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Article
Preparation of Anise and Thyme Lotion for Topical Use

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Abstract

Anise and thyme crude extract were used to prepare a lotion for topical application due to their antimicrobial, germicidal and antifungal effects. Two formulas were prepared using the mentioned natural plants, formula 2 (selected lotion) was the most acceptable one which contained veegum and xanthan gum as suspending agents in addition to other exceipients providing it good properties with high physical stability because of its flocculating, pouring, resuspending easily with sedimentation volume (F) 0.96. In addition to unchangeable odor and color with expiration date of one year. While the Preliminary clinical study was done using this lotion on 10 patients with infecious viral skin diseases, it was found that this lotion was successful as a topical preparation for allergy and mostly chicken pox.

أستخدم المستخلص الخام لمادتي الينسون والزعتر لتحضير غسول للاستعمال الخارجي بسبب فعالية تلك المواد في قتل البكتريا، الجراثيم والفطريات. تم تحضير غسولين باستخدام نفس المواد النباتية الخام، كان الغسول الثاني المحضر (الصيغة المختارة) هو الأكثر قبولاً لاحتوائه على مادتي الزانثان والفيكام مع مواد اخرى مضافة والتي اعطت صفات جيدة لهذا الغسول حيث كان ذات ثباتية فيزياوية عالية لكونه لا يتكتل ويعاد توزيع مواده بالرج وله حجم ترسيب 0.96. اضافة الى عدم حدوث تغير في لونه ورائحته مع مدى صلاحيته للاستعمال لمدة سنة واحدة. اما بالنسبة للدراسة السريرية الاولية والتي تمت باستخدام هذا الغسول على عشرة اشخاص مصابين بالتهابات جلدية فايروسية. فقد اثبت نجاحه كمستحضر للاستعمال الخارجي للحكة وخصوصاً مرض الجدري المائي.


Article
Evaluation of the Antimicrobial Effect of Ethanolic Extracts of Sage and Rue as a Root Canal Irrigants (An In Vivo Study).

Author: Maha M Al –Bazzaz
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2011 Volume: 11 Issue: 2 Pages: 310-316
Publisher: Mosul University جامعة الموصل

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Abstract

Aims: To evaluate the antimicrobial effect of the ethanolic extracts of Ruta graveolens (Rue) and Sal-via officinalis (Sage) in a concentration of 0.2% and compare the results with the same concentration of chlorhexidine 0.2% (CHX) and normal saline on root canal bacteria using the above plant extracts as an irrigating solutions clinically. Materials and Methods: Thirty five uniradicular teeth with necrotic pulps were chosen. The patients were divided randomly into four groups, 10 patients for groups I, II and III and 5 patients for group IV. Using 0.2% ethanolic extract of Sage, 0.2% ethanolic extract of Rue, 0.2% chlorhexidine gluconate (CHX) and normal saline, respectively. Samples were obtained from the canal at the beginning of the first and second appointments, at the end of the second appoint-ment and at the beginning of the third appointment using wet sterile paper points. Results: The results revealed that 0.2% of the ethanolic extract of both Sage and Rue have a significant antimicrobial effect when used clinically as an endodontic irrigant, and was significantly not different from 0.2% chlorhex-idine gluconate (CHX) and significantly different from normal saline. Conclusions: Rue and Sage demonstrated antimicrobial effects on the root canal bacteria (both aerobic and anaerobic) used as en-dodontic irrigants compared with CHX.


Article
The antimicrobial effect of water extraction of Salvadora persica (Miswak) as a root canal irrigant

Authors: Talal H Al–Salman --- Moataz Gh Al–Shaekh Ali --- Osama M Al–Nu’aimy
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2005 Volume: 5 Issue: 1 Pages: 33-36
Publisher: Mosul University جامعة الموصل

