research centers


Search results: Found 35

Listing 1 - 10 of 35 << page
of 4
>>
Sort by

Article
6- A STUDY OF THE INCIDENCE OF BONE MARROW NECROSIS IN PRIMARY & SECONDARY MALIGNANT BONE TUMORS 32 ,

Authors: MUHAMMED B NFAWA --- AMMAR ABDUL-MUHSIN --- ZUHAIR AL-BARAZANCHI
Journal: Basrah Journal of Surgery مجلة البصرة الجراحية ISSN: 16833589 / ONLINE 2409501X Year: 2009 Volume: 15 Issue: 1 Pages: 32-42
Publisher: Basrah University جامعة البصرة

Loading...
Loading...
Abstract

During one year period, 21 newly diagnosed patients with different malignant bone tumors weresubjected to this study, 52.4% (11) of them were males & 47.6% (10) were females with a meanage of 50.2 years. Detailed history & physical examination were taken including the age, sex,the pathological type of the tumor, whether it is a primary or secondary & the site of the tumor,the existence of bone pain, fever, weight loss, pallor, pathological fractures, neurological deficit,any adjuvant treatment the patient had been put on, the existence of sickle cell disease, diabetesmellitus and any history of a previous surgery. All cases were subjected to the followingtests: complete blood count (CBC) including the estimation of erythrocyte sedimentation rate(ESR) & reticulocyte count, estimation of lactate dehydrogenase(LDH) & alkaline phosphatase(ALP) enzymes & serum calcium. All cases were subjected to bone marrow examination includingboth aspirate & trephine biopsy (with its touch imprint). Smears & sections were examinedthoroughly to assess marrow status with emphasis on the existence of bone marrow necrosis(BMN).Results showed that 19.1 % of cases had bone marrow necrosis. Their mean age was 50.25years, with equal sex distribution, half of them had primary tumors, and 75 % of them had theirtumors situated in the spine. Clinically: all of them had weight loss, fever & bone pain while 75% of them had pathological fractures. The mean values of the investigations done for themwere: Hb 94 g/L, PCV 0.29, reticulocyte count 2.43 %, WBCs 14.75 x 109/L. Peripheral bloodfilm for all showed leuco-erythroblastic picture. They showed an elevated mean serum LDH(307.50 IU/L) & ALP (116.06 IU/L) levels.Cases that showed no evidence of BMN constituted 80.9 % of total. They had a mean age of5.15 years. 52.9 % were males while 47.1 % were females. Just more than half of cases (52.9%) had primary while 47.1 % had secondary type of tumors & 47.05 % of them were located inthe spine. Clinically all of them had bone pain, 94.1 % had weight loss, 52.9 % pathological fractures,29.4 % pallor & 23.5 % had fever. Their mean laboratory values were: Hb 108.1 g/L, PCV0.33 %, reticulocyte count 1.36 %, WBCs 7.11 X 109/L, LDH 214.88 IU/L, ALP 83.48 IU/L.Comparative study between cases with BMN & those without showed a significant relationshipbetween the following parameters & the presence of BMN at a level (p<0.05): fever, leukocytosis,reticulocytosis, and high LDH levels. These results were comparable with some & contradictingwith other studies.The paucity of studies in this field created difficulties to relate the results of this study to others,especially in our Country. Further studies in the same field will probably clarify.In conclusion, bone marrow necrosis, is not uncommon among primary & secondary malignantbone tumors. It is associated with severe clinical-pathological features that may reflect a pooroutcome. Prolonged, follow up studies are in need to clarify this point.

Keywords

MARROW --- MALIGNANT --- BONE


Article
CLINICAL AND HISTOPATHOLOGICAL STUDY OF MAMMARY TUMORS IN FOREIGN DOGS BREEDS IN KURDISTAN REGION OF IRAQ.
دراسة سريرية ونسيجية مرضية لأورام الغدة اللبنية في اناث الكلاب في منطقة كردستان العراق

Loading...
Loading...
Abstract

Mammary tumors in five intact bitches were evaluated at the Department of Medical Science, Faculty of Veterinary Medicine, Duhok University. Information about the breed and age of the animals, location and number of affected mammary glands, surgical outcome, tumor recurrence and survival were recorded. All the removed tumors were histologically examined and diagnosed as malignant types.

