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Article
Preoperative and Postoperative Serum Immunoglobulins

Author: Batool H. Al-Ghurabi*;Ph.D بتول الغرابي
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2007 Volume: 49 Issue: 2 Pages: 189-192
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Quantitation of serum immunoglobulins (IgG, IgA and IgM) provides useful information for the evaluation of certain cancers.Objectives:to estimate serum immunoglobulins level before and after surgery, and to shed light on the correlation of immunoglobulins with progression of CRC.Patients and Methodes. By single radial immune diffusion method IgG, IgA, IgM were estimated in 100 CRC patients preoperatively, and in 20 patients postoperatively compared with 35 patients control with ulcerative colitis (UC) and 50 healthy control.Results: The study showed significantly increased the serum IgM level in patients group preoperatively (p<0.001) compared with control group. On the other hand, no significant differences were observed in respect to the mean of IgG, IgA, and IgM after surgical excision of the tumor in 20 patients.Conclusion: These finding suggests that high level of IgM might be considered as prognostic indicator.Keywords: serum immunoglobulins, Colorectalcancer cases


Article
Physical Problems of Patients after Colorectal Cancer in Mosul Governorate
المشاكل الجسمية للمرضى المصابين بسرطان القولون والمستقيم في محافظة الموصل

Authors: Ghalib A. Khalaf --- Narmeen B. Tawfiq
Journal: kufa Journal for Nursing sciences مجلة الكوفة لعلوم التمريض ISSN: 22234055 Year: 2013 Volume: 3 Issue: 1 Pages: 23-31
Publisher: University of Kufa جامعة الكوفة

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Abstract

Objective: Assessment the quality of life concerning physical problems for patient after colorectal cancer in Mosul Governorate.Methodology A descriptive cross-sectional design is employed through the present study from 1st June 2011 to 15th December 2011 in order to assess the quality of life concerning physical problems for patient after colorectal cancer in Mosul Governorate.A purposive (non probability) sample is selected for the study which includes (60) patients diagnosed with colorectal cancer were treated in Mosul Oncology and Nuclear Medicine hospital or the patients who visited the outpatient clinic in the same hospital for medical follow–up and further treatment. Data were gathered through the patients` interviewed. Assessment questionnaire consist of two parts contains demographic characteristic, the other part concerning of quality of life concerning physical problems after colorectal cancer. Reliability and validity of this tool is determined through application of a pilot study and panel of experts. Data were analyzed through the application of descriptive statistical (frequencies and percentages) and inferential statistical (mean of score).Content validity of the instrument was done through eliciting the opinions of a panel of (13) experts and reliability through a pilot study by using Internal consistency reliability is determined through the computation of the cronbach alpha correlation coefficient of the scale on data gathered from patients.Results: The Overall results revealed that the quality of life related to physical problems for patients after colorectal cancer were acceptable. So, there is no significant correlation between the quality of life related to physical problems for these patients and some demographic characteristics such as gender, age, marital status and education level.The study concludes that colorectal cancer are most common in married than in unmarried, half patients age are between 40 and 60 years old, have a relatively low level of education, many are unemployed and they reside in the urban areas in Mosul. Recommendations: The study recommended to preparation of an educational program for patients with colorectal cancer and to raise awareness and education among families of patients to provide a better life for their patients.

