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The Effect of Fixed Space Maintainer Appliances on Salivary Level of Immunoglobulin A and other Saliva Properties

Author: Esra Hassan Abd Ali1 , Maha Abdul- Kareem Mahmood1
Journal: Iraqi Journal of Biotechnology المجلة العراقية للتقانات الحياتية ISSN: 18154794 Year: 2015 Volume: 14 Issue: 1 Pages: 99-106
Publisher: Baghdad University جامعة بغداد

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Abstract

Abstract: Secretary immunoglobulin A SIgA , play an important role in mucosal immunity, and the salivary level change in response to infection ,social , psychological and physical stress, also the change in level of salivary IgA and other saliva properties include salivary pH, salivary flow rate SFR, and body mass index BMI in children with fixed appliances were measured .The aim of this work was to compare the values of SIgA, PH, SFR and BMI in children with and without fixed appliances. This work included 20 children (10 males and 10 females) with mean age 6 years old who were users of fixed space maintainer for at least 12 weeks, and 20 children (12 males and 8 females) without fixed appliances and with mean age = 6.7 years. The level of SIgA in saliva were assessed by ELISA test. The results revealed that the mean values of SIgA and SFR were higher in fixed appliance group than the group without fixed appliance, with statistical significant difference, but no statistical significant differences were reported for salivary pH and BMI between the studied groups. The results also showed a weak positive correlation between SIgA and SFR (r = 0.07) while negative correlation between SIgA and pH in fixed appliance children (r = 0.1). In conclusion, children with fixed appliances associated with high level of SIgA and SFR and the level of salivary pH and BMI do not correlated with fixed appliance.


Article
The effect of oral contraceptive on the oral health with the evaluation of Salivary IgA and Streptococcus Mutans in some Iraqi women

Authors: Dr. Nebal Thabit Shaker, M.Sc., Assist. lecturer د. نبيل ثابت شاكر --- Dr. Esra Hassan Abd-Ali, PhD., Lecturer د. اسراء حسن عبد علي
Journal: MUSTANSIRIA DENTAL JOURNAL مجلة المستنصرية لطب الاسنان ISSN: 18138500 Year: 2013 Volume: 10 Issue: 1 Pages: 52-63
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Aim: To assess if there is any effect of using oral contraceptive and the duration ofusing on the inflammatory responses of the gingival tissues , concentration ofsecretary immunoglobulin A ( IgA) and the colony count of mutansStreptococcusMS in saliva .Methods: This study includes 80 women in their reproductive age (16-40) year. 40women who were using oral contraceptive in different duration, as the study groupand 40 women who not used oral contraceptive and it were assigned to the controlgroup. Both groups were clinically examined (for dental caries using DMFSIndex, and gingival condition using gingival index GI of Loe&Silness ) andlaboratory assessment (by using non stimulated saliva for each woman wascollected and homogenized then Mutans Streptococci (MS) were counted,isolated, purified and diagnosed according to morphological characteristic andbiochemical tests also, the Salivary IgA concentration was measured by usingsingle radial immune diffusion method in different duration of oral contraceptiveusing ).Results: Gingival index was significantly higher among oral contraceptive users thannon-users (P<0.01), which was correlated with the duration of usage (r=0.50).sIgA concentration higher in study group than in control group (P<0.01)which also increased positively with duration of using(r=0.80). A positivecorrelation between sIgA and gingivitis (r=0.54) was found. DMFS Index and thenumber of MS colony were highly significant in study group than the control(P<0.01). MS colony count was positive correlated with duration of usage(r=0.88) but the DMFS had too weak correlation with the duration of using whichwas a non significant at (P>0.05).Conclusion: The use of contraceptive pills for a long period increases the likelihoodof gingival inflammation and significantly associated with increase sIgA level, sothe regular use of oral contraceptive seems to enhance mucosal immune functionin study subjects.

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