تضمنت الدراسة تقيم حالات أورام الغدد اللبنية في خمس من أناث الكلاب أحيلت ألى فرع العلوم الطبيه/ هيئة العلوم البيطرية / جامعة دهوك. تم تسجيل نوع و أعمار الحيوانات وموقع الغدد المصابه و عددها. أستئصلت الأورام جراحيا" و تم متابعة الحيوانات وتسجيل ظهور الورم وفترة بقاء الحيوانات حية بعد أزالة الأورام. فحصت كل الأورام المستأصلة نسيجيا" لتحديد أنواعها.

Keywords

Tumors --- Dogs --- Malignant


Article
Malignant features of Meningioma CT scan Study.

Author: Ali K. AL-Shalchy
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2010 Volume: 52 Issue: 3 Pages: 266-267
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

CT scan features of Malignant Meningioma
Objective: Meningioma which is a common benign Brain tumor can be malignant, but the final decision is by biopsy. However CT. Scan features can help to evaluate malignancy of a lesion. The aim of this retrospective study is to look for the malignant features of a malignant meningioma .
Patients and Methods: This is a retrospective study of 50 malignant meningiomas in the neuro-surgical unit in the specialized surgical hospital (previously AL-Shaheed Adnan hospital), for the period from March 1992 to March 2007. We search specially for Malignant features on the CT scan study of the patients.
Results: 94%of the patients had different features of malignant meningioma, only 6% CT scan did not show any malignant features, we also evaluated the results of surgery .
Conclusion: CT scan is one of the most important diagnostic procedures for diagnosis of brain tumor; however final diagnosis can only be emphasized by the histo-pathological studies.


Article
CLINICAL STUDY OF MALIGNANT LYMPHOMAS IN DUHOK: A CASE SERIES STUDY DURING 2007-2013
دراسة سريرية للمفوما الخبيثة فى دهوك : دراسة حالات متتالية للفترة من 2007-2013

Author: ABID M. HASSAN عبيد حسن
Journal: Duhok Medical Journal مجلة دهوك الطبية ISSN: ISSN: 20717334 (online)/ ISSN: 20717326 (Print) Year: 2014 Volume: 8 Issue: 1 Pages: 34-41
Publisher: University of Dohuk جامعة دهوك

Loading...
Loading...
Abstract

ABSTRACTBackground and Objectives Earlier studies have addressed the pathological classification ofmalignant lymphomas in Duhok, while no studies have addressed the clinical aspects andoutcome of treatment.Aim to identify clinical features, diagnostic procedures, standard treatment and outcome ofmalignant lymphomas in DuhokMaterial and Methods This is a case series study of 108 initially untreated patients withmalignant lymphoma who were followed during the period 2007 to 2013.Results The 108 enrolled patients included 61 patients with Non-Hodgkin’s Lymphoma(NHL) and 47 with Hodgkin’s Lymphoma (HL).The median age of patients with NHL was52 (48.4±22.5) years while that of patients with HL was 29 (34.4±16.4) years. The principalclinical presentation was cervical lymphadenopathy; 38% in NHL and 70% in HL. Bsymptomswere present in 20% of NHL patients and 32% of HL patients. The staging ofpatients with NHL showed that they were mostly in stages III and IV, while patients with HLwere mostly in stage II. Bone marrow involvement was found in 35% of patients with NHLand in 3% of patients with HL. The standard treatment for NHL was protocol R-CHOP, givenevery 21 days; each patient received an average of 8 cycles. For HL, the standard treatmentwas the ABVD protocol given in an average of 6 cycles. Of all the patients with NHL, eighthad relapse and were put on second line therapy (ICE protocol) while four died frominfections. Of the patients with HL, two had relapsed and one died from infection.Conclusion The NHL in the studied patients was characterized by a severe course andmultiorgan involvement, and stage III and IV were the main presenting stages at diagnosis.The high rates of marrow involvement, extranodal involvement and advanced clinical stagesin NHL as compared to HL, which are shared by previous studies worldwide, explain its lessfavourable outcomes as shown by the current study.

