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Article
Socio-demographic and clinical characteristics of psoriatic patients attended dermatology clinics in Mosul city

Authors: Bassam Abd Al-Mobdi Al-Neema بسام عبد المبدي النعمة --- Salah Ali Al-Ashow صلاح علي العشو
Journal: Annals of the College of Medicine Mosul مجلة طب الموصل ISSN: 00271446 23096217 Year: 2012 Volume: 38 Issue: 2 Pages: 23-27
Publisher: Mosul University جامعة الموصل

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Abstract

ABSTRACTBackground: Psoriasis affects 0.5-0.7% of Iraqi people making it one of the significant dermatological problems. Despite the extent of this problem, little information regarding its epidemiology is available in this country. Objectives: To define the socio-demographic and clinical characteristics of psoriatic patients attended dermatology clinics in the four major governmental hospitals in Mosul city.Patients and methods:Study setting: Dermatology clinics in the 4 major governmental hospitals (Al- Jamhouri, Ibn Sina, Al-Salam, and Al- Mosul) in Mosul.Study design: Cross-sectional study.Study period: 1st October 2101 to 25th of February 2011.Participants: Patients with psoriasis of both sexes, and all ages, who attended the dermatological clinics. Each patient was subjected to detailed history and clinical examination. Data collection form included various demographic and clinical characteristics.Results: The sample of the study included 154 patients with psoriasis, comprising 50.6% males ranging in age from 3-62 years. The mean age±SD at presentation was 30.2±15.1 years; the mean age±SD at onset was 22.8±12.0 years. The mean duration of the illness was 7.4 years. A unimodal distribution curve of age at onset was noticed with a peak at the third decade. Early onset of psoriasis before 30 years was significantly associated with family history. Severity of psoriasis was mild in 74 (48.1%) of cases and it was more severe in elderly with longstanding disease. Itching and disfigurement were the main complaints especially the young and female patients. Plaque type (64.9%) was the most common variant, arms (52.6%) were the most commonly affected body site, and the scalp (27.9%) was the most common initial site affected by psoriasis. Nail involvement was seen in 30 (19.5%) patients especially fingernails. Conclusions and recommendation: The study revealed that psoriasis is a heterogeneous disease affecting all ages, genders and socio-economic strata. Further researches to study the relationship and the impact of these characteristics on the life of sufferers is recommended.

الخلاصةالخلفية: يصيب داء الصداف 0.5-0.7% من السكان في العراق مما يجعل هذا المرض من المشاكل الجلدية الرئيسية. وبالرغم من ذلك يتوفر القليل من البيانات الخاصة بوبائية هذا المرض في هذا البلد.الأهداف: تحديد الصفات الاجتماعية والديموغرافية والسريرية لمرضى داء الصداف المراجعين لمستشفيات الموصل الأربعة الكبرى.طرق البحث:موقع الدراسة: عيادات الأمراض الجلدية في المستشفيات الأربعة الرئيسية (الجمهوري، ابن سينا، السلام والموصل) في مدينة الموصل.مدة الدراسة: للفترة من1-10-2010 ولغاية 25-2-2011.تصميم الدراسة: طريقة الدراسة المقطعية.المشاركون في الدراسة: ضم البحث مرضى داء الصداف الذين راجعوا عيادات الأمراض الجلدية من كلا الجنسين وبكل الأعمار. أجري البحث بطريقة المقابلة المباشرة والفحص السريري تم من خلالها جمع المعلومات الاجتماعية والديموغرافية والفحص ألسريري للمريض.النتائج: أجري البحث على 154 مريضا مصابا بداء الصداف شكل الذكور نسبة 50.6% وقد تراوحت أعمارهم بين 3-62 عاما وبمتوسط عمر قدره 30.2±15.1 سنة. وكان متوسط عمر بداية ظهور داء الصداف هو 22.8±12 سنة ومتوسط مدة المرض هي 7.4 عاما. أظهرت النتائج أن توزيع عمر بداية ظهور داء الصداف هو أحادي القمة عند العقد الثالث من العمر. وقد ارتبط العمر المبكر للمرض بالتاريخ العائلي للمرض خصوصا. وكانت شدة داء الصداف خفيفة لدى 74 (48.1%) مريضا. ولوحظ زيادة في شدة المرض مع زيادة عمر المريض أو مدة المرض. وكان الحك والتشوه الجلدي المعاناة الأكثر شيوعا بين المرضى خصوصا الشباب والنساء. وكان النوع ألصفيحي أكثر أنواع داء الصداف شيوعا (64.9%) والأطراف العليا الأكثر إصابة (52.6%) وفروة ألرأس أول المناطق إصابة عند بداية ظهور المرض (27.9%) وقد عانى 30 (19.5%) مريضا من حالة صداف الأظافر متزامنا مع داء الصداف الجلدي خصوصا أظافر أصابع الكفين.الاستنتاج والتوصيات: أظهرت الدراسة شدة تباين مرض داء الصداف وان كلا الجنسين وكافة الفئات العمرية والاجتماعية معرضة للإصابة بهذا المرض ويوصى بأجراء المزيد من البحوث لدراسة العلاقة بين هذه الصفات وتأثيرها على حياة المصابين.


