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Article
Growth Assessment in Asthmatic Patients

Authors: Jinan Soaod Oraiby --- Haider Talib Hussain --- Asaad Abdullah Abbas --- Maher Mohammed Hassan
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2013 Volume: 12 Issue: 3 Pages: 376-382
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

BSTRACT: BACKGROUND:Asthma is a chronic disease &the chronic disease states regardless etiology can cause growth failure ininfant &toddler. OBJECTIVE :To assess growth of asthmatic patients PATIENT AND METHODS: One hundred asthmatic children between (5-15 years) of age . Both asthmatic & control group studied in term of height, weight & Skin fold thickness, all anthropometric measurements of height, weight &skinfold thickness measured for both groups.RESULT: Height, weight &skin fold thickness were significantly retarded in asthmatic, the more severe thedisease &longer duration the more retardation in the height & weight.The height was affected more than the weight by the disease duration & severity .The diminution in skinfold thickness was retarded both with increase disease duration & severity but the female was lessretarded than male as the disease duration prolonged.CONCLUSION: All growth parameter (height, weight, SFT) affected by asthma (duration & severity), so the growthparameters can be used in asthmatic children to evaluate the effect of treatment


Article
Evaluation of serum srace element levels in children with bronchial asthma
تقييم مستويات عنصر مصل الدم لدى الأطفال المصابين بالربو القصبي

Author: Parween Abdulsamad Ismahael
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2011 Volume: 15 Issue: 3 Pages: 50-55
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objectives: The metabolism of several trace elements has been reported to alter in bronchial asthma and these elements might have specific roles in the pathogenesis and progress of this disease. The aim of the present study was to investigate serum levels of Zinc, Copper, Calcium, Iron and Magnesium in asthmatic childrenPatients and Methods: The comparative study includes 56 asthmatic patients and 44 healthy non asthmatic control subjects. The trace elements concentrations were measured by means of an atomic absorption spectrophotometer, results were calculated from the calibration curve obtained by statistical analysis of concentration Vs Absorbance data for elements using fitting of straight line by least square.Results: Mean(±SD) zinc level was significantly (p<0.01) decreased in asthmatic children (70.6±8.3 μg /dL) compared with controls non asthmatic children (78.3± 9.2 μg /dL),calcium and iron serum concentrations were significantly(p<0.001) higher in asthmatic patient (10.98±2.53 mg/dL, (113.23 ± 45.47 μg/dl) respectively compared with controls (8.23±3.4mg/dL,83.25±29.43 μg /dL) respectively, on the other hand copper level was significantly (p<0.01) higher in asthmatic children (143±20.8μg/dl) in comparison to the control values (130±22.7 μg/dL). Magnesium concentration was significantly lower in comparison to the control values (p<0.01).Conclusion: The results support that deficiency of Mg, Zn, Cu, Ca and Fe may play a role in the development of asthma.


Article
Risk factors of bronchial asthma among adults in Basrah
العوامل المثيرة للربو القصبي بين البالغين في مدينة البصرة.

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Abstract

Objective: To study the risk factors aggravating bronchial asthmatic attacks among adult patients in BasrahMethods: Ninety six asthmatic patients, their ages ranged from 15 to 47 with a mean ages 29.66±7.37 years and a mean weight of 70.15 ± 12.74, were studied prospectively from January 2015to April 2016 from two consultation clinics. It was a paper questionnaire based study, the questions and answers were completed by the patients and sometimes with help of close relative, if necessary. Because of the increasing number of aggravating factors in modern life and the pollutions of community, the patients were classified into three groups according to number of triggering factors.Results: Atopic individual was more liable to multiple allergens in comparison to non-atopic individual with 95% CI (.051-0.424) and a value (0.010). The commonest risk factors that had been found aggravating attacks of bronchial asthma in the presence of history of atopy was upper respiratory tract infection with 95% CI ( 0.099-0.441), humidity(95%CI of 0.054-0.414), seasonal allergy (95%CI of 0.008-0.474), spicy food intake with 95% CI of 0.256-0.277, perfumes (odorous) with 95% CI 0f (0.197-0.568), Low corticosteroid medications with 95% CI OF (0.069-0.433) and dusty environments with 95% CI of (0.133-0.490). Asthma was more common at younger age group and older age group constitutes only 11.4%.Conclusion: In allergic individuals in Basrah, respiratory tract infection, humidity, seasonal changes, indoor perfumes, spicy food diet, low dose of cortico steroid, dusty environments, all are common association with asthma symptoms in atopic individual.