الهدف: تقييم نوعية الحياة ذات العلاقة بالمشاكل الجسدية للمرضى بعد سرطان القولون والمستقيم في محافظة الموصل. المنهجية: دراسة وصفية طبقية استعمل فيها أسلوب التقييم تم استخدامه في الدراسة الحالية للفترة من 1 حزيران 2011 إلى 15 كانون الاول 2011 من تقييم نوعية الحياة ذات العلاقة بالمشاكل الجسدية للمرضى بعد سرطان القولون والمستقيم في محافظة الموصل. اختيرت عينة عمديه قصديه (غير احتمالية) في الدراسة وقد تكونت من (60) مريض في مستشفى الاورام والطب الذري في الموصل وكذلك المرضى الذين زاروا العيادة الخارجية في المستشفى نفسه للمتابعة الطبية وإكمال العلاج. تم جمع بيانات الدراسة عن طريق مقابلة المرضى الراقدين والمراجعين في المستشفى المذكور. تكونت استمارة التقويم من جزئين شملت المعلومات الديموغرافية والسريرية المرضى والجزء الأخر تعلق بنوعية الحياة ذات العلاقة بالمشاكل الجسدية بعد سرطان القولون والمستقيم. تم إجراء المصداقية والثبات لأداة التقييم من خلال الدراسة الاستطلاعية وعرض الأداة على مجموعة من الخبراء. تم تحليل البيانات من خلال أسلوب الإحصاء الوصفي( التكرار والنسب المئوية) والإحصاء ألاستنتاجي(المتوسط الحسابي).تم تحديد ثباتية استمارة الاستبانة من خلال اجراء دراسة مصغرة باستخدام الاتساق الداخلي ومن خلال حساب معامل الارتباط كرونباخ ألفا على البيانات التي تم جمعها من المرضى وحددت مصداقيتها من خلال الحصول على آراء لجنة مكونة من (13) خبيرا. وقد تم تحليل البيانات من خلال تطبيق التحليل الإحصائي الوصفي (النسب المئوية) والتحليل الإحصائي الاستدلالي (متوسط النقاط).النتائج: وبشكل عام كشفت النتائج ان نوعية الحياة ذات العلاقة بالمشاكل الجسدية للمرضى بعد سرطان القولون والمستقيم كانت مقبولة، وليس هناك علاقة معنوية بين نوعية الحياة لهؤلاء المرضى وبعض الخصائص الديموغرافية مثل الجنس والعمر والحالة الزوجية ومستوى التعليم.واستنتجت الدراسة أن الاصابة بسرطان القولون والمستقيم هي أكثر شيوعا بين المتزوجين عن اولئك الغير متزوجين، كذلك كانت اعمار نصف المرضى ما بين 40 و 60 سنة، وكان لديهم مستوى متدني من التعليم، والعديد منهم عاطلين عن العمل ويقيمون في المناطق الحضرية في الموصل. التوصيات: أوصت الدراسة بإعداد برنامج تثقيفي للمرضى المصابين بسرطان القولون والمستقيم وزيادة الوعي والتثقيف بين عوائل المرضى لتوفير حياة افضل لمرضاهم.


Article
The expression of CD44 in colorectal cancer and association with clinicopathological features

Authors: Dina W. Abd --- Sura D.Dawood --- Wasan A. Bakir Ikram A. Hassan
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2014 Volume: 13 Issue: 1 Pages: 54-58
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Background: Cluster of differentiation number 44 (CD 44) is a family of cell-surface adhesion molecules which exist in several isoforms arising from mRNA alternative and encoded by using gene located at chromosome 11 on the short arm p13. The CD44 gene is composed of 10 constitutively spliced exons and 10 variable exons, residing between constitutive exons 5 and 6.In colorectal carcinoma, the relationship between the expression of variant exons and tumor progression is controversial. Some studies have suggested that the expression of certain variant exons resulted in increased tumor progression, while other has no correlation. Objectives: Investigate CD44 immunoreactivity in colorectal carcinoma and determine the association with clinicopathological features. Material and methods: Paraffin- embedded tumor specimens from (70) patients with colorectal adenocarcinoma and (70) healthy control were assessed by immunohistochemisrty for the expression of CD44. Result: Statistical analysis of CD44 expression revealed highly significant difference in colorectal carcinoma patients than in control group. Also there were a relationship between CD44 expression and range of clinicopathological features. Conclusion: CD44 is robust marker for colorectal carcinoma.

Keywords

CD44 --- colorectal cancer


Article
Comparison of Colorectal Cancer in Patients Below and above 40 Years
سرطان المستقيم والقولون مقارنة بين الاعمار تحت وفوق سن الاربعين