خلفية وأهداف الد ا رسة: أجريت د ا رسات سابقة حول تقسيم أنواع اللمفوما الخبيثة في دهوك ولكن لا توجد د ا رسات حول الأع ا رض السريرية ونتائج العلاج. تهدف الد ا رسة إلى تحديد الأع ا رض السريرية وطرق التشخيص والعلاج ونتائجه للمفوما الخبيثة في دهوك.طرق البحث:@هذه الد ا رسة اجريت على سلسلة من الحالات المرضية المصابة بسرطان الغدد اللمفاوية وعددهم ١٠٨ حالة .٢٠١٣- من البداية قبل العلاج، تم متابعتهم خلال فترة ٢٠٠٧ و ٤٧ (NHL) ( النتائج: أظهرت د ا رسة ( ١٠٨ ) حالة من اللمفوما الخبيثة وجود ٦١ حاله كانوا مصابين ب(ننهوجكن لمفوما معدل العمر لننهوجكن لمفوما هو ٣٥ سنة ولكن لمرضى هوجكن لمفوما هو ٣٠ . (HL) حالة مصابين بهوحكن لمفوما سنة. النوع الاكثر شائع النسيجي لننهوجكن لمفوما هو الدرجة الوسطية والأكثر شائع هو الخلايا الكبيرة المنتشرة ولكن لهوجكن لمفوما هو الخلاىا المختلطة . الاع ا رض الرئيسية هو تضخم العقد اللمفاوية العنقية بنسبة ٣٨ % لننهوجكن موجودة بنسبة ٢٠ % لمرضى ننهوحكن و ٣٢ % لمرضى هوجكن (B-SYMPTOM) و ٧٠ %لهوجكن لمفوما. الاع ا رض لمفوما. م ا رحل مرضى ننهوجكن لمفوما على الاكثركانوا في المرحلة الثالثة وال ا ربعة ولكن مرضى هوجكن لمفوما علىالاكثر في المرحلة الثانية. انتشار المرض في النخاع العظمي لمرضى ننهوجكن لمفوما ٣٢ % ولكن لمرضى هوجكنكل ٢١ يوما جرعة وعددالجرعات الكلية ،(R-CHOP) كان بنسبة ٣%. العلاج الرئيسي لمرض ننهوجكن لمفوما بدأتوأعطيت ٦ دو ا رت وكل دورة جرعتان، جرعة في (ABVD) ٨ جرعة. ولكن لمرضى هوجكن لمفوما العلاج الاساسي بدأت اليوم الاول وجرعة في اليوم ال ا ربع عشر. كانت النتيجة ٨ مرضى ننهوجكن، المرض عاد واعطيت علاج ثاني ولكن ٤ مرضى توفى نتيجة الالتهابات المعدية. أما مرضى هوجكن , عاد المرض في حالتين، واحد المرضى منهم توفي نتيجة الالتهابات.الاستنتاجات: إن مرضى ال(ننهوجكن ليمفوما) كانوا يعانون من شدة المرض ومن إصابة عدة أعضاء وكانت لدرجةالثالثة وال ا ربعة أكثر الدرجات شيوعاً لدى التشخيص. إن النسبة العالية لإصابة نخاع العظم وإصابات خارج الغددوالأع ا رض السريرية الشديدة في مرضى ال(ننهوجكن) مقارنة بمرضى الهوجكن كانت السبب في النتائج غير الواعدة وكما ظهر في د ا رسات مشابهة أخرى.


