research centers


Search results: Found 2

Listing 1 - 2 of 2
Sort by

Article
The anti-oxidant effect of processed garlic
الفعالية المضادة للتأكسد لحبوب الثوم

Author: Layla Othman Khalid
Journal: KUFA MEDICAL JOURNAL مجلة الكوفة الطبية ISSN: 1993517X Year: 2012 Volume: 15 Issue: 1 Pages: 326-331
Publisher: University of Kufa جامعة الكوفة

Loading...
Loading...
Abstract

Background: Oxidative stress is accepted as a critical pathophysiolog mechanism in different human disorder like cardiovascular diseases, cancer , diabetes mellitus and neurodegenerative diseases, because of accumulation of radical oxygen species (ROS) & radical nitrogen species(RNS).Garlic(Allium Sativum) has been used as a spice & as a medicine in treatment of these diseases because it contains antioxidants & regarded as an effective hydroxyl radical scavenger. In the present work the antioxidant effect of processed garlic was studied by measuring its effect on the level of reduced glutathione (GSH) & malondialdyhyde(MDA).Design of study: Experimental follow up study.Methods & materials: The level of erythrocyte GSH & plasma MDA were measured in 12 apparently healthy volunteers before & every 10 days for 1month during taking garlic tablets.Results: The level of GSH was significantly increased by 31.30%(P<0.01)&MDA level was significantly decreased by 26.42% (P<.0.01) after 30 days of ingestion of garlic tablets..Conclusion: The results suggest that processed garlic has lowering effect on MDA & increasing effect on erythrocytes GSH.

أن الجهد التأكسدي يعتبر سبب لكثير من الأمراض البشريه مثل أمراض جهاز الدوران , السرطان ,داء السكري وأمراض الجهاز العصبي بسبب تجمع جذور حره للأوكسجين وجذور حره للنتروجين.أن الثوم استخدم كبهارات وكدواء لمعالجة هذه الأمراض لأ حتوائه على مضادات التأكسد وللتخلص من الجذور الحره الهيدروكسيليه.الهدف:دراسة الفعاليه المضاده للتأكسد لحبوب الثوم بواسطة قياس تأثيره على مستوى الكلوتاثايون المختزل(GSH) والميلانالديهايد ((MDAطريقة العمل:تم قياس مستوى (MDA)(GSH)ل 12عينة دم لأشخاص أصحاء قبل أستخدام الدواء ثم كل 10 ايام بعد أستخدامه ولمدة30 يوماالنتائج:أوضحت النتائج بوجود علاقه معتده ااحصائيا لمادة MDAوالتي قلت بنسبة 26,42%(P0.01)بعد شهر من استخدام الدواء.وهناك أيضا علاقه معتده أحصائيا لمادة GSH حيث أرتفعت قيمته بنسبة 31,3%(P0.01)بعد شهر من استخدام الدواء.الأستنتاج:ان لحبوب الثوم فعاليه مضاده للتأكسد وذلك عن طريق تأثيره بزيادة الماده المضاده للتأكسد (الكلوتاثايون) وتقليله لمادة الميلانالديهايد الناتجه من تأكسد الدهون.


Article
The therapeutic effect of viscous solution of curcumine in the treatment of recurrent aphthous stomatitis (RAS)

Author: Maha T Al–Saffar
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2006 Volume: 6 Issue: 1 Pages: 48-52
Publisher: Mosul University جامعة الموصل

Loading...
Loading...
Abstract

Aim: To determine the various therapeutic effect of different concentrations of viscous curcumine solution on the healing of ulcer in patients with recurrent aphthous stomatitis (RAS). Materials and Methods: A total of 83 patients with RAS divided into four groups: Group A: Thirty patients received viscous solution of curcumine 10%; Group B: Thirty three patients received viscous solution ofcurcumine 50%; Group C: Ten patients without treatment (control negative); and Group D: Tenpatients received glycerin treatment (control positive). Results: Females were more affected than maleswith RAS (69.9% female and 30.1% male) and upper and lower labial mucosa were the most commonsite of the lesion. The results also showed significant difference between complete healings in patients using viscous solution of curcumine 50% and 10% respectively, and patients without treatment (control negative), while there was no significant difference between the complete healing in patients use 50% of solution and 10 % of the same solution. Conclusion: Topical application of viscous solution of curcumine at 10% and 50% showed a good percentage of complete healing of ulcer in patients with RAS and further study for its effect on other oral lesion may be recommended.

Listing 1 - 2 of 2
Sort by
Narrow your search

Resource type

article (2)


Language

English (2)


Year
From To Submit

2012 (1)

2006 (1)