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Article
Evaluation of the haemostatic action of povidone- iodine in dental extraction (Clinical and follow up prospective study)

Author: Ali Q.L. Al-Amiri علي العامري
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2012 Volume: 24 Issue: 2 Pages: 85-87
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: This study aimed to evaluate the haemostatic action of povidone-iodine by irrigation of the alveolarsockets after extraction against the use of normal saline alone.Materials and Methods: This clinical prospective study included 60 patients (35 males, 25 females), ranging in agefrom 20 to 60 years. All minor oral surgery patients at (Oral& Maxillofacial Surgery Department in College of Dentistry/Babylon University) from March 2011 to January 2012. The patients were divided equally into treatment& controlgroups. Povidone-iodine (1%, w/v) was used for irrigation of extraction sockets in the treatment group and saline wasused in the control group.Results: The 60 patients were divided equally into treatment& control groups. Povidone-iodine (1%, w/v) was used forirrigation of extraction sockets in the treatment group and saline was used in the control group. In the treatmentgroup, 24 patients showed cessation of bleeding compared to only 7 in the control group. Povidone-iodinesignificantly (P < 0.01) controlled bleeding as compared to saline.Conclusion: Iodine is corrosive due to its oxidizing potential while povidone is a thickening and granulating agent;together they have a chemocauterizing effect that could be the reason for the cessation of bleeding


Article
Effectivness of 10% povidone iodine as ascolicidal agent in hydatid cyst surgery in compared with other scolicidal agents

Author: Ali Nayyef Assi علي نايف عيسى
Journal: Al-Qadisiyah Medical Journal مجلة القادسية الطبية ISSN: 18170153 Year: 2013 Volume: 9 Issue: 16 Pages: 181-195
Publisher: Al-Qadisiyah University جامعة القادسية

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Abstract

Hydatid disease or Echinococcal disease, is a parasitic disease that affects both humans and other mammals such as sheep, dogs, rodents and horses.[1] There are three different forms of Echinococcosis found in humans, each of which is caused by the larval stages of different species of the tapeworm of genus Echinococcus[1].This study was done in the AL-Husseinteaching hospital (AL-Nassiyria)during3 years (between 1st January 2004 to december2006) and follow up for5 years,120 patients [70 females and 50 males] ages range between 12years to 56years presented withhydatid cyst in the liver only we concentrate on the hydatid cyst of liver( un complicated cases) confirm the diagnosis by U/S and CTscan ,and after surgery follow upalso by U/S and CTscan for 5 years.Povidone-iodine (PVP-I) is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis.[1]To evaluate effectiveness of 10% povidone iodine as ascolicidal agent in liver hydatid cystsurgery in compare with hypertonic salinesolution and alcohol,povidone iodine have a better effect as a scolisidal effect because(1)there'sa lowerrecurrencerate during 5 years post operativlyfollow up (2) there is little post operative complication related to the povidone iodine(3)mild direct effect on the liver cell during six months follow up postoperativelyaccording to the liver function tests results as compare with other scolicidal agents, so we can use povidone iodine10% in surgical operation for hydatid cyst as ascolicidal because it highly effective against the scolices,little intra or post operative effects on the liver cells , cheep and widely available.

دراسه اجريت على 120 مريض خلال 3 سنوات2004 كانون الثاني الى كانون الاول 2006 في مستشفى الحسين التعليمي في الناصريه والمتابعة للمرضى خلال فتره 5 سنوات.هدف الدرسه هو معرفه مدى قوه البوفادين ايودين 10% في قتل طفيليات مرض الاكياس المائية مقارنه بالسائل عالي التركيز (الهايبر تونك) والكحول من خلال حقن كيس الماء الموجود بالكبد ب10 سي سي من البوفادين ايودين 10% او من الهايبر تونك او الكحول لا على التعيين للمرضى اثناء عمليه ازاله الكيس وننتظر لمده 20 دقيقه بعدها تتم عمليه ازاله الكيس بالسحب السوائل وسحب الكيس ثم تتم عمليه المتابعه المتواصله للمريض للتاكد من عوده الاكياس المائية فى الكبد او في الغلاف التجويفي للبطن وكذالك التأكد من مدى تأثيرهذه المواد الثلاثه على خلايا الكبد او وضائف الكبد من خلال فحص وظائف الكبد الدوري لمده ستة شهور.تبين من خلال دراستنا بان مفعول البوفادين ايودين فعال جدا في قتل طفيليات الاكياس المائيةمقارنه بالمادتين الاخريين وله تاثيرات جانبيه قليله على الكبد ووضائفه وله اق نسبه على عوده الاكياس المائيه بالنسبه الى المادتين الاخريتين,لذا ننصح باستخدام البوفادين ايودين 10% كمحلول قاتل لطفيليات الاكياس المائيه اثناء عمليه رفع الاكياس ولأنه ايضا رخيص ومتوفر


