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Article
The value of fine needle aspiration cytology in the diagnosis of oral and jaw lesions in patients with plasma cell dyscrasias

Author: Bashar H. Abdullah بشار عبد الله
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2005 Volume: 17 Issue: 2 Pages: 41-44
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Fine needle aspiration cytology (FNAC) has been found to be very useful for the diagnosis of lesions as multiple myeloma (MM) and plasmacytomas in different parts of the body. The usefulness of such procedure has not yet been verified in the oral and maxillofacial region. This study was conducted to verify the value of FNAC in the diagnosis of oral and maxillofacial lesions in patients with plasma cell dyscrasias.Patients and methods: After clinical and radiological examination, FNAC was done by the use of 10 cc syringes with 22-23 gauge needles on 11 patients with lesions affecting the maxillofacial region. The smears stained with Leishman’s stain, to be examined microscopically.Results: Twenty eight patients were examined throughout 1.5 years period, 11 had soft tissue/or bone lesions affecting the maxillofacial region. 9 patients with MM and 2 had plasmacytoma. Of 9 patients with MM, the mandible was involved in 5 patients, 3 lesions affected the maxilla, and while in one patient the maxilla and mandible were both affected. Soft tissue lesions were seen in 6 patients. The results of FNAC showed that all lesions were due to involvement with myeloma cell infiltrates, with one exception of 2 osteolytic lesions which were due to odontogenic infection.Conclusion: FNAC is a very useful and safe procedure to diagnose different types of lesions affecting the oral cavity in patients with plasma cell dyscriasis


Article
The Predictive Value of Fine Needle Aspiration Cytology in the Assessment of Cervical Lymphadenopathy

Author: Hayder M. Abdulnabi
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2007 Volume: 6 Issue: 3 Pages: 190-193
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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ABSTRACT :BACKGROUND:Cervical lymphadenopathy is a common clinical problem that needs a prompt diagnosis to manage. FNAC plays an increasing role in the differentiation of its pathology. The aim of this study was to show the value of cytological examination in the assessment of cervical lymphadenopathy in relation to histopathological examination.METHODS :A prospective study where 50 randomly selected patients with cervical lymphadenopathy underwent fine needle aspiration cytology in the pathological department, college of medicine, Kufa university, for the period from Feb.2004 to Feb.2005.RESULTS :Non specific lymphadenitis was the common pathology in 20 patients (40%), followed by tuberculous lymphadenitis in 16 patients (32%), lymphoma in 22% and metastatic tumour in 12% of cases respectively.In 44 patients out of 50 the the pathology was confirmed histopathologically.CONCLUSION :It is proved by this study that FNAC play an important role in the diagnosis of cervical lymphadenopathy as accurate as histopathological examination.


Article
IS FINE NEEDEL ASPIRATION CYTOLOGY A VALID DIAGNOSTIC TOOL IN NODULAR GOITER?
هل الرشف الابري الدقيق اداة تشخيصية صحيحة لانسجة عقد الغدة الدرقية؟

Authors: MOWAFAQ M. BAHADIN موفق بهاء الدين النقشبندي --- HAYDER HUSSEIN IBRAHIM حيدر حسين ابراهيم
Journal: Duhok Medical Journal مجلة دهوك الطبية ISSN: ISSN: 20717334 (online)/ ISSN: 20717326 (Print) Year: 2016 Volume: 10 Issue: 1 Pages: 90-98
Publisher: University of Dohuk جامعة دهوك

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Abstract

Background: Fine needle aspiration cytology (FNAC) is commonly used tests for diagnosis of thyroid nodules. Is available procedure and provides specific diagnosis rapidly with minimal complications. Aim: To assess the validity of FNAC in the evaluation of thyroid nodules performed at our institution and to compare our results with other studies elsewhere.Patients and methods: This study was conducted on 51 consecutive patients who underwent FNAC for diagnosis during the period from Feb 2012 -- Feb 2015. The final histopathological diagnosis was considered the gold standard. Results: The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of FNAC for the diagnosis of neoplastic thyroid nodules were 84.6%, 97.3%, 94.1%, 91.6%, 94.8% respectively. Papillary carcinoma was the common type in neoplastic group (53.8%).Conclusion: Our study suggests that FNAC is a sensitive, specific and accurate initial diagnostic test for the preoperative evaluation of patients with thyroid nodules. Our results are comparable with current published articles and the clinician should be encouraged to use FNAC as the initial modality in assessment of thyroid nodules.