Article
Efficacy and Safety of Topical Podophyllin 5% Ointment in Patients with Mild Plaque-Type Psoriasis

Authors: Khalifa E.Sharquie --- Adil A.Noaimi --- Wesal K. Al-Janabi*
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2013 Volume: 12 Issue: 2 Pages: 251-258
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT: BACKGROUND: Psoriasis is a common chronic condition of the skin that is resistant to many therapies. There is a need for the development of novel non-steroidal topical drugs for the treatment of psoriasis.OBJECTIVE: To assess the efficacy and safety of topical podophyllin 5% ointment in patients with mild plaque-type psoriasis.PATIENTS AND METHODS: Sixty two patients with mild plaque-type psoriasis were enrolled in this study. They were dividedinto 3 groups: GroupA (21patients)were treated with podophyllin 5% ointment every other day,while Group B(20patients)were treated with clobetasol propionate 0.05%ointment twice daily and21 patients in Group C were treated with Vaseline twice daily for 8 weeks as a control group.Efficacy was evaluated every 2 weeks for 8weeks using Psoriasis Area and Severity Index (PASI)score and relapse was recorded after cessation of treatment in those patients who achieved goodresponse during 8 weeks follow up period.RESULTS: A total of 62patients were 44(70.9%) males and 18(29.0%) females, with: male: female ratio 2.3:1.Their ages ranged from 18-65 (37.5±12.9) years. Their baseline PASI score ranged from 1.29(5.2±2.4).Attheendof8weeksoftherapy:nostatisticallysignificantdifferenceinPASIreductionbetweenGroupA(66.3±20.7) and Group B(68.1±34.2) treated patients, P-value =0.831 and both of themwere statistically significant higher PASI reduction than patients with Group C,34.1±28.8, P-value=<0.001.Regarding the percentage of patients who achieved good response, there was nostatistically significant difference between Group Aand Group B, 95.3% versus 70% ( Pvalue=0.083)and both of them achieved a statistically significant higher percentage of patientswith good response than Group C,47.6%, P-value=<0.001. Although the percentage of patientswith complete clearance (PASI≥90%) in the Group Awas much less, 9.5%, than that of Group B,65% (statistically significant, P-value=< 0.001), the total relapse rate during 8 weeks follow up wasmuch lower among Group Apatients, 25% versus 70%, P-value=0.043.On the other hand nocomplete clearance was achieved in the Group Cand their relapse rate was 80%.Regarding side effects: Group A, 9.5% of patients developed hypopigmentation, Group B, 10% ofpatients developed pyoderma and Group C, no side effects were reported. There was no statisticallysignificant difference among the three groups regarding the frequency of side effects (P = 0.355).CONCLUSION: Podophyllin 5% ointment on every other day regimen was as effective as clobetasole 0.05%ointment twice daily at the end of 8 weeks treatment with no side effects and with a much lowerrelapse rate.


Article
قياس مستويات الانترفيرون كاما , الانترليوكين 17 والانترليوكين 4 في مصل مرضى داء الصدفية في مدينة النجف

Authors: Ebtihal Ch. Abbas --- Ali M. Almuhana --- Muhsin A. Al- Dhalimi
Journal: kufa Journal for Nursing sciences مجلة الكوفة لعلوم التمريض ISSN: 22234055 Year: 2013 Volume: 3 Issue: 3 Pages: 102-108
Publisher: University of Kufa جامعة الكوفة

