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Article
Cardiovascular Manifestations of Primary Hypothyroidism

Authors: Ahmed Shaker Al-Zaidi --- Adil S .Abdul-Ghafour --- Abdulla J Minshed Al-Farttoosi
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2010 Volume: 9 Issue: 2 Pages: 113-119
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND:Primary hypothyroidism accounts for 90 to 95 %of all cases of hypothyroidism. Thyroid hormone deficiency increases systemic vascular resistance, decreases contractility and slow the heart rate .OBJECTIVE: To investigate cardiac changes in primary hypothyroidism.METHODS:In this prospective study 36 patients with untreated primary hypothyroidism were compared with 30 healthy persons. Cardiovascular evaluation of all subjects had been made both clinically and by the following studies :Chest X-Ray, electrocardiography, serum lipid and Echocardiography.RESULTS::The main cardiac manifestations of hypothyroidism were: Easy fatigability( 88.9 %(, exertional dyspnea )75%o),obesity or gaining weight( 66.7 %(, sinus bradycardia ) 47.2 %(and peripheral edema(11.1 %(Electrocardiography showed sinus bradycardia in( 47%( low QRS voltage in )33.3%( , flat or inverted T wave(27.8%), prolonged QT interval )19.5%), first degree heart block in( 19.5 %(.Echocardiography showed the following :a decrease in global systolic function, asymmetric sepalhypertrophy in )91.6%) Pericardial effusion in )38.8%).Low QRS voltage was found to be related to thyroxin level and age of the patient .No correlation was found between heart rate and thyroxin level.CONCLUSION:Primary hypothyroidism accompanied by significant changes in cardiovascular system which may explain the development of premature coronary artery disease in these patients.


Article
Cardiovasular Manifestations of Primary Hypothyroidism

Author: Sabah M. Zangana
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2015 Volume: 12 Issue: 2 Pages: 446-454
Publisher: Babylon University جامعة بابل

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Abstract

Hypothyroid patients are liable for cardiovascular complications, especially arrhythmias hypertension, ventricular dysfunction ischemic heart disease, and pericardial effusion. To detect the above-mentioned cardiovascular manifestations in hypothyroid patients before and after treatment. 92 cases of hypothyroidism, )Collected within 25 years) diagnosed by hormonal assay were studied for their cardiovascular manifestations, clinically, by ECG, chest X-ray, echocardiography and sometimes exercise ECG at time of diagnosis (from 1988-2002 ) and followed for the first 10 years from the starting point of the treatment.Among 92 hypothyroid patients studied, cardiovascular manifestations were not high before treatment, while after treatment and during the first 10 years of follow-up, no relevant cardiovascular disease could be detected.Although hypothyroid patients are liable for cardiovascular complications, in this study cardiovascular manifestations are not common in hypothyroid patients neither before nor after the treatment.

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