ackground: Thrombocytopenia is low platelets count which is either due to defective platelet production (hypo-productive thrombocytopenia) or due to increased platelet breakdown (hyper-destructive thrombocytopenia). Measurement of platelet counts alone do not explain the underlying patho-mechanism of thrombocytopenia.. Recent advances in automated blood cell analyzers facilitate the measurement of several blood cell parameters automatically such as, platelet indices including mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT) and these parameters could provide some important clinical information.Aim of the study: to investigate whether platelet indices( MPV,PDW,PCT) could serve as diagnostic tools in the differential diagnosis of thrombocytopenia and, if there is any correlation between platelet count and platelets indices .Subjects and Methods: A total of 77 Iraqi patients (28 males and 49 females) with thrombocytopenia were subjected to the following tests:1. Complete blood count using Mindway haematologic autoanalyser.2. Peripheral blood film .3. Bone marrow aspirate with bone marrow trephine biopsy when indicated.A group of 50 healthy person (age & sex matched) were included as a controlResults: hyper-destructive thrombocytopenia (immune thrombocytopenia) representing 12.9% of total patients, while hypo-productive thrombocytopenia due to various causes representing 87.1% of total patients. The MPV, PDW are significantly higher in immune thrombocytopenia group as compared with thrombocytopenia of hypo-productive patho-mechanism and there were no correlations between platelets count and both MPV and PDW in hyper-destructive and hypo-productive thrombocytopenia but there was a direct correlation between platelet count and PCT .Conclusion: Platelet indices provide plenty of clinical information about the causes and patho-mechanism of thrombocytopenia and could be helpful tests to distinguish hyper-destructive thrombocytopenia from hypo-productive thrombocytopenia easily, so more interest for the use of these indices in differential diagnosis of thrombocytopenia is required.

platelet indices --- platelet count --- thrombocytopenia.

Background: Preeclampsia (PE) is a pregnancy specific syndrome that affects 6–8% of pregnancies worldwide. The specific pathogenesis of preeclampsia remains incompletely elucidated. Many tests have attempted to establish the diagnosis of preeclampsia as early as possible, often even before the patients develop arterial hypertension.Objective: This study aims to identify whether the platelet indices and fibrinogen level are significantly affected by preeclampsia compared to normal pregnancy Patients and methods :This retrospective case-control study was done in AL- Batool Teaching Hospital-Department of Obstetrics and Gynecology, from the 1st of September 2014 to 30th of September 2015 , 75 woman who fulfill the inclusion criteria were included in the study , they were divided into two groups 25 pregnant woman with preeclampsia & 50 normal pregnant woman as control group(were all normotensive pregnant woman with single intrauterine gestation and the obstetric history is uneventful ) . Results: Systolic, diastolic & MAP were highly different between the control & the patient groups. Regarding fibrinogen level it was lower in the patients with preeclampsia. Platelet count was also reduced in preeclamptic patients. While all platelet indices were higher in the patient group compared to the control group.Conclusion: Platelet indices and fibrinogen level can be used in predicting preeclampsia.

خلفية الموضوع: إن ارتفاع ضغط الدم الشرياني أثناء الحمل (ما قبل الارجاج) هي إحدى الحالات التي تصيب ما بين 6_8% من النساء الحوامل في العالم 0 إن السبب الرئيسي للمرض غير معرف تماما0هناك عده فحوصات مختبريه أجريت في محاوله لتشخيص المرض مبكرا قدر الامكان0حتى قبل إن يرتفع ضغط الدم عند المريضه0أهداف الدراسة:الغرض من الدراسة هو لمعرفه هل إن عوامل الصفيحات الدموية ومستوى الفايبرينوجين يتأثران بشكل واضح بارتفاع ضغط الدم(ما قبل الارجاج)مقارنه بالحمل الطبيعيطريقه الدراسة: دراسة رجعيه أجريت في قسم النسائية والتوليد في مستشفى البتول التعليمي-ديالى-العراق0للفتره من الأول من ايلول2014 إلى الثلاثون من أيلول 2015. تضمنت الدراسة 75 مريضه لها نفس الصفات الديموغرافيه وقد تم تقسيم المريضات إلى مجموعتين:الاولى50 أمراه حامل مصابه بارتفاع ضغط الدم أثناء الحمل والمجموعة الثانيه25 مريضه لا تعاني من المرض إن مده الحمل قدر اعتمادا على الفحص بالأمواج فوق الصوتية(السونار)خلال الأسابيع الأولى للحمل0النتائج:لوحظ إن مستوى الفايبرينوجين كان اقل لدى المريضات اللواتي يعانين من ارتفاع الضغط أثناء الحمل وكذلك عدد الصفيحات الدمويه0بينما عوامل الصفيحات الدموية كانت أعلى لدى المريضات اللواتي لديهن ارتفاع ضغط الدم أثناء الحمل0الاستنتاج:مستوىالفايبرينوجين وعوامل الصفيحات الدموية لها قيمه تنبؤيه في حالات ارتفاع الضغط أثناء الحمل0

Preeclampsia --- Platelet indices --- Fibrinogen levels --- ارتفاع الضغط اثناء الحمل ما قبل الارجاج --- عوامل الصفيحات الدموية --- مستوى الفايبرينوجين