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Abstract

The aim of this study was to evaluate the antimicrobialeffect of 10% water extraction of Salvadora persica (Miswak)when used clinically as an endodontic irrigant.Twenty four uniradicular teeth with necrotic pulps werechosen. The patients were divided randomly into 2 groups:Experimental group, in which water extract of Salvadorapersica (10%) was used as a root canal irrigant; and controlgroup, in which distilled water was used as a root canal irrigant.Bacteriological samples were obtained from the canal atthe step of working length determination (before the canalwas subjected to instrumentation and irrigation procedures),and at the end of the biomechanical instrumentation proceduresby using a sterile K–file. The file was separated from thehandle using a sterile wire cutter, and the severed portion wasplaced in a sterile screw–capped vial containing 5 ml of thioglycollatebroth as a transport media. A 0.1 ml of thioglycollatebroth was inoculated on each of two brain–heart infusionagar plates: One plate was incubated under aerobic conditions,and the other was incubated under anaerobic conditionsusing anaerobic jar and gas pack anaerobic system. Both plateswere incubated at 37 ºC for 24 hours; then, the number ofbacterial colonies was counted.The results revealed that 10% water extraction of Salvadorapersica is an effective antimicrobial agent when utilizedclinically as an irrigant in the endodontic treatment of teethwith necrotic pulps.


Article
An Antimicrobial Activity of Moringa Oleifera Extract in Comparison to Chlorhexidine Gluconate (In vitro study)

Authors: Khulood Majid Alsaraf خلود مجيد الصراف --- Suha T. Abd --- Nada S. Husain
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2016 Volume: 28 Issue: 1 Pages: 183-187
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Oral diseases persist to be a major health problem all over the world. Various bacteria and fungi arefound to be the possible pathogensresponsible for the oral diseases. Moringa oleifera it is an extraordinary nutritiousvegetable tree with many different uses. These leaves have high medicinal value. In the present study, antibacterialand antifungal activities of aqueous extracts of plant Moringa oleifera in comparison to chlorohexidene gluconateand deionized water were determined.Materials and methods: The leaves of plant of Moringa oleifera were collected from College of Pharmacy; Baghdad,Iraq. Tested microorganism (bacterial and fungal) was isolated from different clinical specimens. In-vitroantimicrobialactivity was performed by agar well diffusion method on Muller Hinton agar medium.Results: The water extract of Moringa oleiferashowed antibacterial effect on the tested organisms: Staphylococcusaureus, Streptococcus spp. and Enterococcus faecalis. Aqueous extract showed maximum zone of inhibition againstS.aureus.Conclusion: Moringa olifera can be used as safe and cheap plant antimicrobial agent


Article
Antibacterials activity from agaricus bisporus on some bacteria isolates
دراسة للفعالية التثبيطية للفطر ضد بعض العزلات البكتيريAgaricus bisporus

Author: ban musa hassan al-zubaidi بان موسى حسن الزبيدي
Journal: Albahir journal مجلة الباهر ISSN: 23125721 Year: 2015 Volume: 2 Issue: 3,4 Pages: 71-79
Publisher: AL-Abbas Holy Shrine العتبة العباسية المقدسة

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Abstract

Abstract The antimicrobial properties of cold water, hot water, ethanol and aceton extracts of mushroom Agaricus bisporus on some gram positive bacteria (Staphylococcus aureus, Streptococcus pneumonia, Bacillus cereus), gram negative bactaria (Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi) were investigated the present showed that aceton extract (50 mg/ml) exhibited maximum antibacterial activity to all bactaria isolated. Its showed wide spectrum of antimicrobial effect against Streptococcus pneumonia (31.6 mm), Escherichia coli (27.4 mm), Bacillus cereus (12 mm), Salmonella typhi (20.6 mm), Staphylococcus aureus (18 mm), Pseudomonas aeruginosa (10.2 mm). The minimum inhibitory concentration (MIC) reached 6.25 mg/ml for positive bacteria and 12.5 mg/ml for negative bacteria while the (MBC) reached 12.5 mg/ml for positive bacteria and 25 mg/ml for negative bacteria except Pseudomonas aeruginosa were reached (MIC) 25mg/ml anD (MBC) 50 mg/ml.