الهدف : تقييم ‌دورالتشخیص بواسطة‌ الرشف الابري الدقیق لأنسجه‌ عقد الغدة‌ الدرقية‌ ومقارنتها مع نتائج الفحص النسیجی للغده‌ بعد إجراء العملية‌ الجراحية.الطريقة‌ : هذه‌ الدراسة‌ شملت 51 حاله‌ مرضیه ( 44 من الاناث و 7 من الذكور) یعانون من عقد الغدة‌ الدرقية‌ خلال الفترة‌ من شباط 2012 لغاية‌ شباط 2015 . لكل مریض تم اخذ عینه‌ الرشف الابري علی شرائح زجاجیه‌ ومعالجتها بماده‌ الهیماتوكسلین والایوسین ودراسة‌ النتائج ومقارنتها بالزرع النسیجی لنفس المریض .النتائج : اظهرت الدراسة‌ ان الرشف الابري الدقیق ذو فاعلية كبيرة في تشخيص الاورام الخبيثة للغدة الدرقية وكانت نسبه‌ حساسية‌ الفحص 84.6% وخصوصية‌ فی التشخيص 97.3 % والدقة‌ التشخيصية‌ 94.1% الاستنتاج : اعتمادا علی نتائج هذه‌ الدراسة‌ تبین أن فحص الرشف الابري الدقیق لعقد‌ الغدة‌ الدرقية‌ هو حساس ومتخصص وذا دقه‌ تشخیصیه‌ عالیه‌ فی حالات أورام الغدة‌ الدرقية االسرطانية‌ ومقاربة لدراسات اخرى مماثلة ومن المفضل استخدامها لتقييم حالات عقد الغدة الدرقية .


Article
IMMUNOCYTOCHEMICAL STUDY OF SMOOTH MUSCLE ACTIN (SMA) IN FINE NEEDLE ASPIRATION CYTOLOGY (FNAC) OF BENIGN AND MALIGNANT BREAST TUMORS

Author: Methaq M Najem ميثاق معين نجم
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2012 Volume: 10 Issue: 1 Pages: 87-92
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

BackgroundMyoepithelial cells play an important role in the interpretation of breast fine needle aspiration cytology, since these cells are believed to be a component of the benign process in the breast lesion. Myoepithelial cells distinction may be difficult occasionally, so their demonstration by immunocytochemistry method through myoepithelial cell marker like smooth muscle actin is a useful diagnostic tool to differentiate between benign and invasive malignant lesions.ObjectiveTo study the role of smooth muscle actin as immunocytochemical marker in the demonstration of myoepithelial cell as an aid in the diagnosis of benign breast lesions in fine needle aspiration cytolog of breast.MethodsForty five cases of fine needle aspiration cytology of palpable female breast lesions were selected. 25 out of these 45 cases comprised 20 invasive breast carcinoma and 5 fibrocystic diseases with atypia stained with smooth muscle actin by immunocytochemistry method directly and 20 cases comprised of 10 fibroadenoma and 10 fibrocystic disease stained with smooth muscle actin after destaining from H&E stain. All of these cases had a confirmatory histological diagnosis. ResultsSmooth muscle actin staining consistently highlighted the myoepithelial cells in smears of all histologically proven benign lesions such as fibroadenomas and fibrocystic changes. In contrast, invasive breast cancers demonstrated absence of staining with smooth muscle actin that seen in benign breast lesions.ConclusionApplication of smooth muscle actin immunostaining in breast fine-needle aspirates is feasible and practical. The use of destained H&E smears provides an effective means to directly examine any atypical cluster of cells for the presence of MEC differentiation. The demonstration of presence or absence of MEC differentiation in atypical cases can provide sufficient evidence to decrease error in diagnosis (false positive) of breast fine-needle aspirates.KeywordsSmooth muscle actin, fine needle aspiration cytology, breast lesions


Article
fine needle aspiration cytology and ultrasonography in the management of solitary thyroid nodule