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Abstract

Background: Psoriasis is an inflammatory skin disorder characterized by activation of lymphocytes, systemic and local over expression of pro-inflammatory cytokines. Objectives:- The study was designed to investigate the level of cytokines in patients with psoriasis and study the correlation of the cytokines with disease severity.Patients and Methods: Blood samples were collected from seventy patients with psoriasis for measurement of (IFNγ, IL-17 and IL-4) by ELISA technique.Results: High levels of IFNγ and IL-17 were observed in patients with psoriasis. It was found that the mean levels of IFNγ and IL-17 were significantly correlated to disease severity. Moreover, the mean level of IL-4 in psoriatic patient was found to decrease significantly according to graded severity of the disease. Statistical analysis was done by using SPSS (statistical package for social sciences) in which T-test and ANOVA test were used and chi- square (X2) test for categorical data.Conclusion: The study concluded that the level of IFNγ and IL-17 may play a key role as an indicator in the immunopathogenesis of psoriasis and markers of disease activity.Recommendation:-Using another cytokines and study effect of these cytokines with disease severity.

الخلفية :- الصدفية هو مرض جلدي التهابي يتميز بتفعيل الخلايا اللمفية وزيادة انتاج الحركيات الخلوية على المستوى الموقعي والجهازي للجسم.الاهداف:- صممت هذه الدراسة لفحص مستوى ا الحركيات الخلوية لدى المرضى المصابين بداء الصدفية ودراسة الارتباط بين هذه الحركيات الخلوية ومدى شدة المرض. المرضى وطرق العمل:- اخذت عينات دم من سبعين مريض لقياس مستوى الحركيات الخلوية ( IFNγ, IL-17و IL-4) بتقنية الايلايزا. النتائج:- ينت الدراسة ارتفاع مستوى ( IFNγوIL-17) لدى مرضى الصدفية, وتبين ان هناك فرق معنوي في معدل مستويات (IFNγ, IL-17 ) عند المصابين مقارنة مع مستوياتهما عند مجاميع السيطرة وهناك علاقة ملحوظة بين ارتفاع مستوى هذه الحركيات الخلوية وشدة المرض. كذلك وجد ان مستوى (IL-4) لدى المرضى المصابين بالصدفية يقل معنويا بشكل ملحوظ بالنسبة لشدة المرض. تم استخدام نظام SPSS لتطبيق اختبار T و اختبار الانوفا واختبار الفرق المعنويالاستنتاج:- يمكن الاستنتاج في هذه الدراسة ان مستوى الحركيات الخلوية (IFNγ and IL-17) ربما لها دور كدليل في الامراضية المناعية لداء الصدفية وتعتبر كمعلمات لدرجة فعالية المرض. التوصيات:- استخدام حركيات خلوية اخرى و دلراسة تاثيرها على شدة داء الصدفية


Article
Black Cumin Oil: A New Treatment for Palmoplantar Psoriasis

Author: Naseer A. Al-Harchan نصير عبد الامير
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2010 Volume: 52 Issue: 2 Pages: 205-208
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Palmoplantar psoriasis is a therapeutically challenging condition that can significantly impact patient quality of life as it directly affects activities. However, despite this impact, few clinical studies address treatment. Herbs and their extracts have been used for treatment of skin disease for centuries. One of the most popular herbs in our society is black cumin or seed of blessing oil (Nigella Sativa); this plant had diverse clinically useful activity.Patients and Methods: This study was conducted in the Department of Dermatology and Venereology in Baghdad Teaching Hospital, Iraq during the period between January and October 2003. In this single-blind randomly controlled therapeutic study, thirty patients were enrolled, their ages ranged from 22-65 years. There were 18` females and 12 males. The patients were divided into 2 groups; group A (20 patient) instructed to use nigella sativa 10% ointment twice daily for 3 months, while group B (10 patient) used a control ointment(Vaseline) . Statistical analyses were carried out by computer using t-test, and chi-square when needed. Results: twenty-four patients completed the study. In group A (18 patients), we noted a significantly reduction of the thickness and fissuring of the skin of the affected part which was also become very soft after 3 months of therapy. The response of patients to treatment was good in 50%, moderate in 27.8% and mild response in 22.2%. The satisfaction of patients with treatment was full in 61.1%, partial in 27.8%, and no satisfaction in 11.1%. In group B (6 patients), the lesions showed no significant reduction after 3 months and the response of patients to treatment was good in 16.6%, moderate in 33.4%, and mild response in 50%. The satisfaction of patients with treatment in this group was full in 16.6%, partial in 50%, and no satisfaction in 33.4%. The difference in outcome after 12 weeks between the 2 study groups was statistically significant.Conclusion: The ointment of the black cumin is considered as a very good remedy for the palmoplantar psoriasis. This remedy is considered to be very safe, cheap and easy to prepare with no serious side effects as compared to the previous ointments for this type of psoriasis.Key words: Black Cumin, Palmoplantar Psoriasis


