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The effects of chloroquine phosphate on the serum level of proinflammatory interleukins in patients with knee osteoarthritis.

Authors: Haider M.Jawad حيدر محمد جواد --- Sami Salman سامي سلمان --- Ali Kathum علي كاظم
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2011 Volume: 53 Issue: 1 Pages: 93-97
Publisher: Baghdad University جامعة بغداد

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Article
The role of Chloroquine phosphate on rheumatoid factor in patients with knee osteoarthritis

Authors: Mohammed H. Alosami --- Kismat M. Turki --- Eman S. Saleh
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2009 Volume: 51 Issue: 1 Pages: 60-61
Publisher: Baghdad University جامعة بغداد

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Background: Osteoarthritis (OA) is disorder of diarthrodial joints characterized clinically by pain and functional limitation. Rheumatoid factor (RF) represents one of routine laboratory tests that done for all patients have joint complaints. Chloroquine phosphate (CQP) is a disease modifying antirheumatic drug (DMARD) used for patients suffer from knee osteoarthritis (KOA) in order to reduce their RF value and improves the disease status. Objective: To evaluate the effect of chloroquine phosphate on rheumatoid factor (RF) level in serum of patients with knee osteoarthritis KOA) Design: case report.Subjects and methods: RF value were assessed quantitatively by ELISA technique before and after treatmtnt for a total of fifty five patients with KOA (30 femal and 25 male) their age ranged from (50-66 years) selected randomly from out patient clinic in Baghdad Teaching Hospital , Medical City Baghdad; suffering from KOA. All patients were treated with oral dosage form of CQP for one month twice daily.Results: Mean serum RF level was significantly reduced (p<0.05) in serum of patients after treatment with CQP for one month.Conclusion:CQP is a disease modifying antirheumatic drug (DMARD) used for patients suffering from KOA in order to reduce their RF value and improves the disease status.


Article
Role of Chloroquine phosphate on Acute phase reactant in patients with knee osteoarthritis

Author: Kismat M. Turki* , Ph.D قسمة محمد تركي
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2008 Volume: 50 Issue: 3 Pages: 400-402
Publisher: Baghdad University جامعة بغداد

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