Authors: Safa M. Al-Obaidi صفاء مزهر العبيدي --- salah M.Tajer صلاح مهدي تاجر --- hassan A. ALnaffakh --- mohammed A. Jouda
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: PISSN: 00419419 / EISSN: 24108057 Year: 2009 Volume: 51 Issue: 2 Pages: 139-142
Publisher: Baghdad University جامعة بغداد


Article
Fine Needle Aspiration Cytology of Hepatocellular Carcinoma
علم الخلايا غرامة إبرة الطموح من سرطان الكبد

Author: Enas Abdulmajeed Rasheed إيناس عبد المجيد رشيد
Journal: The Medical Journal of Tikrit مجلة تكريت الطبية ISSN: 16831813 Year: 2011 Volume: 2 Issue: 172 Pages: 161-168
Publisher: Tikrit University جامعة تكريت

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Abstract

A prospective study of (13) patients, from both sex, with hepatocellular carcinoma was done in Salahuldeen government in Tikrit teaching hospital in period extent from Feb. 2006 to Aug. 2010. Patients divided into: 1-Those underwent FNAC for liver mass (5 patients) (38.5%), for diagnosis in addition to clinical and radiological evaluation with measurement of alfa-fetoprtein (AFP) level in the serum of them. 2-Those didn't undergo FNA and diagnosis made by clinical and radiological evaluation, and measurement of serum AFP level, in addition to excisional biopsy for liver mass. Follow up of patients for both groups made by 6-12and18 months by clinical and radiological evaluation for tumor seeding along needle tract, distant spread and median survival. It has been showed that tumor seeding along needle tract didn't encountered in this study. Distant spread included brain, bone, lung and abdominal wall no statistically differ in both group, and seen in three patients of those underwent FNA (60%),and five patients of those didn’t undergo FNAC (62.5%) (P=0.7). Median overall survival rate was 13 months(8-18 months) in FNA group and 12 months in non-FNA group (8-16). The cumulative 6, 12- and 18 months overall survival were 80%, 60% and 40% respectively for FNAC group and 75%, 50 and 37.5% respectively for non FNAC group. There was no statistically differences between two groups (P= 0.77).

وأجريت دراسة استطلاعية ل(13) مريضا، من كلا الجنسين، مع سرطان الكبد في الحكومة Salahuldeen في المستشفى التعليمي في تكريت مدى الفترة من فبراير 2006 إلى أغسطس 2010. المرضى تنقسم الى: 1-أولئك خضع FNAC لكتلة الكبد (5 مرضى) (38.5٪)، لتشخيص المرض، بالإضافة إلى السريرية والإشعاعية تقييم مع قياس ألفا، fetoprtein (اف ب) مستوى في مصل الدم منها. 2-أولئك لم يخضع FNA والتشخيص السريري الذي أدلى به والتقييم الإشعاعي، وقياس مستوى المصل لوكالة فرانس برس، بالإضافة إلى خزعة استئصالية للكتلة الكبد. متابعة المرضى لكلا الفريقين التي أدلى بها 6 أشهر من قبل 12and18 السريرية والإشعاعية تقييم للبذار ورم على طول المسالك الإبرة، وانتشار بعيدة ومتوسط ​​البقاء على قيد الحياة. ولقد اظهرت ان لم يكن مصادفة بذر ورم على طول إبرة الجهاز في هذه الدراسة. وشملت انتشار بعيد الدماغ والعظام والرئة وجدار البطن لا تختلف إحصائيا في كل مجموعة، وينظر في ثلاثة مرضى الذين خضعوا FNA (60٪)، وخمسة من المرضى الذين لم يخضعوا FNAC (62.5٪) (P = 0.7 ). وكان متوسط ​​معدل البقاء على قيد الحياة عموما 13 شهرا (8-18 شهرا) في مجموعة FNA و 12 شهرا في غير FNA للمجموعة (8-16). وكانت أشهر و 18 شهرا البقاء الإجمالي 80٪، 60٪ و 40٪ على التوالي للفريق FNAC و 75٪ و 50 و 37.5٪ على التوالي للفريق غير FNAC - التراكمي 6 و 12. لم يكن هناك أي اختلافات إحصائية بين المجموعتين (P = 0.77).


