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Article
The impact of the presence of Porphyromonas gingivalis on periodontal health in a group of patients with periodontitis in Erbil
تأثير وجود بPorphyromonas gingivalis على صحة اللثة في مجموعة من المرضى المصابين بالتهاب اللثة في أربيل

Authors: Solav Abdulqadir Mustafa --- Ashti Mohammad Amin --- Sazan Moffaq Abdulaziz
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2015 Volume: 19 Issue: 3 Pages: 1069-1074
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objective: Chronic periodontitis is the destruction of the tooth supporting structures as a result of a complex interaction between bacteria colonizing the gingival crevice and host’s immune responses. Porphyromonas gingivalis is one of the main periodontopathogens with multiple virulence factors. The aim of this study was to investigate the detection rate of Porphyromonas gingivalis in chronic periodontitis patients versus healthy subjects using PCR assay, and its association with increased pocket depth and clinical attachment loss.Methods: Seventy subjects (35 patients with chronic periodontitis and 35 healthy subjects) meeting the inclusion criteria of this study were selected. All the subjects were clinically assessed for probing pocket depth and clinical attachment loss then subgingival microbial samples were collected using sterile paper points and analyzed for the presence of Porphyromonas gingivalis using polymerase chain reaction assay. Results: A significant difference in Porphyromonas gingivalis detection rate between chronic periodontitis and healthy groups was recorded. Porphyromonas gingivalis was significantly associated with deep pockets. The detection rate increased with the increase in the severity of the disease, although, this correlation was not statistically significant.Conclusion: A positive association was observed between Porphyromonas gingivalis and increased pocket depth. The recovery rate was higher in severe cases.

Keywords

CAL --- chronic periodontitis --- PCR --- P. gingivalis --- PPD


Article
The speed of eating and functional dyspepsia
سرعة الأكل وعسر الهضم الوظيفي

Author: Khalid A. Jasim Al-Khazraji* CABM, FRCP, FACP MD د. خالد الخزرجي
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2016 Volume: 58 Issue: 4 Pages: 348-353
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: dyspepsia is a common complaint, affecting about 26-41% of the general population. Investigations fail to identify organic cause in 50%–60% of functional dyspepsia. Little informations are available about whether quick eating is one of the risk factors for functional dyspepsia (FD).Objectives: To study the association between quick eating and FD.Materials and methods: The study was performed on 132 resident doctors in the medical city/Baghdad, by introducing a questionnaire derived from the Rome III criteria for diagnosis of FD and its subtypes and calculating the average daily meal duration for each one. The subjects were all Arabian, Iraqi, white resident doctors sharing the same type and amount of food. We excluded those with history of alcoholism, chronic NSAID use, documented organic gastrointestinal lesion, or with alarm features of dyspepsia , chronic systemic disease or previous history of dyspepsia.Results: The prevalence of uninvestigated dyspepsia (UD) was 37.88%, post-prandial distress syndrome (PPD): 16.67%, and epigastria pain syndrome (EPS):12.12%.Quick eating (independently on the BMI) was significantly associated with higher prevalence of FD and EPS, but not PPD. Higher BMI was associated with higher prevalence of FD and PPD (not EPS), smoking was associated with higher prevalence of FD and both subtypes, while age and gender had no effect on the prevalence of each.Conclusion: prevalence of UD increases in quick eaters regardless the BMI, Smoking and higher BMI also increase the UD prevalence.Key words: functional dyspepsia, uninvestigated dyspepsia, speed of eating, PPD, EPS.

