research centers


Search results: Found 10

Listing 1 - 10 of 10
Sort by

Article
Cytological Features of Oral Cytobrush Smears in Type II Diabetes Mellitus Patients

Authors: Balkees T. Garib --- Mohammad T. Ahmed محمد طه احمد
Journal: Tikrit Journal for Dental Sciences مجلة تكريت لعلوم طب الاسنان ISSN: 20731213 Year: 2012 Volume: 1 Issue: 2 Pages: 6-12
Publisher: Tikrit University جامعة تكريت

Loading...
Loading...
Abstract

Oral cytology is a renewed field that aids in diagnosis and observation of possible epithelial changes associated with oral mucosal diseases. Aim; to study the main cytomorphological alteration in gingival and buccal smears from type II diabetics in relation to their hyperglycemic status. The study includes 40 type II diabetic patients (20 new-diagnosed and 20 treated diabetics patients) and 20 healthy persons of both sex. Papanicolaou stained smear were prepared from their cheek and gingiva. The morphological features of 100 unfolded epithelial cells were evaluated under light microscope. Results of this study show that diabetics’ oral mucosa cells characterized by large nuclei with frequent evidence of binucleation, granular chromatin, prominent nucleoli. However, there was frequent small blue cytoplasm and buccal smears showed altered keratinization. As conclusion oral cytology from type II diabetics is associated with detectable cytomorphological changes that is site specific and indicate epithelial cell regeneration and degeneration with altered keratinization especially in buccal mucosa.


Article
Oral signs and symptoms and hyperglycemic status of type II diabetic patients in relation to cytomorphometric findings of gingival and buccal cytobrush smears

Authors: Mohammad T. Baban محمد بابان --- Balkees T. Garib بلقيس غريب
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2013 Volume: 25 Issue: 2 Pages: 59-65
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Brush cytology is an accepted technique that gets renewed interest. It is now used as an aid for thediagnosis and observation of possible epithelial changes that could be associated with oral mucosal diseases. Thisstudy aimed to evaluate the cytomorphometric changes in gingiva and buccal mucosa of type II diabetics and toassess their relation to oral symptoms and glycemic status.Materials and methods: Cytological Papanicolaou stained smear were prepared from cheek and gingiva of 20 nontreated cases, 20 treated diabetics and 20 healthy persons of both sex after measuring their HbA1c and recordingtheir oral symptoms. Hundred unfolded epithelial cells were evaluated qualitatively using MCID software to measurenuclear and cytoplasmic areas, ratio, perimeters, and form factors. Different statistical analyses were used todetermine relations between studied parameters.Results: Diabetics smears showed large nucleus, small cytoplasm, and small cytoplasm/nucleus ratio compared withhealthy persons with no sex variation. Xerostomia and burning sensation were significantly correlated with nuclearparameters, while HbA1c was significantly correlated with both cytoplasmic and nuclear parameters. Well-controlledpatients showed reduction in nuclear area, but nucleus and cytoplasm form factors were unlike normal.Conclusions: Oral cytology from type II diabetics is associated with detectable cytomorphometric changes that isbetter demonstrated in buccal than gingival mucosa and tend to return partially to their normal values in wellcontrolledpatients, with no sex variation. NA seems to be the main parameter that changed during hyperglycemiaand xerostomia, while both NA and CA were related to burning sensation


Article
Satisfaction of Patients with Type II Diabetes on Health Service in Specialized Center for Endocrinology and Diabetes /Baghdad 2019