اﳋلاﺻة ﺍﳌﺎﺋﻴﺔ )ﻣﺎﺀ ﺑﺎﺭﺩ، ﻣﺎﺀ ﺣﺎﺭ( ﻭﺍﻟﻜﺤﻮﻟﻴﺔ (Agaricus bisporus)ﺗﻢ ﰲ ﻫﺬﺍ ﺍﻟﺒﺤﺚ ﺩﺭﺍﺳﺔ ﺗﺄﺛﲑ ﻣﺴﺘﺨﻠﺼﺎﺕ ﺍﻟﻔﻄﺮ (Escherichia coli, Pseudomonas)ﺃﻳﺜﺎﻧﻮﻝ، ﺃﺳﻴﺘﻮﻥ( ﺿﺪ ﺳﺘﺔ ﺃﻧﻮﺍﻉ ﻣﻦ ﺍﻟﺒﻜﱰﻳﺎ ﺛﻼﺛﺔ ﻣﻨﻬﺎ ﺳﺎﻟﺒﺔ ﻟﺼﺒﻐﺔ ﻏﺮﺍﻡ (Bacillus cereus, Staphylococcus. ﻭﺛﻼﺛﺔ ﺃﺧﺮ￯ ﻣﻮﺟﺒﺔ ﻟﺼﺒﻐﺔ ﻏﺮﺍﻡ aeruginosa,Salmonella typhi) ﻭﻗﺪ ﺃﻇﻬﺮﺕ ﲨﻴﻊ ﺍﳌﺴﺘﺨﻠﺼﺎﺕ ﺍﳌﺎﺋﻴﺔ ﻭﺍﻟﻜﺤﻮﻟﻴﺔ ﺗﺄﺛﲑ ﺗﺜﺒﻴﻄﻲ ﻛﺒﲑ ﺿﺪ aureus, Streptococcus pneumonia) )ﻣﻠﻐﻢ/ﻣﻞ( ﺃﻋﲆ ﻧﺴﺒﺔ ﺗﺜﺒﻴﻂ ﻟﻜﻞ ﺍﻷﻧﻮﺍﻉ 50ﻛﻞ ﺍﻷﻧﻮﺍﻉ ﺍﻟﺒﻜﺘﲑﻳﺔ ﺍﳌﺪﺭﻭﺳﺔ، ﺳﺠﻞ ﺍﳌﺴﺘﺨﻠﺺ ﺍﻷﺳﻴﺘﻮﲏ ﻭﺑﱰﻛﻴﺰ ﺿﺪ ﺑﻜﱰﻳﺎ (Streptococcus pneumonia) )ﻣﻠﻢ(، 27.4 )ﻣﻠﻢ( ﺿﺪ ﺑﻜﱰﻳﺎ 31.6ﺍﻟﺒﻜﺘﲑﻳﺔ ﺃﺫ ﺑﻠﻎ ﻗﻄﺮ ﻣﻨﻄﻘﺔ ﺍﻟﺘﺜﺒﻴﻂ ﺗﻠﺘﻬﺎ Salmonella typhi ﲡﺎﻩ ﺑﻜﱰﻳﺎ (Bacillus cereus) )ﻣﻠﻢ(، 20.6 ﲡﺎﻩ ﺑﻜﱰﻳﺎ (Escherichia coli) )ﻣﻠﻢ(، 21 ﺃﻗﻞ Pseudomonas aeruginosa )ﻣﻠﻢ( ﺑﻴﻨﲈ ﺳﺠﻠﺖ ﺑﻜﱰﻳﺎ 18 ﺑﻘﻄﺮ ﺗﺜﺒﻴﻂ ﻗﺪﺭﻩ Staphylococcus aureusﺑﻜﱰﻳﺎ MBC ﻭﺍﻟﱰﻛﻴﺰ ﺍﻟﻘﺎﺗﻞ MIC )ﻣﻠﻢ(، ﻭﻛﺬﻟﻚ ﺃﻇﻬﺮﺕ ﺍﻟﻨﺘﺎﺋﺞ ﺃﻥ ﻗﻴﻤﺔ ﺍﻟﱰﻛﻴﺰ ﺍﳌﺜﺒﻂ ﺍﻷﺩﻧﻰ 10.2ﻗﻄﺮ ﺗﺜﺒﻴﻂ ﻭﻗﺪﺭﻩ )ﻣﻠﻐﻢ/ﻣﻞ( 12.5 )ﻣﻠﻐﻢ/ﻣﻞ(، 6.25ﻟﻠﻤﺴﺘﺨﻠﺺ ﺍﻷﺳﻴﺘﻮﲏ ﺿﺪ ﺍﻷﻧﻮﺍﻉ ﺍﻟﺒﻜﺘﲑﻳﺔ ﺍﳌﻮﺟﺒﺔ ﻟﺼﺒﻐﺔ ﻏﺮﺍﻡ ﺍﳌﺪﺭﻭﺳﺔﻫﻲ )ﻣﻠﻐﻢ/12.5 ﻗﺪﺭﻩ MICﻟﻠﱰﻛﻴﺰﻳﻦ ﻋﲆ ﺍﻟﺘﻮﺍﱄ ﺑﻴﻨﲈ ﺳﺠﻠﺖ ﺍﻷﻧﻮﺍﻉ ﺍﻟﺒﻜﺘﲑﻳﺔ ﺍﻟﺴﺎﻟﺒﺔ ﻟﺼﺒﻐﺔ ﻏﺮﺍﻡ ﺗﺮﻛﻴﺰ ﻣﺜﺒﻂ ﺃﺩﻧﻰ )ﻣﻠﻐﻢ/25 ﺍﻟﺘﻲ ﺳﺠﻠﺖ Pseudomonas aeruginosa )ﻣﻠﻐﻢ/ﻣﻞ(، ﻣﺎﻋﺪﺍ ﺑﻜﱰﻳﺎ 25 ﻗﺪﺭﻩ MBCﻣﻞ( ﻭﺗﺮﻛﻴﺰ ﻗﺎﺗﻞ )ﻣﻠﻐﻢ/ﻣﻞ( ﻟﻠﱰﻛﻴﺰﻳﻦ ﻋﲆ ﺍﻟﺘﻮﺍﱄ


