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Article
The Role of Garlic Extract on the Effect of Organic Pesticides on Murine Liver Cells

Author: Khalid Hamdan Gathwn
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2006 Volume: 5 Issue: 3 Pages: 344-350
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACK GROUND:Organic phosphorus pesticides are most widely preferred pesticides, and know to have detrimental effect on various living organisms.METHODS:Twenty four male Balb/c mice were used. These were divided into four group (1,2,3,4) . Chlorpyriphos was given orally on alternate days by garage (20mg/kg body weight), aqueous garlic alone was given orally daily by garage (200mg/kg body weight, while garlic extract followed by chlorphriphos was also given.RESULTS:Lipid peroxidation (LPO) was measured in liver homogenate . The extent of LPO was significantly increased in animals treated with pesticide while non-significant result were obtained with garlic extract alone . Pretreatment with garlic followed by pesticide showed similar values. The levels of glutathione and total thiol was significantly decreased in animals treated with pesticide and non- significant with garlic . pretreatment with garlic followed by pesticide showed similar value. The free radical scavenging enzyme like SOD , as well as GSH- dependent enzyme (GPx, GST and GR) show significant decrease in animals treated with pesticide and non-significant with garlic. Pretreatment with garlic followed by pesticide showed similar to that of control.CONCLUSION:Pesticide exposure could be prevented by Co-administration of garlic extract.


Article
Effect Of Selenium on Antioxidant Enzymes and Content of Photosynthetic Pigments in algae Chlorococcum littorale Chihara,Nakayama &Inouye

Authors: Suaad H. Ali Al - Badri --- Abdul –Wahab Resan AL - Ebady
Journal: Univesity of Thi-Qar Journal مجلة جامعة ذي قار العلمية ISSN: 66291818 Year: 2018 Volume: 13 Issue: 3 Pages: 42-56
Publisher: Thi-Qar University جامعة ذي قار

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Abstract

The study provides a new insight into the impact of Se on green algae Chlorocouyeoccum littorale and effects of Se on antioxidant system and bioaccumulation. Se positively promoted C. littorale growth at lower concentrations (≤50 mg L−1), acting as an antioxidant through the inhibition of lipid peroxidation (LPO) and intracellular reactive oxygen species (ROS). The antioxidative effect was associated with an increase in guaiacol peroxidase (GPX), catalase (CAT), superoxide dismutase (SOD) and photosynthetic pigments. Meanwhile, significant increase in the cell growth rate and organic Se content was also detected in the algae

Keywords

Chlorocooccum --- Selenium --- LPO --- ROS --- GPX --- CAT.

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