Authors: Nazik L Kadium --- Wijdan A Hussein,
Journal: Al-Kindy College Medical Journal مجلة كلية الطب الكندي ISSN: 18109543 Year: 2019 Volume: 15 Issue: 2 Pages: 87-90
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Patient satisfaction is of increasing importance and widely recognized as an important indicator of quality of the medical care. There was no homogeneous definition of patient satisfaction, since satisfaction concerns different aspects of care or settings, as well as care given by various professions.Objective: The objective of this study is to assess the patients’ level of satisfaction with diabetes care and to identify the underlying factors influencing it.Methods: This cross-sectional study had been conducted in the Specialized Center for Diabetes and Endocrinology in Baghdad Al- Rusafa 2018. Where150 type two diabetic patients attending their follow-up were requested to fill the questionnaire. The questionnaire identified patients, doctors, and practice related factors. For statistical analysis of the data, SPSS Version 24 was used, and the Chi-square statistical test was applied, A p-value less than 0.05 was considered statistically significant. Results: The study showed that the overall level of satisfaction was 79.3%. There was a statistically significant association between age group, gender, profession, educational level and marital status where P value 0.001 for all variables.Conclusion: It was concluded from the study that patients’ satisfaction was high. Majority of the diabetic patients were satisfied with health services, the level of satisfaction increases with age, female gender, and married patients, but it decreases with a high level of education and profession. High level of dissatisfaction seen on treatment services


Article
Isolation of Candida albicans from oral cavity of type II diabetic subjects and its relationship to total and differential white blood cell count
عزل Candida albicans من تجويف الفم لمرضى السكري من النوع الثاني وعلاقته بعدد خلايا الدم البيضاء الكلية والتفاضلية

Authors: Chiman Hameed Saeed --- Nawsherwan Sadiq --- Ashti Mohammad Amin
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2014 Volume: 18 Issue: 3 Pages: 833-838
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

Loading...
Loading...
Abstract

Background and objective: It is well known that oral candidiasis increase in many situations, like obesity, debility, leukemia, viral infection, use of certain drugs in addition to diabetes mellitus. The aim of this study was to estimate the prevalence of Candida albicans in the oral cavity of diabetic and non-diabetic subjects and to identify factors predisposing to colonization in the diabetic patient. The variables evaluated include absolute white blood cell counts and differentials, glycosylated hemoglobin levels, serum glucose, blood urea, serum creatinine and duration of diabetes.Methods: One hundred subjects of type II diabetes mellitus and one hundred non-diabetic subjects (control) were studied for isolation of Candida albicans from oral cavity. Further investigations for diabetic group were done regarding serum glucose, HbA1c, and total and differential white blood cell counts.Results: This study showed 56 (56%) out of 100 diabetic subjects and 30 (30%) out of 100 in non-diabetic subjects were found to carry Candida in their oral cavity. In the diabetic group, no relationship was found to total or differential white blood cell count, recent use of antibiotics, serum glucose and HbA1c values. A significant relationship was found in diabetic patients who had chronic renal disease.Conclusion: Colonization of Candida albicans in the oral cavity was found to be higher in diabetic subjects than in non-diabetic. However, glycaemic control in diabetes, total and differential white blood cells were found to bear no relation with carriage of Candida in the oral cavity.


Article
Relationship between type II diabetes mellitus and Helicobacter pylori infection in Erbil city

Authors: Rawaz D. Tawfeeq --- Zahra A. Amin --- Aveen Jalal --- Sayran K. Hama Baiz
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2019 Volume: 23 Issue: 1 Pages: 43-50
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

Loading...
Loading...
Abstract

Background and objective: Type 2 diabetes mellitus is a metabolic disorder characterized by the increase in blood glucose due to insulin resistance or deficiency of insulin. The subjects are more likely to be prone to infection. So, it could be correlated with Helicobacter pylori infection, which means that gastrointestinal inflammation might be affected by uncontrolled glycemic level. This study aimed to examine the correlation of type II diabetes and infection of gastrointestinal in order to illustrate such complication of diabetes mellitus apart from others. Methods: A total of 64 persons from Erbil city participated in this cross-sectional study. They were divided into two groups, each group involving 32 persons. The cases group included those suffering from type II diabetes and were selected by simple random sampling method. The other group included those not possessing any types of disease including diabetes mellitus. Examination of Helicobacter pylori, glycated hemoglobin (HbA1c), besides measuring blood pressure and body mass index were performed for all individual subjects in both groups. Chi-Square and unpaired t-test were used for data analysis. Results: There was a 59% positively Helicobacter pylori in diabetes group whereas there was a 31% positively Helicobacter pylori in non-diabetes mellitus. The difference between the rates of Helicobacter pylori in both groups was statistically significant (P <0.05).Conclusion: The prevalence of Helicobacter pylori infection in diabetics was significantly higher than the non-diabetics.