Article
Estimation the concentration of IL- 23, and IL-17A in the sera of patients with psoriasis in Baghdad city
تقدير تركيز الانترليوكين-23 والانترليوكين-17أ في مصول مرضى الصدفية في مدينة بغداد

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Abstract: Psoriasis is a common, chronic, disfiguring, inflammatory, hyperproliferation, and abnormal differentiation of keratinocyte, in which both genetic and environmental influences have a critical role. The study was designed to detection the levels of IL-23 and IL-17A among psoriatic patients compared with healthy group, also studied the correlation between them and some parameter such as:-age of onset and severity of psoriatic patients. Fifty psoriatic patients were selected randomly from both sexes with ages from (10-70) years. Patients were diagnosed clinically by dermatologist. Sera samples of both groups were collected from all individuals for the estimation levels of IL-23 and IL-17A by ELISA technique. All mean values sera levels (IL-23 96.74 pg/mL and 6.56 pg/mL for IL-17A ) of patients were significantly higher than those of controls (18.74 and 3.01 pg/mL for IL-23and IL-17A respectively). There was a high significant in levels of patients sera of IL-23 and IL-17A, in compared with healthy control group according to these normal values. Furthermore, there was a significant correlation between the levels of IL-23, and age of disease onset among psoriatic patients. In contrast there was no significant association between the severity & interleukins (Il-23 and Il-17A). Emerging data in humans reveals a critical contribution of IL-23 and IL-17A in the pathogenesis of psoriasis. The IL-23 and IL-17A pathways were atherapeutic targets for biologic agents and systemic therapies in psoriasis treatment

الخلاصة:الصدفية مرض جلدي شائع مزمن والتهابي يزداد فيه التكاثر والتمايز غير الطبيعي للخلايا المتقرنه التي يؤثر فيها العوامل الوراثية والبيئية على حد سواء بدور حاسم. صممت هذه الدراسه لكشف مستوى الانترلوكين23 والنترلوكين17أ بين مرضى الصدفية ومقارنتهم بمجموعة الاصحاء وكذالك دراسة الارتباط بينهم وبعض المتغيرات مثل عمر بداية ظهور المرض وشدة المرض لدى مرضى الصدفية. ضمت الدراسة خمسين مريضا بداء الصدفية تم اختيارهم بشكل عشوائي لكلا الجنسين وكانت اعمارهم تتراوح من (10-70) سنة. شخص المرضى سريريا بواسطة اخصائي الجلدية. وقد تم جمع العينات المصلية لكلتا المجموعتين ولكل الافراد وذلك لتقدير مستويات الانترلوكين 23 والانترلوكين 17أ بتقنية اليزا. اظهرت نتائج الدراسة اختلافات معنوية عالية في متوسطات المستويات المصلية لكل من انترلوكين 23 (74و96 بيكوغرام/مل) وانترلوكين 17أ (56و6 بيكوغرام/مل) لدى جميع مرضى الصدفية مقارنة بالاصحاء (74و18 و 01 و3 بيكوغرام/مل) للانترلوكين 23و17أ على التوالي. كمااظهرت الدراسة وجود فروقات معنوية عالية في مستويات مصول المرضى للانترلوكينات 23 و17أ عند مقارنتها بمجموعة الاصحاء بحسب مستوياتها الطبيعية. ومن ناحية اخرى هناك ترابط معنوي بين مستويات الانترلوكين 23 وعمر بداية ظهور المرض لدى مرضى الصدفية . وهناك نتيجة مغايره بعدم وجود ارتباط معنوي بين شدة المرض ومستويات الانترلوكينات (23 و17أ). الحقائق المنبثقه من الانسان كشفت مساهمة حاسمة للانترلوكينات 23 و17أ في امراضية داء الصدفية وان الانترلوكينات( 23 و17أ) لها مسارات في الاهداف العلاجية فيما يتعلق بالعوامل الحيوية والعلاجات الجهازية في معالجة داء الصدفية.