Authors: Hala Ibrahim Salih هاله ابراهيم --- Arkan. Abdulrahman.M Al-Ogaili اركان العقيلي --- Abdulhameed J.Ali عبد الحميد جمعه
Journal: IRAQI JOURNALOF COMMUNITY MEDICINE المجلة العراقية لطب المجتمع ISSN: 16845382 Year: 2017 Volume: 30 Issue: 1 Pages: 38-43
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Background: Colorectal cancer is a common disease in old patients, but it has become increasingly evident in young patients.Objective: To compare the colorectal carcinoma, between young and old patients.Patients and Methods: a prospective study of 87 patients with colorectal cancer treated in the department of surgery at Al-Yarmouk Teaching Hospital, From Jan.2007-Jan.2012. The patients were divided according to age into group A; below 40years, and group B; above 40years. These two groups were compared regarding; clinical presentations, pathological features of the tumor, staging of the tumor, and sex.Results: Twenty three patients (26.44%) in group A; their age ranging from 12 to 40 years, with male to female ratio was 1.3:1 the commonest affected age group was 31-40 years old, positive family history was significantly higher than that in group B (39%), the commonest presenting features were altered bowel habits (87%) and abdominal pain (65%), left side colonic tumors were more common than right side tumors, Moderately differentiated tumors were constitute 52% and60.8% were stage C2, there was no significant difference between the two groups.Conclusion: there was an increasing incidence of colorectal cancer in young patients. Family history was a risk factor for group A patients. Diagnosis was usually delayed and this needs more attention because of the lack of alarming symptoms


Article
METABOLIC SYNDROME AND COLORECTAL CANCER IN DUHOK, KURDISTAN IRAQ
متلازمة الايض وسرطان القولون والمستقيم في دهولك، كوردستان - العراق

Authors: INTISAR SALIM PITY أنتصار سالم بتي --- DHIA JAAFAR AL-TIMIMI ضياء جعفر التميمي --- SHERWAN FERMAN SALIH شيروان فرمان صالح
Journal: Duhok Medical Journal مجلة دهوك الطبية ISSN: ISSN: 20717334 (online)/ ISSN: 20717326 (Print) Year: 2016 Volume: 10 Issue: 2 Pages: 10-20
Publisher: University of Dohuk جامعة دهوك

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Background: Increasing evidence arguing the association between metabolic syndrome andcolorectal cancer in general population is in progress. Since there is a lack of information aboutthis issue in Duhok population, the present study was conducted to investigate the associationbetween metabolic syndrome and its components in patients with colorectal cancer.Methods: A case control study was conducted on 158 subjects, 79 patients with histologicallydiagnosed colorectal cancer and 79 apparently healthy subjects. Demographic information wascollected for all subjects through an interview. Components of metabolic syndrome includingabdominal waist circumference (WC), blood pressure (BP), fasting serum glucose (FSG),triglyceride (TG) and high density lipoprotein-cholesterol (HDL-ch) were measured.Results: Of the seventy nine patients with colorectal cancer, 23 (29.1%) had metabolicsyndrome as compared to 20 (25.3%) of the healthy subjects, with rates of 20.2% and 7.6% formales and 8.9% and 17.7% for females, respectively. Patiexhibited a significantly higher prevalence of metabolic syndrome than did the healthy subjects(odds ratio= 2.08, p= 0.024).Conclusion: Patients with colorectal cancer may be associated with increased risk of metabolicsyndrome in a Duhok population, particularly among males and older age group.

الهدف: هناك زيادة في الأدلة حول العلاقة بين متلازمة الأيض وسرطان القولون والمستقيم في عموم السكان، وبسبب نقص المعلومات حول هذه المشكلة لدى سكان دهوك أجريت هذه الدراسة بهدف تحليل العلاقة بين متلازمة الأيض ومكوناته لدى المرضى الذين يعانون من سرطان القولون والمستقيم.طرق البحث: أجريت الدراسة من نمط الحالات والشواهد على 158 شخص، 79 منهم مريض بسرطان القولون والمستقيم تم تشخيصهم بالفحص النسيجي و79 أشخاص أصحاء. تم جمع المعلومات السكانية لجميعهم من خلال المقابلة المباشرة مع قياس مكونات متلازمة الأيض بما في ذلك محيط الخصر، ضغط الدم، نسبة غلوكوز الدم، الشحوم الثلاثية والكوليسترول من نوع البروتين الدهني العالي الكثافة.النتائج: من مجموع التسعة وسبعين مريض بسرطان القولون والمستقيم، 23 (29.1٪) منهم كانت لديهم متلازمة الأيض بالمقارنة مع 20 (25.3٪) من الأصحاء، مع معدلات 20.2٪ و7.6٪ للذكور و8.9٪ و 17.7٪ للإناث، على التوالي. تبين بأن المرضى من الفئة العمرية ستون سنة فأكثر يعانون من متلازمة الأيض بمعدلات أعلى بكثير من الأصحاء (نسبة الأرجحية = 2.08، P = 0.024).الاستنتاج: قد تكون زيادة خطر الإصابة بمتلازمة الأيض مرتبطة بمرضى سرطان القولون والمستقيم لدى سكان محافظة دهوك، وخاصة بين الذكور وكبار السن.