Article
Corneal Specular Microscopy Changes in Type II Diabetes Mellitus

Authors: Yousif Farhan Dawood --- Najah Kadhum mohammad Al-Quraishi
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2014 Volume: 13 Issue: 4 Pages: 591-598
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

ABSTRACT:BACKGROUND: Corneal endothelial cells count and shape are vital in keeping corneal transparency with normal vision. Diabetes mellitus is associated with significant changes in the corneal endothelium. OBJECTIVE: To compare corneal endothelial structure and central corneal thickness (CCT) between type II diabetics and non-diabetic control patients.METHODS: Specular microscopy was used to measure central corneal thickness (CCT), average size of endothelial cells, standard deviation of cell size and coefficient of variation in cell area (CV), endothelial cell density, as well as hexagonality of 260 eyes from 260 patients ( 130 eyes from type II diabetic patients and 130 eyes from non diabetic controls).RESULTS: The diabetic corneas have a significant increase in average size of endothelial cells (410.4 ± 89.6 µm² vs. 382.3 ± 83.4 µm²)(p <0.05 ), standard deviation of cell size (152.2 ± 38.0 µm² vs. 128.7 ± 19.5 µm²)(p <0.05) and coefficient of variation (CV) (38.3 % ± 5.4 % vs. 33.4 % ± 4.4%)(p<0.05). and a significant decrease of endothelial cell density (2570.7 ± 563.1 cells / mm² vs. 2704.1 ± 572.5 cells / mm²)(p <0.05) and hexagonality (48.3 ± 17.1% vs. 56.5% ±15.6%)(p<0.05). There was no significant difference in central corneal thickness(CCT) (516.3 ± 63.4 µm vs. 512.8 ± 61.7µm )(p >0.05). CONCLUSION: Type II diabetes associated with a significant changes in the corneal endothelium including, reduction of endothelial cell density, increased variation of cells shape (pleomorphism) and increased variation of cells area (polymegathism). There was no significant changes of central corneal thickness (CCT).


Article
Relationship between Serum Lipoprotein Ratios and Insulin Resistance in Iraqi Women with Type II DM

Authors: Maha Fadhil Smaism --- Najla,a Jawad Hassani
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2015 Volume: 12 Issue: 4 Pages: 1137 -1145
Publisher: Babylon University جامعة بابل

Loading...
Loading...
Abstract

Type 2 diabetes confers an increased morbidity and mortality dueto macrovascular complicationssuch as CVDfor which dyslipidemia is themajor contributor. This study was designed toexplore the role of non-HDLcandlipoprotein ratios as CVD riskmarker in diabetic population. It was acase –control study , 68 female uncontrolled (HbA1c ≥ 6.5) diabetic were selected, 34 were diabetic who were treatment(Goup A) and 34 werediabetic without treatment (Group B)and 34 were non-diabetic subjects as control group . The lipidprofile including TC, TG and HDLc were measured and calculation of lipoprotein ratios.Lipoprotein ratios were significantly higher in group A, Non-HDL(P<0.001), TC/HDL and TG/HDL(P<0.01), LDL/HDL(P<0.05) In group B; Non-HDLc(P<0.01), TC/HDL, TG/HDL and LDL/HDL(P<0.05) in contrast tocontrols. There is significantly positive correlation of TG/HDLc, TC/HDLc, LDL/HDLc and Non-HDLc with HOMA-IR in group A and in group B. Lipoprotein ratio provide a simple means of identifying insulin resistance which could be used as a possible risk factor ofCVD in uncontrolledtype 2 diabetic.