Keywords

Psoriasis --- IL-23 --- IL17A


Article
Evaluation of Lipid Profile in Psoriatic Patients Treated by Methotrexate And Retinoid
تقييم مستوى الدهون لمرضى الصدفية الذي عولوجوا بادوية الميثوتريكسات والريتينويد

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Abstract

Background: Psoriasis is a common disease with the population prevalence ranging from 2%to 3%. Its prevalence in the population is affected by genetic, environmental. Psoriasis isassociated with an atherogenic lipid profile but longitudinal changes in lipids around diseaseonset are unknown. Because of the wide range of comorbid conditions associated withpsoriasis, comprehensive screening and treatment must be implemented to most effectivelymanage psoriasis patients. The aim of this study is to examine the effect of type of treatment(methotrexate & retinoid) on serum lipid profiles for psoriatic patients. Methods: Comparedthe changes in lipid profiles in a psoriatic 50 patient , 20 of them as a control group never takea treatment, 15 psoriatic patient treated by methotrexate, and 15 psoriatic patient treated byretinoid. All lipid measures index data were abstracted. Random-effects models adjusting forage, sex and calendar year were used to examine trends in lipid profiles. Result: Decreaseserum total cholesterol, low density lipoprotein, and high density lipoprotein in psoriaticpatient on methotrexate, while increase triglyceride level with systemic retinoid. Conclusions:Psoriatic patients could be considered as a group with an increased atherosclerotic risk becauseof susceptibility in lipid profile.

Keywords

Psoriasis --- MTX --- Retinoid


Article
Childhood psoriasis a clinical and epidemiological study in Samawa city

Author: Arwaa A. abdul-hussein
Journal: Muthanna Medical Journal مجلة المثنى الطبية ISSN: 2226146x Year: 2019 Volume: 6 Issue: 2 Pages: 29-34
Publisher: Al-Muthanna University جامعة المثنى

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Childhood psoriasis is common, but it has not been adequately reported in our city. This study was done to evaluate the epidemiological and clinical findings in children with psoriasis and to compare the data with those from other studies. Thirty children with psoriasis were taken in this study which is done in outpatients’ dermatological clinic during the period from July of 2018 to December of 2018. The age of our patients ranged from 6 months to 14 years, in which there are17 boys and 13 girls. The Plaque type psoriasis and generalized distribution were the commonest findings. Positive family in (36.6%), kernelization was (30%). The frequent symptom was pruritus (16.6%) and discomfort 10%. As a result, childhood psoriasis is a different entity from adult psoriasis, early diagnosis, and appropriate management are particularly important in children to solve long-term disease-related psychosocial problems.

Keywords

Psoriasis --- Vulgaris --- Guttate --- Childhood


Article
Neovascularization in Psoriatic Patients

Authors: Zina Hammad Mohammed --- Yesar Mohammed AL-Shamma --- Hadi Abed Hadi Al-Wakeel
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2015 Volume: 12 Issue: 3 Pages: 638-645
Publisher: Babylon University جامعة بابل

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Abstract

Although angiogenesis may not be the main event in the pathogenesis of psoriasis, identifyingthe pathways leading to angio-proliferation mayaid in discovery of novel antipsoriatic drugs. Vascular endothelial growth factor is a principal regulator of physiological and pathologicalneoangiogenesis.The aim of the study is to assess the serum level of vascular endothelial growth factor in psoriatic patients and its correlation with Psoriasis area and severity index score (PASI score). One hundred consentingpsoriatic patients(males and females)aged 20-60 years who attended different medical centers including Al-Sadr Medical City and department of laser research in AL-Najaf city and Marjan Medical City in AL-Hilla-Iraq.Psoriasis area and severity index assessment was done for each patient. Blood samples were collected for vascular endothelial growth factor measurement.The serum level of vascular endothelial growth factor was significantly increased in all groups of,psoriatic,patients comparedto healthy controls as well as serum vascular endothelial growth factor showed positive correlation with PASI score.


Article
Serum zinc in psoriatic patients

Author: Adnan Abd Oun Hashim Al-Jebory
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2012 Volume: 11 Issue: 2 Pages: 20-23
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Background: Psoriasis is a common skin disorder affecting 1% to 3% of thepopulation all over the world. Many etiological factors have beenimplicated but trace elements, especially zinc, may play an importantrole.Aims: This study was done to evaluate the serum level of zinc in patientswith psoriasis and it's relation to clinical types, duration and surface areaof the disease.Patients and Methods: Fifty patients (25 males & 25 females) withdifferent ages and different types of psoriasis were chosen for thisstudy. Also 50 non-psoriatic volunteers, sex and age matched wereserved as controls, evaluated for serum zinc level.Results: The result of this study has shown that 49 (98%) of psoriaticpatients have low serum zinc compared with 2 (4 %) among controls(P=0.0001). The type of psoriasis may have an effect on serum zinc, thelowest mean serum zinc is found in palmo-planter (plaque) psoriasis (14%of patients) (P=0.025).Conclusions: From this study we can conclude that zinc deficiency mayplay a role in psoriasis since most patients (98%) have low serum level.