الخلاصة:المقدمة: عسر الهضم هو شكوى شائعة، تؤثر على حوالي 26-41٪ من عموم السكان. فشلت التحقيقات لتحديد سبب عضوي في 50٪ -60٪ من عسر الهضم الوظيفي. تتوفر معلومات قليلة حول ما إذا كان تناول الطعام بشكل سريع هو واحد من عوامل الخطر لعسر الهضم الوظيفي.الهدف من الدراسة: دراسة العلاقة بين تناول الطعام بسرعة وعسر الهضم الوظيفي.المواد وطرق الدراسة: تم إجراء الدراسة على 132 من الأطباء المقيمين في مدينة الطب / بغداد ، من خلال طرح استبيان مستمدة من معايير روما III لتشخيص عسر الهضم الوظيفي وفروعه ، وحساب متوسط مدة الوجبة اليومية لكل واحد. جميع الاشخاص كانوا عرب، عراقيين، بيض، اطباء مقيمين تشاركوا نفس النوع والكمية من المواد الغذائية. استبعدنا من لديه تاريخ من الإدمان على الكحول، واستخدام الأدوية اللاستيرودية المضادة للالتهاب ، وافات الجهاز الهضمي العضوية الموثقه، أو مع مؤشرات الإنذار لعسر الهضم، أمراض جهازية مزمنة أو تاريخ سابق من عسر الهضم.النتائج: كان انتشار سوء الهضم غير المتحقق منه 37.88% ، متلازمة ضوائق بعد الطعام 16.67% ومتلازمة الالم المعدي 12.12٪. سرعة الأكل (مستقل عن مؤشر كتلة الجسم) مرتبط بشكل واضح مع ارتفاع الانتشار لعسر الهضم الوظيفي ومتلازمة الالم المعدي وليس متلازمة ضوائق بعد الطعام، مؤشر كتلة الجسم العالي مرتبط مع انتشار عالي لعسر الهضم الوظيفي و متلازمة ضوائق بعد الطعام وليس متلازمة الالم المعدي ، وارتبط التدخين مع ارتفاع معدل انتشار سوء الهضم الوظيفي وكلا فرعية، في حين أن العمر والجنس ليس له تأثير على انتشار لكل منهما.الاستنتاجات: انتشار سوء الهضم غير المتحقق منه يزداد في الاشخاص سريعي الاكل بغض النظر عن مؤشر كتلة الجسم ، التدخين وارتفاع مؤشر كتلة الجسم أيضا يزيد انتشار سوء الهضم غير المتحقق منه.الكلمات الرئيسية: عسر الهضم الوظيفي، وسوء الهضم غير التحقيق منه، وسرعة الأكل، ومتلازمة الالم المعدي ، متلازمة ضوائق بعد الطعام.


Article
Evaluation of serum anti-cyclic citrullinated peptide antibodies level in rheumatoid patients with and without periodontitis

Author: Fatin M. Jarallah فاتن جار الله
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2012 Volume: 24 Issue: 4 Pages: 83-87
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Rheumatoid arthritis (RA) and periodontitis (PD) are widely prevalent diseases and are characterized bytissue destruction due to chronic inflammation. Recently, there is growing evidence that the two diseases sharemany pathological features. An association between periodontitis and rheumatoid arthritis has been consideredmany years ago. The current study was established to evaluate the serum ACCP levels in rheumatoid arthritis patientswith and without periodontitis, in addition to study the correlation between serum ACCP levels and periodontalparameters.Subjects and methods: A total of 95 subjects were enrolled in this study, age ranged (35 – 55) years divided into 3groups: Group I consist of 45 rheumatoid arthritis patients with periodontitis, while group II consist of 35 rheumatoidarthritis patients without periodontitis and group ÉÉÉ which consist of 15 apparently- healthy controls. . Periodontalparameters used in this study were plaque index (PI), gingival index (GI), probing pocket depth (PPD), clinicalattachment level (CAL) and bleeding on probing (BOP). Blood samples were collected from each subject todetermine serum concentrations of ACCP by means of enzyme-linked immune-sorbent assay (ELISA).Results: present study revealed that serum ACCP levels were significantly higher in rheumatoid patients withperiodontitis (P<0.001) than that in other two groups. Regarding the correlation between serum ACCP levels andperiodontal parameters, the current study showed positive correlation between serum ACCP and each of plaqueindex, gingival index and probing pocket depth.Conclusion: The current results provide strong evidence of association between periodontitis and rheumatoid arthritis,and suggested that periodontitis may play an important role in activation and triggering immune response

Keywords

Background: Rheumatoid arthritis --- RA and periodontitis --- PD are widely prevalent diseases and are characterized by tissue destruction due to chronic inflammation. Recently --- there is growing evidence that the two diseases share many pathological features. An association between periodontitis and rheumatoid arthritis has been considered many years ago. The current study was established to evaluate the serum ACCP levels in rheumatoid arthritis patients with and without periodontitis --- in addition to study the correlation between serum ACCP levels and periodontal parameters. Subjects and methods: A total of 95 subjects were enrolled in this study --- age ranged --- 35 – 55 years divided into 3 groups: Group I consist of 45 rheumatoid arthritis patients with periodontitis --- while group II consist of 35 rheumatoid arthritis patients without periodontitis and group ÉÉÉ which consist of 15 apparently- healthy controls. . Periodontal parameters used in this study were plaque index --- PI --- gingival index --- GI --- probing pocket depth --- PPD --- clinical attachment level --- CAL and bleeding on probing --- BOP. Blood samples were collected from each subject to determine serum concentrations of ACCP by means of enzyme-linked immune-sorbent assay --- ELISA. Results: present study revealed that serum ACCP levels were significantly higher in rheumatoid patients with periodontitis --- P<0.001 than that in other two groups. Regarding the correlation between serum ACCP levels and periodontal parameters --- the current study showed positive correlation between serum ACCP and each of plaque index --- gingival index and probing pocket depth. Conclusion: The current results provide strong evidence of association between periodontitis and rheumatoid arthritis --- and suggested that periodontitis may play an important role in activation and triggering immune response

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