Article
Antibacterial efficacy of surgical scrubbing solutions

Author: Bassam F. Izalddin
Journal: Muthanna Medical Journal مجلة المثنى الطبية ISSN: 2226146x Year: 2018 Volume: 5 Issue: 1 Pages: 21-34
Publisher: Al-Muthanna University جامعة المثنى

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Abstract

Surgical scrubbing with antibacterial solutions is an important step in surgical operations to reduce the incidence of surgical site infection. The aim of study is to evaluated superiority of one of three surgical scrubbing solutions commonly used (povidone iodine, chlorhexidine and aqueous alcohol) by studying their antibacterial action on the skin of the hands of the operating personale. Ninety hands of surgeons, assistants and nurses were included in this study at Al Kindy Teaching Hospital from 1 June, 2011 to 1 Feb, 2012. Divided into three groups each with 30 hands according to the antiseptic solution used for scrubbing (chlorhexidine ( group 1); povidone iodine (group 2) and ethanol alcohol (group 3), hand prints were cultured as a baseline, immediately and 30 minutes after scrubbing for both gram +ve and gram –ve bacteria and a total of 540 culture medias were studied. In our study Staphylococcus aureus was the only gram positive transient bacteria found in the culture medias with a baseline ranged (0-5) colonies in group 1, (0-5) colonies in group 2 and (0-7) colonies in group 3 and all were removed immediately after scrubbing with all antiseptic solutions. Staphylococcus epidermidis was the only residents bacteria found in all the hands with a baseline ranged (10-60) colonies in group 1, (12-62) colonies in group 2 and (10-56) colonies in group 3. This bacterium was reduced to low levels immediately after scrubbing with all antiseptic solutions and completely removed after 30 min in group 2, 3 and reduced to lowest level in group 1. Gram –ve bacteria was not found in the entire three groups. In addition to that, fungi were found in all our study groups in a range of (0-7) colonies in groups 1, (0-8) colonies in group 2 and (0-8) colonies in group 3 and all of them were removed by scrubbing with all antiseptic solutions. We concluded that Povidone iodine was more effective in eradicating or reducing of both gram +ve resident and transient bacteria and fungi.


Article
Povidone Iodine and Hypertonic Saline Induced Sclerosing Cholangitis in Hepatic Hydatid Cysts Surgery

Author: Abdulrazzak Kalaf Hassan
Journal: Karbala Journal of Medicine مجلة كربلاء الطبية ISSN: 19905483 Year: 2017 Volume: 10 Issue: 2 Pages: 2680-2686
Publisher: Kerbala University جامعة كربلاء

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Abstract

background: Surgery is the treatment of choice for hepatic hydatid disease but surgical treatment carry the risk of recurrence if we do not use a proper scolicidal agent and may convert patient with solitary hepatic hydatid cyst to patient with many incurable cysts. The ideal scolicidal agent should kill vital scolices, and not have local or systemic adverse effect, and not toxic to bile duct. Yet, there is no ideal scolicidal agent involving such effects. One of the important serious complications after instillation of scolicidal agents is sclerosing cholangitis.Aim: to assess the risk and severity of povidone iodine and hypertonic saline induced sclerosing cholangitis in guinea pigs.Materials and methods: In this study we used twenty guinea pigs which were divided into two equal groups. In the first group 0.3 ml10% povidone iodine was injected to the biliary tree after clamping then released after five minutes and second group, 0.3 ml 20% hypertonic saline was used.Four months later on the pig was euthanized by ether and three biopsies taken from the liver and sent for histopathological examination. Afterwards, the liver, gall bladder, the common bile duct and the duodenum were excised in one piece and immediately transferred for cholangiography. Two X-ray films were taken for each specimen in lateral and antero-posterior view after contrast material injection. Results: in povidone iodine group 8 animals (80%) had sclerosing cholangitis while in hypertonic saline group only 2 animals (20%) had sclerosing cholangitis. This difference between the two groups was statistically significant. Conclusions: Usage of 10% povidone iodine as a protoscolicidal agent carry high risk of sclerosing cholangitis.