Article
A Clinical-Hematological Study of Pancytopenia Patients Attending Nanakaly Hospital in Erbil City

Authors: Alan Isaac Isho --- Nawsherwan Sadiq Mohammad
Journal: Iraq Joural of Hematology المجلة العراقية لامراض الدم ISSN: 20728069/25432702 Year: 2016 Volume: 5 Issue: 1 Pages: 129-142
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract

Background: Pancytopenia is a triad of low hemoglobin, white blood cells and platelets.Although it is a common clinical problem with an extensive differential diagnosis, there is arelatively little discussion of this abnormality in major textbooks of internal medicine andhematology.Objectives: This study aimed to determines the etiology and clinical profile of pancytopenicpatients attending Nanakaly hospital.Materials and Methods: During a period of 6 months, 60 pancytopenic patients attendedNanakaly hospital, their ages ranged between one-81years. A control group of 50 age-matchedapparently healthy person were tested for complete blood picture and reticulocyte count. History,physical examination and hematological parameters at presentation were recorded. Hematologicalprofile included hemoglobin, total and differential leukocyte count, platelet count, reticulocytecount, peripheral blood and marrow smears together with marrow biopsy were assessed.Pancytopenic cancer patients on chemotherapy were excluded. Pancytopenia was defined ashemoglobin less than 10g/dl, WBC less than 4 x109/L and platelet count less than 150 x 109/L.Results: The mean Hb concentration, WBC count and platelet count in studied group weresignificantly lower than in control group. Hematological malignancies were the commonest causeof pancytopenia and accounted for (51.7%), they included: Acute leukemia (35%),myelodysplastic syndrome (11.7%), hairy cell leukemia (3.3%) and myelofibrosis (1.7%). Aplastic and megaloblastic anemia each of them accounted for (16.7%), hypersplenism wasresponsible for (10%). Other less common causes included enteric fever, kalaazar and secondarymetastasis each of them accounted for (1.7%). Pallor was present in every case. Fever was presentin (63.3%) and (25%) had bleeding manifestations at the time of presentation Conclusions: The most common causes of pancytopenia were acute Leukemia, aplastic anemiaand Megaloblastic anaemia, but rare causes like myelofibrosis, enteric fever, kala azar andsecondary metastasis should also be kept in mind.


Article
Identification of cryptosporidium among immunocompromised indviduals

Authors: Nihad S. S. AL-Sherefat نهاد صبحي الشريفات --- Abdul-Salam M. Al-Mukhtar عبد السلام المختار
Journal: Annals of the College of Medicine Mosul مجلة طب الموصل ISSN: 00271446 23096217 Year: 2005 Volume: 31 Issue: 2 Pages: 83-86
Publisher: Mosul University جامعة الموصل

Loading...
Loading...
Abstract

Objective: to investigate the occurrence of cryptosporidium oocyst in patients with malignant disease before and after receiving chemotherapy.
Methods: A follow up study of 107 patients before and after 2-3 months from receiving chemotherapy compared with 100 healthy subjects studied as a control.
Results:
1.The study revealed a significant increase of cryptosporidium oocyst (18.37%) in patients after receiving chemotheropy in comparison with (8.39%) in patients before receiving chemotherapy and (5%) in control group.
2.In our study we used lodine stain with simple modification by using the oil immersion power for the diagnosis and in this case we obtained excellent diagnosis for Cryptosporidium oocyst. This modification has been used for the first time for better diagnosis of cryptosporidium oocysts.

Key word: Cryptosporidiosis, patients with malignant disease, Mosul city.


Article
Malignant tumours of nasal cavity and paranasal sinuses in north of lraq a fifteen years retrospective study

Authors: Q Radwan قحطان رضوان --- Daoud S. Allos داود الوس
Journal: Annals of the College of Medicine Mosul مجلة طب الموصل ISSN: 00271446 23096217 Year: 2005 Volume: 31 Issue: 1 Pages: 17-21
Publisher: Mosul University جامعة الموصل