Article
Proportion of Colorectal Cancer Proved by a Histopathological Study on Patients Who Underwent Colonoscopy

Author: Nadir A. Sanad Al‑Jenabi, Ali Abaid Kadhem, Hamid Fadhel Abbas
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2019 Volume: 16 Issue: 2 Pages: 141-144
Publisher: Babylon University جامعة بابل

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Background: Colorectal cancer is the third most common cancer in the world, and the general lifetime risk of development cancer in the UnitedStates is 6%. Many people with colon cancer experience no symptoms in the early stage of the disease. When symptoms appear, they will likelyvary, depending on the cancer size and location in the large intestine. Objective: The objective of this study was to determine the proportion ofcolorectal cancer proved by a histopathological findings on patients who underwent colonoscopy and also to study the association of colorectalcancer with age, gender, and presenting signs. Materials and Methods: This study has been carried out at gastroenterology, and colonoscopyhas been done for 366 patients with signs and symptoms of lower gastrointestinal tract infection. Out of those patients, biopsies have beentaken from 320 patients. Results: Results of distribution of the patients who underwent colonoscopy by presenting signs and symptoms foundthat the majority (80.6%) of the patients presented with bleeding per rectum. The distribution of (320) patients by histopathological findingsfound that only 17.8% of patients had colorectal tumors. Conclusion: Younger age group is more involved in colon cancer and left colon wasthe most common site, and when symptoms occur, the tumor is locally invasive.


Article
Oxidative Stress and Antioxidant Status inColorectal Cancer and Healthy Subject
الاكسدة الاجهادية ومضادات الاكسدة الانزيمية عند المرضى المصابينبسرطان القولون وعند الأشخاص الإصحاء

Author: Noah A. Mahmood نوح عبد القادر محمود
Journal: Iraqi Journal of Cancer and Medical Genetics المجلة العراقية للسرطان والوراثة الطبية ISSN: 20786123 Year: 2010 Volume: 3 Issue: 1 Pages: 1-6
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Background: Total antioxidant status(TAO), superoxide dismutase (SOD) and Catalase (CAT) areantioxidant defensive enzymes that are catalyze the reduction of reactive oxygen species (ROS) to nonharmful substance. Aim: The study focuses on the serum super oxide dismutase enzyme level, CAT level andtotal antioxidant status in colorectal cancer patients, which result due to an imbalance between aggressiveand defensive factors. Materials and Methods: the study included 40 patients and 20 healthy individuals forcomparative analysis were considered for the present study. (TAO), serum (SOD) and (CAT) levels of eachindividual were performed. Results: Statistical analysis of serum antioxidant enzymes level and antioxidantstatus revealed a significant increase in SOD, CAT of patients group (p.≥0.05), and (P.≥0.01) respectively.The TAO was significant increase (p.≥0.001). The increasing preponderance of serum SOD, CAT levelsand the TAO can be explained on the basis of alteration on enzymes activity, which may lead to disturbancein homeostasis of antioxidant/oxidant balance... Conclusions: TAO, Catalase and Superoxide dismutaseenzyme used a biomarker of enzymatic alteration in different diseases including cancer.