Article
The Study of Antibacterial Effects of Combining Some Medicinal Plants with Certain Antibiotics Against the Multidrug-Resistant E. coli.
دراسة التأثير المضاد البكتيري لخلط بعض النباتات الطبية مع بعض المضادات على بكتريا ال E. coli المقاومة للمضادات المتعددة.

Authors: Wi'aam Abid Jwair وئام عبد جوير --- Ausama N. Najris اسامة ناظم نجرس
Journal: Tikrit Journal for Agricultural Sciences مجلة تكريت للعلوم الزراعية ISSN: 18131646 Year: 2019 Volume: 19 Issue: 2 Pages: 84-92
Publisher: Tikrit University جامعة تكريت

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Abstract

As resistant microorganisms are causing a serious global problem, medicinal plants had begun to draw scientists' attention to use them as alternative medicines or in case of this research; to be combined with antibiotics to find a solution against one of these resistant microorganisms. This research shows the possibility of getting positive results in inhibiting the growth of Multidrug-resistant E. coli; through the synergism between medicinal plant extracts with antibiotics. Each of the alcoholic and aqueous extract of the plants: Glycyrrhiza glabra, Viscum album and Chamaemelum nobile were combined with Erythromycin ethylsuccinate and Gramicidin in certain percentages individually to get three types of combinations (A, B and C). Combinations that contained more percentages of extracts than antibiotic in them showed the highest synergistic positive results in inhibiting the growth of E. coli. Furthermore, these plant extracts as the phytochemical screening tests showed, contain certain active contents which in rule have antimicrobial effects.

بما أن الكائنات الدقيقة المقاومة سبب لمشكلة عالمية خطيرة، فقد بدأت النباتات الطبية بجذب انتباه العلماء لاستخدامها كأدوية بديلة أو كما في حال هذا البحث لخلطها مع المضادات الحيوية لإيجاد حل ضد أحد هذه الكائنات الدقيقة المقاومة. هذا البحث يبين إمكانية الحصول على نتائج إيجابية في تثبيط نمو بكتريا E. coli المقاومة للأدوية المتعددة عن طريق التآزر بين المستخلصات النباتات الطبية والمضادات الحيوية. تم خلط المستخلصات الكحولية والمائية لكل من نبات عرق السوس Glycyrrhiza glabra والدبق Viscum album والبابونج Chamaemelum nobile مع المضادات الحيوية: Erythromycin ethylsuccinate وGramicidin كل منها على حدى وبنسب معينة للحصول على ثلاث أنواع من التوليفات (ِA وB و C ). التوليفات التي احتوت على نسب أعلى من المستخلصات النباتية مقارنة بنسبة المضادات فيها أظهرت نتائج إيجابية تآزرية أعلى في تثبيط نمو بكتريا ال E. coli . علاوة على ذلك، بينت الكشوفات الكيميائية أن مستخلصات النباتات هذه تحتوي على مكونات فعالة معينة والتي بدورها تمتلك فعالية مضادة للميكروبات.

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