:- عملية تبديل مفصل الركبه هي عملية مفيدة لتقليل الالم واعادة الوظيفه للمفصل.


Article
Evaluation of The Cinical Use of Silymarin in Knee Osteoarthritis: Application of the Dual Inhibitory Concept of Cyclooxygenase and 5-Lipoxygenase

Author: Intesar Tariq Numan
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2007 Volume: 6 Issue: 4 Pages: 333-340
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

ABSTRACT:BACKGROUND:Many compounds from natural sources, including silymarin, proved to have effective inhibitory effects on cyclooxygenase (COX) and 5-lipoxygenase (5-LO) in vitro qnd experimental animals. The exellent pharmacological pre-clinical profile of these compounds indicates a broad range anti-inflammatory effectiveness devoid of the most troublesome side effects, which have at least impart impaired the clinical use of the classical COX inhibitors, including the newer selective COX-2 inhibitors.OBJECTIVES:This project designed to evaluate the clinical utility of silymarin, as a dual inhibitor of COX and 5-LO, as a single agent or in combination with non-steroidal anti-inflammatory drugs (NSAIDs) of both types, selective and non-selective COX inhibitors, in the treatment of knee osteoarthritis (OA).PATIENTS AND METHODS:Randomized, double blinded clinical study was performed on 220 patients who have symptomatic and radiologic evidence of painful OA of the knee. Patients were allocated into five groups, treated with either meloxicam (15mg/day), piroxicam; (20mg/day), silymarin (300mg/day) + piroxicam (20mg/day), silymarin (300mg/day) + meloxicam (15mg/day) or silymarin (300mg/day) alone. The treatment was followed for 8 weeks through measurement of the clinical effects of drugs each 7 days, using the Knee Injury and Osteoarthritis Outcome Score (KOOS) system.RESULTS:The results showed that silymarin, when used alone or in combination with NSAIDs resulted in significant improvement in the components of KOOS, higher than that produced by meloxicam or piroxicam when each used alone.CONCLUSION:In conclusion, oral administration of 300mg/day silymarin in OA patients produced very well characterized analgesic and anti-inflammatory activities, and when co-administered with piroxicam or miloxicam improves their therapeutic profile.

Keywords

Silymarin --- Osteoarthritis --- Knee injury --- KOOS.


Article
Bilateral genu varus (bowlegs) at early childhood in Mosul

Authors: Mahmood A. Aljumaily محمود عبد الجميلي --- Yakdan Z. Alsaleem يقظان زهير السليم
Journal: Annals of the College of Medicine Mosul مجلة طب الموصل ISSN: 00271446 23096217 Year: 2012 Volume: 38 Issue: 2 Pages: 87-90
Publisher: Mosul University جامعة الموصل

Loading...
Loading...
Abstract

ABSTRACTBackground: Genu varus deformity (bowlegs) is deviation of leg distal to knee toward midline, it is very common in early childhood. No data is available in apparently healthy Iraqi children.Objective: To identify the common causes of genu varus, and to evaluate its correction.Patients and methods: it is case series study; two hundred and thirteen children with bilateral genu varus deformities were included from Orthopedic Outpatient Clinic, Aljumhoori Teaching Hospital. The intercondylar distance was measured every 6 months during the period of follow-up which ranged between 2- 6 years. Results: Physiological genu varus was the commonest cause, 153 children (71.8%), their mean intercondylar distance was 3.42 ± 0.93, corrected spontaneously within two years. Nutritional rickets was the second cause in 58 patients (27.2%), their mean intercondylar distance was 4.22 ± 0.92 corrected spontaneously with medical treatment within 4 years. Two patients had vitamin D resistant rickets (hypophosphataemia), their deformities increased with growth. Conclusion: The most common cause of bilateral genu varus was physiological, usually corrected spontaneously within two years. Nutritional rickets was the second cause which leads to more severe genu varus, and delay its correction.

الخلاصةالخلفية: يعد الانحراف الإنسي للركبتين في الطفولة المبكرة من الحالات الشائعة جدا. ولا تتوفر لنا معلومات حول هذه الحالة عند الأصحاء ظاهريا من الأطفال العراقيين.الأهـداف: لتقديم نمط الانحراف الإنسي للركبتين في الطفولة المبكرة ولتحديد الأسباب الشائعة له ولتقييم نتائج تطوره. المرضى والطريقة: ضمت الدراسة 213 طفلا مصابين بالانحراف الإنسي للركبتين في الطفولة المبكرة من مرضى العيادة الاستشارية لجراحة العظام في المستشفى الجمهوري التعليمي. تم قياس المسافة بين الركبتين كل ستة أشهر خلال فترة المتابعة التي تراوحت بين 2 – 6 سنوات.النتائج: إن السبب الأكثر شيوعا للانحراف الإنسي للركبتين في الطفولة المبكرة كان النوع الفسلجي وظهر في 153 طفلا وكان معدل المسافة بين الركبتين هو 3.4 سم، ويتصصح ذاتيا خلال سنتين من المتابعة. كان مرض الكساح التغذوي هو السبب الثاني وظهر في 58 مريضا، وقد شفي خلال أربعة سنوات. كما كان السبب الأقل شيوعا هو الكساح المقاوم (حالتين فقط). الخلاصة: إن السبب الأكثر شيوعا للانحراف الإنسي للركبتين في الطفولة المبكرة هو النوع الفسلجي والذي يتشافى تماما في نهاية السنة الرابعة من العمر. كان الكساح التغذوي هو السبب الثاني والذي يؤدي الى إنحراف أشد ويحتاج الى فترة أطول للشفاء.

Keywords

Knee --- genu varus --- bilateral --- children

Listing 1 - 10 of 69 << page
of 7
>>
Sort by
Narrow your search

Resource type

article (69)


Language

English (43)

Arabic and English (11)

Arabic (8)


Year
From To Submit

2019 (5)

2018 (7)

2017 (6)

2016 (9)

2015 (5)

More...