قيست مضادات الاكسده الكليه وانزيمي الكاتليز والسوبر اوكسايد دسميوتيز والذين يرتبطون بصوره اساسيه مع زياده الاكسده الاجهاديه والناتجه من زياده جذور الاوكسجين الحره.حيث تم قياس مستويات الانزيمات في مصول المرضى المصابين بسرطان القولون والمستقيم وعند مقارنتها مع الاشخاص الاصحاء حيث تم قياس مستويات الانزيمات عند 40 مريضا مصابا بسرطان القولون والمستقيم و20 مصلا من اشخاص اصحاء.
وجد ان مستوى انزيم السوبر اوكسايد دسميوتيز وانزيم الكاتليز قد ارتفع بشكل ملحوظ بالمقارنه مع الاشخاص الاصحاء.وبينت الدراسه ان مستوى مضادات الاكسده الكليه قد ارتفعت ايضا وبشكل ملحوظ عند المرضى المصابين بالسرطان وعند الاشخاص الاصحاء.
بينت الدراسه ان زياده نسبه الانزيمات عند المرضى بالمقارنه مع الاشخاص الاصحاء ناتحه عن تاثر الانزيمات الموكسده بالنسب العاليه للجذور الحره والتي توثر على الموازنه بين المواد الموكسده والانزيمات المضاده للاكسده.


Article
Colorectal cancer in a group of Iraqi patients

Author: Sabeha Moosa Al‐Bayati
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2009 Volume: 8 Issue: 1 Pages: 36-39
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Background Colorectal cancer is the second most common internal malignancy and the second leading cause of cancer death (after lung cancer).The condition becomes increasingly common after the age of 50.Because it is a common problem in certain areas of the world and because its insidious nature of onset that sometimes is too late when diagnosed, keeping high index of suspicion with developing screening tests that are reliable and easily performed are vital in diagnosis. Objective: To highlight some of the demographic, laboratory, and histopathological criteria of colorectal cancer in a group of Iraqi patients. Methods This study is a descriptive cross sectional study that had enrolled 30 patients with colorectal cancer. The patients included in this study had been selected from those patients who had attended the endoscopic unit / department of medicine at Al-Yarmouk teaching hospital during the period between the 1st of September 2006 to the 1st of September 2007. Patients diagnosed to have colorectal cancer by colonoscopy, and biopsy samples were taken for histopathological study, and blood samples were taken for carcinoembryonic antigen. Results This study revealed that 80% of the patients were older than 50 years of age with a male: female ratio of 2.75:1.63.33% of the patients were smokers. The study revealed that the presentation of the disease is usually insidious with abdominal pain, change in bowel habit and haematochezia and melena seen in 83.34% of the patients. 66.67% of the tumors were located in the rectosigmoid.All the tumors were adenocarcinoma. Carcinoembryonic antigen was +ve in 60% of the patients. Conclusion Colorectal cancer is more common in old male patients with smoking habit.


Article
Assessment of serum carcinoembryonic antigen in colorectal cancer patients treated by surgery and chemotherapy

Author: Shahbaa A. Al-Bayati شهباء البياتي
Journal: Iraqi Journal of Pharmacy المجلة العراقية للصيدلة ISSN: 16802594 Year: 2011 Volume: 11 Issue: 2 Pages: 12-16
Publisher: Mosul University جامعة الموصل

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Objective: Carcinoembryonic antigen (CEA) is a protein found in many types of cellsassociated with tumors and the developing fetus. The main use of CEA is as a tumormarker, especially with intestinal cancer. This study was designed to evaluate theeffect of surgery and chemotherapy on the level of CEA.Patients and methods: The study was carried out in Al-Jamhoory Teaching Hospitalin Mosul from January to July 2010. Thirty patients with colorectal carcinoma weretreated by surgical removal of the cancer and chemotherapy. Blood samples weretaken from the patients one week before surgery and other blood samples were takenone week after surgery. Third blood samples were taken after one week of the firstcycle of chemotherapy. Serum carcinoembryonic antigen, ALP (alkalinephosphatase), ALT (alanine aminotransferase), total serum bilirubin (TSB), andalbumin were estimated from the samples.Results: After surgery serum CEA and WBCs were decreased significantly (P <0.001). Serum ALP was also decreased significantly (P < 0.05), while serum ALT,TSB, and albumin were not changed significantly after surgery compared with theresults before surgery. After chemotherapy, serum CEA and WBCs decreasedsignificantly (P < 0.001) compared with the results after surgery. At the same time,serum ALP, ALT, TSB, and albumin did not change significantly after chemotherapy.Conclusion: Surgical removal of tumor decreased CEA level, but it did notnormalize. Serum CEA can be used as a marker for the effectiveness of thechemotherapy on colorectal cancer.