Loading...
Loading...
Abstract

Objectives: To identify the different pathological types of malignant tumors of nasal cavity' and paranasal sinuses, their different clinical aspects, treatment received and prognosis in north of Iraq.Design : Retrospective study.Settings: Files of patients treated in the hospital of oncology and nuclear medicine in Mosulover 15 years period (1980-1994).Main outcome measures: Types, incidence, age and sex distribution, anatomical sites, clinical presentation, staging, method of treatment and prognosis.Results: They constituted 0.51% of all malignancies and 2.13 % of head and neck cancers.Sinus tumours affected both sexes equally as well as both sides. Nasal cavity tumours weremore common in male (male/female=1.4/1) and in the right side (right/left=1.33/1).Thecommonest age at presentation was the fifth decade.The most common presenting symptom was facial and nasal pain with average delay indiagnosis of about 8.5 months. Tumours of epithelial origin formed the majority ofcases (85.68%).All maxillary and ethmoidal cases were advanced at time of diagnosis (T3 or T4), while 60%of nasal cavity tumours were T1 and T2. 21.87% of patients had palpable cervical lymph nodes at presentation.The majority of patients received radiotherapy alone, few cases had surgery alone or both, but prognosis was generally unsatisfactoryconclusion: Malignant tumours of nose and sinuses are rare in north of lraq, are usuallyadvanced at presention , and carry poor prognosis.keywords: Malignant Tumours , Nasal Cavity , Paranasal Sinuses


Article
Malignant Gastrointestinal Stromal Tumors of the Stomach

Author: Zuhair Raof Al-Bahrani
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2008 Volume: 7 Issue: 3 Pages: 196-200
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

ABSTRACT:BACKGROUND:Stromal or mesenchymal neoplasms affecting the gastrointestinal (GI) tract are divided into two groups. The less common variety includes tumors that are identical to those that arise in the soft tissues throughout the rest of the body, including lipomas, schwannomas, hemangiomas. The second more common group consists of stromal tumors that are collectively referred to as gastrointestinal stromal tumors (GISTs).They are most often located in the stomach and proximal small intestine.OBJECTIVE:To compare the incidence, mode of presentation and management of malignant gastric GISTs of this study from Iraq with other world reports.METHODS:Retrospective study of the medical records of 1037 patients with gastric malignancies operated upon between January 1970-December 2000 were reviewed. The incidence of GISTs , their age and sex, symptomatology, diagnostic procedures, surgical management and results will be presented.RESULTS:Among 1037 patients with gastric malignancies, 13 (1.25%) were malignant GISTs. 6 were males and 7 females. Age ranges from 19-67 (median 58 +/- 13 .2397 SD) years. Mode of presentation were; upper GI bleeding 8(62%), dyspepsia 4(31%) and mass one (8%) patient. Duration of illness ranges from 2 days-8 years (median 3 months+/- 25.9207 SD ). Barium study revealed a tumor in 10 out of 11 patients. Endoscopy in 12 patients reported 4 nodular, 3 fungating and 3 ulcerative tumor and two normal. Ultrasound in 8 patients showed a mass in 7(5 intraluminal, two extraluminal) and no tumor in one. Site of tumor were the; lesser curve 4(31%), antrum 3(23%), greater curve 2(15%), fundus 2(15%), body one (8%) and cardia one (8%) patient. Grossly the tumors were; fungating 5, nodular 2, ulcerative one, nodular-cystic 3 and nodular-ulcerative in 2. The tumor size vary from 5x3 – 17x12 (mean 9.69231 +/- 3.727793 SD x 7.69231 +/- 2.95479 SD) cm.Gastric resections were; upper 5, segmental 4, subtotal 2 and lower 2 patients. Chemotherapy and/or radiotherapy were given to advance or those with metastasis. Histopathology reported low-grade malignancy in 5 and high-grade in 8 patients. According unified 1997 TNM staging were; I 2, II 4, III 3 and IV 4 cases. Two-years survival was 69% (9 out of 13) and 5-years was 46% (6 out of 13). CONCLUSION:Malignant GISTs constitute 1.25 % of all gastric malignancies. No gender predilection found. Median age 50.3 years. Recurrent upper GI bleeding in 62% and dyspepsia in 31%. No specific symptoms but abdominal mass in 4 cases. Barium study, endoscopy and US were the diagnostic procedures. Tumors were; mostly intraluminal, fungating nodular and large (median 8x8 cm). Resection was the treatment. 5 were low-grade and 8 high-grade malignancy. 2 and 5-years survival were 62% and 46% respectively.