الهدف: دراسة عوامل الخطر المشتركة المشددة لنوبات الربو الشعب الهوائية بين المرضى الكبار في البصرة.العينة والطريقةِ: ستة وتسعون ممن يعانون من مرضى الربو القصبي من الفئة العمرية من 15 إلى 47 مع متوسط العمر 29.66 ± 7.37 سنة ومتوسط وزن الجسم للعينةِ هو 70.15 ± 12.74كيلو غرام ،وكانت الدراسة مستقبلية للفترة من كانون الثاني/ يناير 2015 إلى نيسان / أبريل عام 2016 في عيادتين استشاريتين في مدينة البصرة جنوبي العراق. وتمت الدراسة بتوزيع استبيان على أساس ورقة، ونوع من الأسئلة والأجوبة، وأكملت من قبل المريض وفي بعض الأحيان بمساعدة ذويه إن لزم الأمر. وبسبب العدد الكبير للعوامل المثيرة لنوبات الربو في الحياة الحديثة، والتلوث من المجتمع والتلوث في البيئةِ قمنا بتصنيف المرض إلى ثلاث مجموعات وفقا لعدد العوامل المثيرة لحدوث النوبة.النتائج: الأفراد المصابون بالحساسية أكثر عرضة للعوامل المثيرة للنوبة بالمقارنة بالأفراد الغير مصابين مع (.051-0.424) CI % 95 وقيمة (0.010) عوامل الخطر الأكثر شيوعاً التي قد تم العثور على تفاقم نوبات الربو القصبي.حلت عدوى الجهاز التنفسي العلوي مع 95%CI (0.099-0.441)،الرطوبة (CI 95% من 0.054 إلى 0.414)، الحساسية الموسمية (CI 95% من 0.008 إلى 0.474)، وتناول الطعام حار الموئل مع فاصل الثقة 95% من 0.256- إلى 0.277، الروائح والعطور ) مع 95%CI 0.197 إلى -0.568 (ومنخفضة أدوية الكورتيزون مع فاصل الثقة 95% من (0.069- إلى0.433) والبيئات المتربة مع فاصل الثقة 95% من (0.133-الى0.490). والربو أكثر شيوعاً في الفئة العمرية من الشباب وكبار السن من الفئة العمرية يشكل 11.4 في المائة فقط.الاستنتاج: عند الأفراد الذين يعانون من الحساسية ،عدوى الجهاز التنفسي، والرطوبة، والتغيرات الموسمية، الروائح والعطور، الوجبة الغذائية الغنية بالتوابل، تقليل جرعة الستيرويدات، البيئات الُمتربة، جميع هذه العوامل المشتركة مع أعراض الربو في الأفراد الذين يعانون من فرط الحساسية.


Article
Effect of Curcumin Supplement on Pulmonary Functions, Total and Differential White Blood Cell Count, Serum Level of Leptin and Body Mass Index in a Sample of Iraqi Patients with Chronic Bronchial Asthma
تأثير الكركم كمكمل غذائي على وظائف الرئة , العد الكامل والتفصيلي لكريات الدم البيض, مستوى اللبتين في مصل الدم و مؤشر كتلة الجسم في عينة من المرضى العراقيين المصابين بمرض الربو القصبي المزمن

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Abstract

Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation together with increased oxidative stress that lead to clinical symptoms of asthma.Obesity is a known risk factor of asthmaas the obesity is correlated with systemic inflammation and airway restriction. Curcumin, a natural product derived from the rhizomes of Curcuma longa (Turmeric), has a wide range of beneficial properties including anti-inflammatory and weight reducing agent. This study was designed to evaluate the effect of curcumin as supplement therapy on the pulmonary function, total and differential white blood cell count and metabolic status of chronic bronchial asthmatic patients. It is a prospective randomized controlled interventional study carried out on 40 patients visiting Al-Yarmouk teaching hospital and conducted from October 2017 to April 2018. The patients were allocated into group1; include 17 asthmatic patients assigned to receive conventional therapy for asthma alone, and group 2; include 23 asthmatic patients assigned to receive conventional therapy for asthma plus 750 mg curcumin capsule twice daily for two months. Results revealed significant improvement in forced expiratory volume in one second (FEV1) and the ratio of forced expiratory volume in one second to forced vital capacity (FEV1/FVC) in group 2 patients after two months(P<0.01). The total white blood cell count didn’t show any difference after treatment except decrease in neutrophil count after curcumin supplement (p< 0.05). The leptin level and body mass index present with no significant difference in both groups after two months (p >0.05).

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