Article
Disturbance of Arginase Activity and Nitric Oxide Levels in Iraqi Type 2 Diabetes Mellitus
اضطراب نشاط ألارجينيز ومستويات أوكسيد النيتريك في المرضى العراقيين بداء السكري النوع الثاني

Authors: Fayhaa.M.Khaleel فيحاء مقداد خليل --- Noor N- Oda نور نايف عودة --- Baaydaa A. Abed بيداء احمد عبد
Journal: Baghdad Science Journal مجلة بغداد للعلوم ISSN: 20788665 24117986 Year: 2018 Volume: 15 Issue: 2 Pages: 189-191
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

This study is an attempt to find whether arginine metabolism dysregulation by arginase activity is related to hyperglycemia, followed by changes in nitric oxide (NO) generation in type 2 diabetic patients. This study includes 42 control subjects (Group I), and 92 Iraqi patients with type 2 diabetes mellitus (T2DM). The patient group was subdivided into two groups: Group II (54) with T2DM only and Group III (38) with T2DM and dyslipidemia (who were treating with atorvastatin along with diabetes treatment). The samples were obtained to measure arginase activity and NO levels. Serum arginase activity increased significantly in patients(groupII and groupIII) compared to control group. While serum NO level was significantly lower in diabetic patients as compared to control group, three significant correlations appeared in this study between glucose and arginase activity, glucose and NO levels, and between arginase activity and NO levels. The results also show that treatment with atorvastatin affects arginase activity and NO levels. Increasing in levels of arginase activity can be considered as an indicator of diabetic status. Endothelial dysfunctions accompanied with diabetes mellitus reverses correlation between arginase and NO in diabetic.

في هذه الدراسه تمت محاولة ايجاد فيما اذا كان الخلل الحاصل في تنضيم ايض الحامض الاميني الارجينين (بواسة انزيم الارجنيز) له علاقه بأرتفاع مستوى السكر بالدم متبوعا بتغيرات تخليق اوكسيد النايتريك(NO). تضمنت الدراسه (42) عينه من الاصحاء (مجموعه I ) و (92) عينه من المرضى العراقيين بداء السكري النوع الثاني.تم تقسيم عينات المرضى الى مجموعتين : مجموعه (II)تتضمن (54) عينه من المرضى المصابين بالسكري فقط , و المجموعه الثانيه (III) تتضمن (38) عينه من المرضى المصابين بداء السكري و اضراب مستويات الدهون بالدم (dyslipidemia) ( و الذين يخضعون لعلاج الستاتين اضافه الى علاج السكري). تم قياس مستويات فعالية انزيم الارجنيز و اوكسيد النايتريك في السيرم لجميع العينات. اظهرت النتائج ارتفاعا معنويا لقيم فعالية الانزيم في مجاميع المرضى مقارنة بمجموعة الاصحاء بينما اظهرت انخفاضا معنويا بمستويات اوكسيد النايتريك بمجاميع المرضى بالنسبة الى مجموعة الاصحاء. في هذه الدراسه ظهرت ثلاث علاقات معنويه تربط بين مستوى السكر و فعالية الانزيم, مستوى السكر و مستوى اوكسيد النايتريك, و بين فعالية الانزيم و مستوى اوكسيد النايتريك, كما اظهرت النتائج ان الستاتين له تأثير على على مستويات كل من فعالية الانزيم و اوكسيد النايتريك.