هدف الدراسة: إن المستضد السرطاني الجنيني هو بروتين موجود في أنواع عديدة من الخلايا المرتبطة بالسرطان وفي الجنين في طور النمو. إن الاستعمال الرئيسي للمستضد السرطاني الجنيني كمعلم للسرطان وخاصة المرتبط بسرطان الأمعاء. تهدف هذه الدراسة لتقييم تأثير جراحة استئصال السرطان وكذلك تأثير العلاج الكيميائي على مستوى المستضد السرطاني الجنيني. المرضى وطرائق العمل: أجريت هذه الدراسة في المستشفى الجمهوري التعليمي في الموصل للفترة من كانون الثاني ولغاية تموز 2010. تم علاج ثلاثون مريضا مصابا بسرطان القولون بالجراحة لإزالة السرطان ومن ثم استعمال العلاج الكيميائي. أخذت عينات الدم من المرضى قبل العملية الجراحية بأسبوع وعينة أخرى بعد العملية الجراحية بأسبوع وعينة ثالثة بعد اسبوع من الجرعة الأولى من العلاج الكيميائي. وقد تم قياس مصل دم مستضد السرطان الجنيني والفوسفاتيز القاعدي و الالنين امينوترانسفيريز والبليروبين والالبومين.النتائج: كان هناك نقص معنوي (0,001 ب) في مصل دم مستضد السرطاني الجنيني وكريات الدم البيض وكذلك في مصل دم الوسفاتيز القاعدي ( 0,05 ب) في المرضى بعد العملية الجراحية مقارنة في المرضى قبل العملية, بينما لم يتغير مصل دم الالنين امينوترانسفيريز والبليروبين والالبومين. وبعد العلاج الكيمياوي كان مصل دم المستضد السرطاني الجنيني وكريات الدم البيض اقل معنويا (0.001  ب) من قبل العلاج الكيمياوي. في نفس الوقت لم يتغير معنويا مصل دم الفوسفاتي القاعدي والالنين امينوترانسفيريز و البليروبين والالبومين مقارنة بهذه القياسات بعد الجراحة.الاستنتاج: ان إزالة السرطان جراحيا قلل من مصل دم المستضد السرطاني الجنيني ولكنه لم يرجع إلى الحالة الطبيعية . من الممكن اعتماد المستضد السرطاني الجنيني كمعلم لمستوى تأثير العلاج الكيمياوي لسرطان القولون.


Article
Colorectal cancer in a group of Iraqi patients

Authors: Sabeha Moosa Al-Bayati --- Farkad Jasim
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2008 Volume: 7 Issue: 2 Pages: 36-39
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Background: Colorectal cancer is the second most common internal malignancy and the second leading cause of cancer death (after lung cancer).The condition becomes increasingly common after the age of 50.Because it is a common problem in certain areas of the world and because its insidious nature of onset that sometimes is too late when diagnosed , keeping high index of suspicion with developing screening tests that are reliable and easily performed are vital in diagnosis.Objective: To highlight some of the demographic, laboratory, and histopathological criteria of colorectal cancer in a group of Iraqi patients.Methods: This study is a descriptive cross sectional study that had enrolled 30 patients with colorectal cancer. The patients included in this study had been selected from those patients who had attended the endoscopic unit / department of medicine at Al-Yarmouk teaching hospital during the period between the 1st of September 2006 to the 1st of September 2007. Patients diagnosed to have colorectal cancer by colonoscopy, and biopsy samples were taken for histopathological study, and blood samples were taken for carcinoembryonic antigen.Results: This study revealed that 80% of the patients were older than 50 years of age with a male: female ratio of 2.75:1.63.33% of the patients were smokers. The study revealed that the presentation of the disease is usually insidious with abdominal pain, change in bowel habit and haematochezia and melena seen in 83.34% of the patients. 66.67% of the tumors were located in the rectosigmoid.All the tumors were adenocarcinoma. Carcinoembryonic antigen was +ve in 60% of the patients.Conclusion: Colorectal cancer is more common in old male patients with smoking habit.

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