Article
Prospective analysis of 300 cases of ovarian cysts in Iraqi women

Author: Tlefih A. J. *
Journal: Karbala Journal of Medicine مجلة كربلاء الطبية ISSN: 19905483 Year: 2007 Volume: 1 no.3 Issue: 2 Pages: 203-210
Publisher: Kerbala University جامعة كربلاء

Loading...
Loading...
Abstract

ackground: Most ovarian cysts (O C) are functional, benign, harmless, and may disappear on theirown within a few months. However, they may twist, rupture, bleed, or press on the surroundingorgans. It may be difficult to differentiate malignant O Cs from the benign unless histopathological examis performed. There are many methods for treatment of O Cs.Objectives: The aim of this study is to know the prevalence of O Cs, and to study their types,presentation, and treatment.Methods: Over a 5 year period, from Feb. 2000 to Jan. 2005, a prospective study of 300 women with OCs was carried out in 3 hospitals in Baghdad (Al - Habeabia hospital, Al - Elweya teaching hospital andAl - Kindy teaching hospital).Results: The highest incidence of O C (35%) was among women aged 21 - 30 years. The functional O Cwas the most common type (64.7%), and (31%) of them showed spontaneous resolution. (68.3%) of O Cswere singular.(60%) of O Cs were symptomatic, and lower abdominal pain or discomfort was the most commonsymptom (91.7%). (75%) of cases were treated surgically and cystectomy was the most common surgicalprocedure that was adopted in this study (72.9 %).(2.7%) of women had malignant O Cs. Out of them (75%) were at advanced stage (III or IV), and (87.5%)were postmenopausal.Conclusion: Most of the O Cs were benign or functional, symptomatic and some may disappear withouttreatment, but surgery was the main treatment. The highest incidence of O C was among women aged 21 -30 years. Most malignant O Cs were at advanced stage (III or IV).


Article
Discrimination of Malignant from Acute Benign Compression Spinal Fractures with Magnetic Resonance imaging

Author: Nadia Hassan Ali ALSalihi (FICMS) ( diag. rad)
Journal: Al-Kindy College Medical Journal مجلة كلية الطب الكندي ISSN: 18109543 Year: 2014 Volume: 10 Issue: 1 Pages: 11-17
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Differentiation between malignant and benign vertebral compression fracture is often problematic. This is precisely difficult in elderly who are predisposed to benign compression caused by osteoporosis .Establishing correct diagnosis is of great importance in determining the treatment andprognosis.A study was performed to determine which magnetic resonance imaging findings are useful in discrimination between metastatic and acute osteoporotic compression fractures of the spine. Recently MRI is being increasingly used for evaluation of these fractures.Objectives: The aim of this study is to establish the correct diagnosis of malignant and benign compression vertebral fracture by MRI to determine treatment and prognosis.Methods: MRI of (45 )patients with vertebral compression fracture who underwent MRI of spine during 2 years period ( 2004-2006) in Neuro surgical hospital were retrospectively reviewed by an expedient radiologist , A collapsed vertebra were considered to be acute if there was recent history of back pain of less than 3moths. All MRI sequences needed for spine examination was done( T1WI SE, T2WI GE STIR, and Mylography ) and Gadolinium contrast medium was given to all patients..Results: Of total 45 patients (31male, 14 female, their age range between 18-72years) , The criteria used to differentiate between benign andmalignant collapse spine on MRI was based on the signal intensity, morphology and contrast enhancement for the correct diagnosis. Homogenous and diffuse abnormal signal intensity, posterior convexity and involvement of pedicles are sign that are strongly suggestive of malignant collapse .Conversely, a band like area of low signal intensity adjacent to depressed end plateand preservation of signal intensity of vertebra suggest benign nature of the collapse.Conclusions: We found that MRI features is helpful in differentiation of malignant and benign compression fractures in majority of cases, and if initial MRI finding are equivocal correlation with other images technique, follow up and biopsy in selected cases helpful in arriving correct diagnosis.

Listing 1 - 10 of 35 << page
of 4
>>
Sort by
Narrow your search

Resource type

article (35)


Language

English (30)

Arabic and English (5)


Year
From To Submit

2018 (2)

2017 (5)

2016 (3)

2015 (3)

2014 (4)

More...