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Article
Results of Kidney Biopsies among Adult Iraqi Patients in a Single Center

Authors: Nawar S.Jameel نوار جميل --- Mohammad Abdul Mahdi محمد عبد المهدي --- Ali Jasim H. Al-Saedi علي جاسم الساعدي
Journal: Al-Kindy College Medical Journal مجلة كلية الطب الكندي ISSN: 18109543 Year: 2011 Volume: 7 Issue: 1 Pages: 82-84
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Patients requiring renal biopsies have various glomerular diseases according to their demographic characteristics.Objective: To study types of glomerular disease among adult Iraqi patients in a single center in Baghdad/IraqMaterial and Methods: A total of 120 native kidney biopsies were studied. All biopsies were adequate and were processed for Light Microscopy.The age range of the study patients was 17-67 years, with a mean of 38.5 years. The mean follow up period was 28 weeks (4-52 weeks)Indication for biopsy included: Nephrotic syndrome (N=72; 60%), Asymptomatic proteinuria (N=21; 17.5%), acute nephritic presentation (N=17; 14.16%), asymptomatic haematuria (N=10; 8.33%).Results: Primary glomerulonephritis (GN) was seen in 102 of 120 patients (85%), focal segmental glomerulosclerosis, and membranous nephropathy were the most common histological diagnosis (33.3% and 21.5% respectively).Conclusion: The study further emphasize the need for national GN registry and long term follow up, to recognize the common pattern of GN, their natural history, the appropriate line of management, and to try to halt their progression to end stage renal disease (ESRD).Key Words: Iraq, Glomerulonephritis, Renal Biopsy.


Article
Pediatric Glomerular Diseases (Review of histopathological subtypes)

Authors: Nariman F.A. Azat نرمان فهمي --- Numan N. hameed نعمان نافع --- Onss A. Sahib انس احمد
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2010 Volume: 52 Issue: 1 Pages: 1-3
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Glomerular injury can be caused by immunologic, infectious, toxic, metabolic and heamodynamic factors. The glomerular response to injury determines the pathology, which can be observed in renal biopsy. The purpose of this study was to analyze different histopathological subtypes of primary and secondary glomerular diseases in children.Patients and methods: A retrospective study was done on 100 renal biopsy cases in children welfare teaching hospital between December 2003 and December 2007. Ultrasonically guided biopsies were taken and only light microscopy was used to examine the specimens.Results: The study group included 100 cases with renal diseases, 83 (83%) cases of which having primary glomerular disease, the remainder 17 (17%) cases represented secondary glomerular disease. The patients age ranged between (1month-15 years).The frequency of the different entities of primary glomerular disease was: focal segmental glomerulosclerosis (FSGS %) 27 (27%), Minimal change disease22 (22%), Mesangioproliferative glomerulonephritis21 (21%), Mesangiocapillary Glomerulonephritis7(7%) and congenital nephrotic syndrome 6 (6%).patients with secondary glomerular diseases: 14 (14%) patients had Systemic Lupus Erythromatosis(SLE), 2(2%) Henoch-Schonlein Purpura and 1(1%) Amyloidosis . Conclusion: The results of this study were comparable to other studies, with Focal segmental glomerulonephritis being the most common primary glomerular diseases and systemic lupus erythromatosis being the most common secondary glomerular diseases in children. Further study on a much larger scale with the utilization of immunoflourescent and electron microscopy with full serology and infectious screening is needed to provide deeper understanding of these different diseases. Keywords: Glomerular diseases, renal biopsy, Children


Article
RENAL BIOPSY PRACTICE IN IRAQ: A SYSTEMATIC REVIEW

Authors: Ala Sh. Ali علاء الشيخ علي --- Ali J. Al-Saedi علي جاسم الساعدي
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2016 Volume: 14 Issue: 4 Pages: 393-399
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Background:Renal biopsy is an indispensable tool for the accurate diagnosis and treatment of different forms of renal disease. Many advances have improved the utility and safety of renal biopsy procedure.Objective:To determine the extent to which renal biopsy used and how much it affects the Iraqi nephrology practice.Methods:A systematic review of articles published from 1990 to 2014 was carried out by searching Medline and Google scholar. We included all studies that concerned with renal biopsy as the main intervention. Eligible studies determined by predefined criteria were reviewed. Data from these studies combined and analyzed. Results:The search yielded 55 title, of which, eleven studies met the inclusion criteria. Analysis of the 11 studies (2278 patients) that underwent 2667 renal biopsies. Ten studies centered on native renal pathology and one study focused on allograft pathology.Conclusion:The Iraqi renal biopsy practice and pathology interpretation need to be rejuvenated by modern pathology services, data registry, and well-designed studies with clinical impact.Keywords:Renal biopsy, Allograft, Pathology, Iraq.

Keywords

Renal biopsy --- Allograft --- Pathology --- Iraq.


Article
Clinicopathological Spectrum of Renal Biopsies in Children a Multicenter Study in Baghdad-Iraq

Author: Mohamed Saad Fadhil
Journal: Karbala Journal of Medicine مجلة كربلاء الطبية ISSN: 19905483 Year: 2017 Volume: 10 Issue: 1 Pages: 2641-2649
Publisher: Kerbala University جامعة كربلاء

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Abstract

background: Renal biopsy is a very important diagnostic tool for many kidney diseases which play important role in the diagnosis, management and prognosis of kidney diseases.Aim of study: To study the indications, histopathological findings, and complications of renal biopsies in multicenter in Baghdad-Iraq. Materials and Methods: In this retrospective and descriptive study, we included renal biopsies done in multicenter in Baghdad-Iraq, from 1st of January 2014 to 31 of December 2016, which was 120 patients up to 17 years of ageResults: Out of 120 patients, 68 cases (56.6%) were males, and 52 cases (43.3%) were females, steroid resistant nephrotic syndrome was the main indication of renal biopsy 42% followed by acute glomerulonephritis 19% and then evidence of systemic lupus erythematosus 15%, minimal change nephrotic syndrome was the most common primary kidney disease 39% followed by focal segmental glomerulosclerosis 31%. And lupus nephritis was the most common secondary kidney disease 83%, hematuria and mild pain at site of biopsy was the most common complications of renal biopsy 31.4% and 40% respectively.Conclusion: Renal biopsy is useful in diagnosis, assess level of chronicity, management, and prognosis of kidney diseases. Steroid resistant nephrotic syndrome remain the most common indication for renal biopsy, minimal change disease and focal segmental glomerulosclerosis is the most common histopathological lesions in primary kidney diseases, lupus nephritis is the most common secondary kidney diseases. Renal biopsy under ultrasound guidance is safe with self-limited complications in form of hematuria and mild pain at site of biopsy.

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