Article
Comparative Study Of Fine Needle Aspiration Cytology and Ultrasonography In The Management Of Solitary Thyroid Nodule

Authors: Safa Mezher AL-Obaidi --- Kussay M. Abbas Zwain --- Hassan H. Zaini
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2006 Volume: 5 Issue: 1 Pages: 68-73
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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ABSTRACT: BACKGROUND: The incidence of clinically apparent thyroid nodules in the general population is 4.5%.The overall incidence of malignancy in solitary thyroid nodule ranges between 10% to 15%. U/S and FNAC are used to differentiate benign and malignant nodules with high percentage of sensitivity and specifity. OBJECTIVES: 1. To evaluate the utility of FNAC in the preoperative diagnosis of solitary thyroid nodule. 2. To evaluate efficacy of FNAC and U/S in differentiation between benign and malignant nodule. METHODS: 130 euthyroid patients with solitary thyroid nodule attending the department of general surgery in the teaching hospital in Najaf province during the period from November 2001 to November 2003. After clinical assessment all our patient underwent FNAC for their thyroid nodule, and then subjected to the U/S examination. RESULTS: Out of these130 patients, the female to male ratio was 7:1, correlation of FNAC with HPE showed a sensitivity of 83.3% and specificity of 100%. CONCLUSION : Our study as compared to other studies else where showed that U/S and FNAC are very important diagnostic tools in investigation of clinically euthyroid solitary thyroid nodules. They will give optimal results and avoid unnecessary surgery in certain patients without missing any malignancy in others


Article
A Parathyroid Cyst; Often Neglected In The Differential Diagnosis Of Cystic Neck Swellings: A Case Report
كيس الغدة حول الدرقية, ألاحتمال ألمهمل في التشخيص التفريقي لأكياس العنق: تسجيل حالة

Authors: Mohammed Kamil Mohammed محمد كامل محمد --- Wisam Khalid وسام خالد --- Sajid Saad Mohammed ساجت سعد محمد
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2017 Volume: 16 Issue: 1 Pages: 29-33
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Parathyroid cysts are a rare cause of cystic swellings of the neck. They are usually non-functioning and predominate in middle age women. We report the case of an apparently healthy 17-year-old girl with a relatively large cystic left sided neck swelling of two years duration. Diagnosis of Parathyroid Cyst was obtained after surgical resection. The case history, intraoperative finding and pathology were presented, the pitfalls of diagnosis were highlighted and the condition was discussed with appropriate conclusions and recommendations.

تعتبر اكياس الغدة حول الدرقية نادرة وعادة ما تكون غير فعالة ويكثر حدوثها في النساء منتصف العمر. نسجل هنا حالة فتاة في السادسة عشرة من العمر وبصحة مقبولة وتشكوا من تورم كيسي كبير نسبيا في الجهة اليسرى من العنق. تم تشخيص الكيس حول الدرقي بعد التداخل الجراحي. تم تسليط الضوء على تاريخ الحالة المرضية ونتائج التداخل الجراحي والفحص النسيجي للكيس وكذلك تم الاشارة الى المطبات في التشخيص السريري مع مناقشة الحالة وذكر الاستنتاجات والتوصيات المناسبة.


Article
Diagnostic Value of Fine Needle Aspiration Cytology (FNAC) in Salivary Gland Tumors

Authors: Atheer Talib Jiboon --- Najwa Jamil AbdulRazzak --- Sabah Abdulaziz
Journal: Journal of Oral and Dental Research مجلة طب الفم والاسنان ISSN: 23106417 Year: 2017 Volume: 4 Issue: 2 Pages: 130-139
Publisher: Iraqi Association for Oral Research الجمعية العراقية لبحوث طب الفم