Article
Incidence and Antibiotics Resistance of Staphylococcus aureus isolated from Skin Lesion of Psoriasis Patients
مدى مقاومة المضادات الحيوية للمكورات العنقودية الذهبية المعزولة من منطقة الجلد المصاب للمرضى المصابين بداء الصدفية

Author: Ebtihal Chiad Abbas ابتهال جياد عباس
Journal: journal of al-qadisiyah for pure science(quarterly) مجلة القادسية للعلوم الصرفة (فصلية). ISSN: 19972490 Year: 2014 Volume: 19 Issue: 2 Pages: 84-71
Publisher: Al-Qadisiyah University جامعة القادسية

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Abstract

Isolation of Staphylococcus aureus was ought to be the reduced local defensefactors in the lesion due to local and systemic immunosuppressant drugs likecytotoxic drugs and corticosteroid used for the treatment of psoriasis. The study aimto investigate the incidence and antibiotic resistance ability of these bacteriaassociated with psoriasis. Skin swab was taken from lesional skin of psoriasispatients for isolating of S. aureus. Isolates identified by conventional tests andconfirmed with 16SrRNA specific primers. Among all patients, 37(52.9%) isolateswere identified as S. aureus. All isolates tested for methicillin susceptibility using aninitial screening test. The results showed 34(91.9%) isolates that resisted to pencillin,29(78.4%) isolates resisted to methicillin and 22(59.5%) isolates that resisted tooxacillin. All isolates showed sensetivity to vancomycin and linezolid and thenconfirmed by used genotypic detection for presence of mecA gene. From this isolates,mecA gene was detected in 14 isolates. There were differences in resistance toantibiotics observed between mecA-positive and mecA-negative isolates

ان عزل بكتريا المكورات العنقودية الذهبية من المرضى المصابين بداء الصدفية يعود الى اختزال عوامل الدفاع الموقعية في منطقة الاصابة نتيجة العقاقير المثبطة مناعيا مثل العقاقير السامة للخلايا والستيرويدات التي تستخدم لعلاج الصدفية . تهدف هذه الدراسة لفحص مدى قابلية المقاومة للمضادات الحيويةلبكنريا المكورات العنقودية الذهبية المقترنة بداء الصدفية. لقد تم اخذ مسحات جلدية من منطقة الاصابة لمرضى الصدفية لعزل البكتريا العنقودية الذهبية. حددت العزلات بواسطة الاختبارات التقليدية وعززت بالطرق الجزيئية باستخدام البادىء 16SrRNA المتخصص .بينت النتائج ان من بين كل المرضى هناك 37 )9و52%( عزلة حددت بانها مكورات عنقودية ذهبية. اختبرت جميع العزلات لحساسيتها للمثسلين باستعمال اختبار الحص البدائيوقد تبين ان هناك 34 )%9.91( عزلة مقاومة للبنسلين و 29)%4.78( عزلة مقاومة للمثسلين و 22)5.59%( عزلة مقاومة للاوكساسلين.اظهر جميع العزلات حساسيتها لكل من الفنكومايسين واللينوزوليد. ثم عززت هذه النتائج بتحديد الجينوتايب لوجود جين mecA وقد اظهرت الدراسة 14 عزلة حاملة لهذا الجين وقد لوحظ ان هناك فرق لمقاومة المضادات الحيوية بين العزلات الحاملة لهذا الجين والعزلات الفاقدة له. توصلت هذه الدراسة الى الاستنتاج بان بكتريا المكورات العنقودية المعزولة من منطقة الجد المصابة لمرضى داء الصدفية لها علاقة بالمرض وهناك ارتباط معنوي بين مقاومة هذه البكتريا التي تمتلك mecA جين وبين داء الصدفية . حيث تبين ان لهذه البكتريا دور في زيادة حدة هذا المرض عند امتلاكها للmecA جين

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