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Polymer- Nanoparticles Composites for the Reduction of the Bacterial Adherence to Surfaces

Author: Muna Sabbar AL-Rubiae
Journal: Iraqi Journal of Biotechnology المجلة العراقية للتقانات الحياتية ISSN: 18154794 Year: 2016 Volume: 15 Issue: 3 Pages: 17-24
Publisher: Baghdad University جامعة بغداد


The medical device is one of the sources of nosocomial infections; the adherence of the bacteria on the surface of this device is the first step in the medical device related infection. In this study nanocomposite of polymethyl methacrylate (PMMA)/titanium oxide nanoparticles (1, 5, 10, 20, 30 wt %) and copolymer acrylonitrile butadiene styrene (ABS)/titanium oxide nanoparticles (1, 5, 10, 20, 30 wt %) were used to investigate the ability of the nanocomposite for the reduction of the bacterial adherence to the surfaces. The microorganisms which is used in this study include (Pseudomonas aeruginosa, Staphylococcus aureus and Klebsiella pneumonia). After an incubation of microorganisms with nanocomposites for 2 hours, it was found that the adhered bacterial cells were significantly reduced on all of the TiO2-containing nanocomposites in the comparison with control polymer. The reduction is reached to 60.82% with10% TiO2 in ABS for P. aeruginosa. The results of the S. aureus adherence on nanocomposite are revealed a significant reduction in the number of adhered bacteria and reached to 73.71% with 20% TiO2 in PMMA. The effect of TiO2 nanoparticales on the K. pneumonia adherence appeared very clear and the reduction uis reached to 90.04% with 10% TiO2 in ABS.

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