Article
Quality of Life of Patients with Type II Diabetes Mellitus in Al- Hilla City-Iraq
نمط حياة مرضى السكر النوع الثاني في مدينة الحلة – العراق

Loading...
Loading...
Abstract

Diabetes mellitus is a global problem nowadays due to increase the disease cases all over the world, in both the developed and developing countries which may affect the quality of life (QOL ) of diabetic patients. This study was conducted to assess the quality of life of patients with type 2 diabetes mellitus (DM) and to determine some selected clinical and sociodemographic factors that affect the quality of life of these patients in Al Hila city-Iraq. This was a cross sectional study in which 100 patients with type 2 diabetes mellitus attending diabetic outpatient clinics of Merjan Teaching Hospital-Al Hila. To assess the quality of life of those diabetic patients, the World Health Organizations Quality of Life Assessment (WHOQOL) was applied, but in a short version questionnaire and abbreviated form called (WHOQOL-BREF).Concerning the results of this study, it was found that the patients responded fairly well on the questionnaire used, 39% had good score, 47% had fair score and 14% had poor score. For physical health domain 17% had poor score, for social domain 22% had poor score, for psychological domain 19% and environmental domain 18% had poor score.It was concluded from the results that although it supports previous reports in which QOL of patients with DM were fairly good but this disease is significantly affects physical health, social relations and environment. Furthermore, there is association with marked impairment in aspects of quality of life relating to mental health and psycho-social functioning and at least some aspects of physical health. Given this, and given its high prevalence, greater attention is needed to watch DM as a public health problem. The fact that DM is “normative” should not be taken to infer that it is benign.

من الممكن اعتبار تزايد حالات الاصابه بمرض السكري هذه الايام كمشكله عالميه يعاني منها العالم اجمع،، ويكمن التأثير الأساسي لهذا المرض في التغيرات التي يحدثها مرض السكري في أسلوب وجودة نوعية الحياة في جميع المجالات وخاصة المجال البدني، الاجتماعي والعاطفي.صممت هذه الدراسه لتقييم نوعية الحياة لمرضى السكري من النمط 2 وتحديد العوامل السريرية والاجتماعية والسكانية التي تؤثر على نوعية الحياة لهؤلاء المرضى. فقد شملت الدراسة 100مريض من مراجعي العيادة الخارجية للسكري في مستشفى مرجان التعليمي في مدينة الحله وقيّمت نوعية الحياة باستخدام استمارة استبيان لمنظمة الصحة العالمية.خلصت نتائج الدراسة أنه بصورة عامة 39% من المرضى يملكون نوعية حياة جيدة و 47% متوسطة و 14% رديئة. بالنسبة للنشاط البدني كانت رديئة عند 17% من المرضى، وان العلاقات الاجتماعية كانت رديئه عند 22 % من المرضى، أما بالنسبة للوضع النفسي فكانت رديئه عند 19%منهم , والبيئي فكانت نوعية الحياة عندهم رديئه بنسبة 18 % من المرضى.من خلال النتائج التي توصلت اليها الدراسه،، من الممكن اعتبار بانه بالرغم من ان نوعية الحياة لمرضى السكري في بلدنا تعتبر جيده. لكن الناحية البدنية والاجتماعيه والنفسية و البيئية فقد تأثرت بشكل ملحوظ فضلا عن ذلك ارتباط السكري بالضرر البالغ في أوجه نوعية الحياة المتعلقة بالصحة العقلية والوظائف الأجتماعية والنفسية وبدرجة أقل الأوجه المتعلقة بالصحة البدنية. ونتيجة لذلك ولانتشار مرض السكري الكبير في العالم ، يوجب أن يعطى اهتمام أكبر للسكري بأعتباره مشكلة صحة عامة.


