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A prospective study on the effect of waist circumference on symptom severity of gastroesophageal reflux disease
دراسة مستقبلية حول تأثير محيط الخصر على شدة أعراض مرض ارتداد المعدي المريئي

Authors: Nuri Baderkhan Saeed Ahmed --- Muhammed Mustafa Kamal --- Sabah Jalal Shareef
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2016 Volume: 20 Issue: 3 Pages: 1531-1535
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objective: Gastro esophageal reflux disease is one of the commonest gastrointestinal diseases and its incidence is increasing. There is a real challenge in diagnosis and treatment because of its complication if untreated and its effect on patient daily performance. We tried to find the relation between this disease severity symptom known by the number of heartburn attacks per week and (waist circumference).Methods: A cross-sectional study of 100 patients (55% female and 45% male) diagnosed with gastro esophageal reflux disease in Rizgary Teaching Hospital Erbil city from January 2014 to June 2014. Their ages ranged from 17 to 75 years. The criteria for patient selection depended on history and clinical examination and endoscopy, waist circumference measured with a tape measure in centimeter.Results: The mean age ± SD of participants, was 37.13 ± 12.5 ranged from 17-75 years. Regarding the relation between frequency of heartburn attacks and waist circumflex, the study revealed that the number of heartburn attacks was significantly increasing with increasing waist circumflex, (P <0.001), indicating that there is a strong relation between the increase in waist circumflex and severity of gastro esophageal reflux disease symptoms. Conclusion: Increasing of body weight especially waist circumference increases acid exposure to the esophagus. This affects on gastro esophageal reflux disease symptoms severity and its complication. That is why decreasing body weight should be the first line of treatment which will decrease future complication.


Article
Prospective study on effect of Helicobacter pylori on gastroesophageal reflux disease
دراسة مستقبلية عن تأثير هيليكوباكتر بايلوري على مرض الجزر المعدي المريئي

Author: Sabah Jalal Shareef
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2017 Volume: 21 Issue: 2 Pages: 1696-1700
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objective: The Helicobacter pylori infections role in etiology of peptic ulcer is well known, but its role in gastroesophageal reflux disease is one of the important issues which has to be confirmed. We tried to find out the effect of Helicobacter pylori infection on gastroesophageal reflux disease.Methods: The current study was done on 100 patients with gastroesophageal reflux disease from January 1st to June 30th, 2014 in Rizgary Teaching Hospital, Erbil city. The diagnosis was made by history, clinical examination, and endoscopy. Helicobacter pylori infection was confirmed by gastric biopsy and histopathological examination. We tried to find out the effects of Helicobacter pylori infection in gastroesophageal reflux disease patients and its eradication on their symptoms. The data was analyzed with the statistical package for the social sciences (version 18).Results: The mean age ± SD of participants was 37.13 ± 12.5 (17-75 years). The prevalence of Helicobacter pylori infection was 75%. The endoscopy showed that 50 out of 75 patients had erosive esophagitis and 25 out of 75 patients had normal appearance known as non-erosive esophagitis. The study showed no significance of its eradication on symptoms of gastroesophageal reflux disease.Conclusion: The effect of Helicobacter pylori infection in gastroesophageal reflux disease patients was significant regarding endoscopic finding while inversely related to symptoms severity. The eradication of infection did not cause improvement in symptom severity i.e. triple therapy not advised in the course of treatment.

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