Article
.The effectiveness of irrigation method by normal saline compared to povidone iodine soaking in decreasing the rate of contamination in appendectomy wound
دراسة فعالية الغسل بالنورمال سلاين اوالانقاع باليود وتاثيرها في تقليل نسبة التهاب جروح عمليات الزائدة الدودية

Authors: Hassan A. Hassan --- Mohannad K.Al-Bermani مهند كامل البيروني --- Aws B. Abed* اوس بشير عبد
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 / 24108057 Year: 2016 Volume: 58 Issue: 3 Pages: 233--237
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: The number of bacteria is important as much as the type of it in developing wound infection. Pressurized irrigation of the surgical wound leads to decrease bacterial number which led to decrease incidence of wound infection.Objective: to evaluate effectiveness of normal saline irrigation and povidone iodine soaking in decreasing the number of bacteria.Patient and method: This was a prospective study of 100 patients who were admitted to Al Kadhimyia Teaching Hospital during the period from May 2012 and April 2013 with diagnosis of acute appendicitis. After appendicectomy was done, patients were randomized into two groups, fifty patients (group one) the subcutaneous tissue was irrigated by 200 ml normal saline. The subcutaneous tissue of the other fifty patients (group two) was soaked by 10 percent povidone iodine solution. Swabs were taken from subcutaneous tissue before and after irrigation or soaking in both groups. All swabs were implanted in special type of agars. The number of colonies appeared represents the number of bacteria that grow under the incubation conditions employed.Results: there was a significant reduction in the number of bacterial colonies in group I; compared to group II.Conclusion: Irrigation of the subcutaneous tissue with normal saline is an effective method in decreasing the rate of bacterial contamination when compared to the use of povidone iodine soaking.Keywords: Normal saline, povidone iodine, irrigation, wound infection, contamination, bacteria.

الخلفية:ان وجود الخلايا البكتيرية يؤدي الى حدوث التهابات في الجروح ,ولذا فان غسل الجروح وازالة تلك الخلايا البكتيرية يؤدي الى تقليل نسبة الاصابة بالتهابات الجرح بعد العمليات الجراحية الغرض: تقييم فعالية الغسل بالنورمال سالاين و الانقاع بمحلول اليود لتقليل نسبة التلوث في الجروح.المرضى والطريقة: أجريت هذه الدراسة المستقبلية في الفتره ما بين ايار2012 الى نيسان 2013 في مستشفى الكاظمية التعليمي في بغداد و ضمت 100مريضا ادخلوا الى المستشفى و هم يشكون من اعراض التهاب الزائدة الدودية الحاد حيث اجريت لهم عملية رفع الزائدة الدودية تحت التخدير العام.وقبل خياطة جرح العملية, تم غسل الجرح لخمسين مريضا منهم (المجموعة 1) باستخدام200 مل من محلول النورمال سالاين بالحقن بواسطة السرنجة, وانقاع جرح خمسين اخرين (المجموعة 2) بمحلول اليود10% . اخذت مسحتين قبل و بعد عمليتي الغسل و الانقاع لكل مريض,ثم زرعت المسحات الماخوذة في اوساط زرعية خاصة و حظنت لمدة 48 ساعة بدرجة حرارة 37 مئوية. تم حساب عدد المستعمرات البكتيرية حيث ان عددها يمثل عدد الخلايا البكتيرية المنفردة التي تم زرعها و التي تمثل بالتالي نسبة التلوث في جرح العملية.النتائج: بينت النتائج ان هناك انخفاظا ملحوظا في عدد المستعمرات البكتيرية بعد عملية الغسل بالنورمال سالاين. كمااظهرت النتائج انخفاظا طفيفا في عدد المستعمرات البكتيرية بعد عملية الانقاع بمحلول اليود 10%.الاستنتاج: ان النتائج المستحصلة من هذه الدراسة تشير الى فعالية الغسل بالنورمال سالاين في تقليل نسبة التلوث البكتيري في جروح عمليات الزائدة الدودية اذا ما قورنت بفعالية الانقاع بمحلول اليود 10%. مفتاح الكلمات :محلول النورمال سلاين , محلول اليود, الغسل, التهاب الجرح , التلوث , البكتيريا

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