Article
Serum leptin and 25 Hydroxyvitamin D levels in patients with type II diabetes mellitus
مستوى اللبتين و 25 هيدروكسي فيتامين د في مصل المرضى المصابين بداء السكري النوع الثاني

Authors: Thana I Mustafa ثناء اسماعيل مصطفى --- Basil O Saleh ا. د باسل عويد صالح --- Abid A Thaker ا. د عبد علي ذاكر
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 / 24108057 Year: 2017 Volume: 59 Issue: 2 Pages: 156-159
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Vitamin D and Leptin appears to play a range of roles in beta cell growth and insulin secretion and most importantly interaction with other hormonal mediators and regulators of energy and metabolism. Objective: The aim of this study was to measure serum leptin and vitamin D levels and to investigate their relationships with vitamin D and other clinical laboratory parameters in patients with type II diabetes. Subjects and Methods: Blood samples were taken from 80 patients with type II diabetes mellitus encountered during their attending the Internal Medicine clinic consultancy in Ramadi Teaching Hospital and the National Diabetes Center for Treatment and Research at Al-Mustansiriya University and 60 healthy subject. From December 2014 to November 2015. Investigations included serum Leptin, 25OHD, Insulin, HbA1c using ELISA and biochemical test.Results: The median concentration of serum 25 OH vitamin D of patients (15.70 ng/ ml) was significantly lower than healthy controls (20.27 ng/ ml). The rate of vitamin D deficiency (VDD) was significantly higher in patients (82.5%) than healthy controls (48.3%). The serum insulin and HOMA-IR were significant increase in patients had vitamin D < 20 ng/ml when compared with an insufficient/normal group. There were no significant differences in leptin levels between type II DM and healthy control. Conclusion: These results strongly support the role of vitamin D deficiency and serum leptin in pathogenesis of type II diabetes.

خلفية البحث: يلعب اللبتين وفيتامين د مجموعة من الادوار في نمو خلايا بيتا وافراز الانسولين والاهم من ذلك التفاعل مع الهرمونات الاخرى المنظمةللطاقة والايض.اهداف البحث: تهدف الدراسة قياس مستوى فيتامين د واللبتين في مصل دم مرضى النوع الثاني من السكري والتحقق في علاقتهم مع فيتامين د وغيرهامن المعالم السريرية والمختبرية في المرضى المصابين بداء السكري النوع الثاني.العينة والطرائق : أخذت عينات الدم من 80 مريضا بداء السكري النوع الثاني أثناء حضورهم العيادة الاستشارية الطب الباطني في مستشفى الرماديالتعليمي والمركز الوطني لعلاج و بحوث السكري / مستشفى اليرموك التعليمي و 60 من الاشخاص الاصحاء من كانون الاول/ 2014 الى تشرينالثاني/ 2015 . وتضمنت القياسات فيتامين د، هرمون اللبتين و الانسولين ، نسبة السكر المخزون في خضاب الدم باستخدام تقنية الاليزا واختباراتالكيمياء الحيويةالنتائج: انخفض المستوى المصلي لتركيز فيتامين د انخفاضا معنويا لدى المرضى المصابين بداء السكري النوع الثاني ) ng/ml 15.70 ( مقارنة معالضوابط الصحية ) 20.27 نانوغرام/مل(. معدل نقص فيتامين د ) VDD ( كان أعلى بكثير في مرضى السكري النوع الثاني ) 82.5 %( مقارنة معالضوابط الصحية ) 48.3 %(. ارتفع معنويا المستوى المصلي لتركيز هرمون الانسولين ومقاومة الانسولين لدى مرضى السكري الذين لديهم تركيزفيتامين د اقل من 20 نانوغرام مقارنة مع المرضى الذين لديهم كمية كافية او طبيعة من فيتامين د. لم يظهر هناك اختلاف معنوي في تركيز هرموناللبتين بين المرضى والضوابط الصحيةالاستنتاج : تدعم هذه النتائج دور نقص فيتامين د واللبتين في امراض النوع الثاني من داء السكري.

Listing 1 - 10 of 10
Sort by
Narrow your search

Resource type

article (10)


Language

English (9)

Arabic and English (1)


Year
From To Submit

2019 (2)

2018 (1)

2017 (1)

2015 (1)

2014 (3)

More...