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Abstract

Introduction Salivary gland tumors represent the most complex and diverse group of tumors encountered in the head and neck region. The diagnosis of these tumors is challenging and the histological examination in the form of incisional biopsy is the standard preoperative diagnostic method, but for major salivary glands this technique harbors the potential for facial scar, facial nerve injury, development of fstula and tumor cells spillage. This is why it is restricted to the minor gland pathology It is restricted to the minor gland pathology. Fine-needle aspiration cytology (FNAC), on the other hand, does not have such complications and therefore it is more accepted and preferable as a preoperative diagnostic method. Aim Assessment of diagnostic value of fne needle aspiration cytology (FNAC) in salivary gland tumors. Patients and Methods Twenty patients were involved; FNAC was performed. The study was conducted in the Department of Oral and Maxillofacial Surgery in Alshaheed Ghazi Alhareery for Specialized Surgeries Hospital at Medical City_ Baghdad, in the period from November 2015 to November 2016. FNAC was performed as preoperative diagnostic toolResults There was no signifcant difference between benign and malignant salivary gland tumors in terms of patients’ age and gender. The majority of tumors were in the parotid and minor salivary glands in the palate respectively. The malignant tumors showed higher prevalence, Mucoepidermoid Carcinoma followed by Adenoid Cystic Carcinoma were the most common malignant tumors while Pleomorphic Adenoma was the most common benign tumor. The values of FNAC Accuracy, Sensitivity, Specifcity, Positive predictive value (PPV) and Negative predictive value (NPV) were: 85%, 84.62%, 85.71%, 91.7% and 75% respectively. Conclusions FNAC has a reasonable reliability in differentiating benign and malignant salivary gland tumors with accepted level of accuracy, sensitivity, specifcity, positive predictive value and negative predictive value. The high positive predictive value of FNAC in this study indicates the good reliability to confrm the malignancy.


Article
Feasibility of Fine Needle Aspiration Cytology in the Diagnosis of Breast Lumps
جدوى الفحص الخلوي بواسطة السحب الوخزي الدقيق في تشخيص أورام الثدي

Author: Ali M.Ali Ridha علي محمد علي رضا
Journal: kufa Journal for Nursing sciences مجلة الكوفة لعلوم التمريض ISSN: 22234055 Year: 2019 Volume: 9 Issue: 2 Pages: 1-8
Publisher: University of Kufa جامعة الكوفة

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Background: most patients with breast mass are anxious (to start with) regarding method of final diagnosis. If FNAC is done by dependable hands it proves to be the least invasive and may lead (if positive) to one stage surgery. Aim of the study: The study aimed principally to evaluate the feasibility and accuracy of Fine Needle Aspiration Cytology (FNAC) in the diagnosis of breast lumps by comparing the results with the histopathological diagnosis. Methodology: data were prospectively collected from 103 female patients within a period of 5 years (Feb.2009 to Jan.2014). All patients had palpable breast lumps for which initially aspiration cytology of the lump has been done followed by partial or total surgical lump excision for final histopathological diagnosis and to compare the results.Results: Of all FNAC specimens, 98 (95%) were adequate for cytological interpretation. Of those evaluated cytological, 62 (62.8%) were benign, 9 (9%) were suspicious for malignancy and 27 (27.5%) were malignant. Of the surgical histopathological specimens, 40 (40.8%) were malignant.Conclusion : The FNAC procedure is a rapid method, easy to perform, of little cost and easily accepted by the patients and it provides a high specificity and quite reasonable sensitivity rates that can be used for rapid diagnosis and screening.Recommendation: FNAC results are better interpreted in correlation with the clinical and imaging findings to allow better management for the patient and are better to be used with ultrasound guidance for better and adequate aspirates.

خلفية البحث: يكون معظم مرضى عقدة الثدي قلقين بداية من طريقة التشخيص النهائي لمرضمن فأذا تم اجراء السحب الوخزي بأيادي مضمونة فأنه سيكون الطريقة الاقل عنفا وعندما يكون موجبا قد يؤدي الى اجراء عملية جراحية ذات مرحلة واحدة. الهدف : ان الغرض من اجراء هذا البحث هو لتقييم جدوى ودقة الفحص الخلوي السحبي الوخزي فی تشخیص اورام الثدي وذلك عن طريق مقارنة النتائج مع الفحص النسیجی التشریحی المرضي.المنهجية : تم جمع عينات من 103 مريضة (بصورة مستقبلية) في فترة 5 سنوات من (شباط / 2009 الى كانون الثاني / 2014)، كان جميعهن يشكون من وجود ورم او عقدة الثدي . أجري للمرضى بدايةً السحب الوخزي الدقيق من تلك العقد او الاورام لغرض الفحص الخلوي ومن ثم تم ترتيب اجراء التداخل الجراحي لرفعها كلاً او جزءاً لغرض اعداد التشخيص النهائي عن طريق الفحص النسيجي التشريحي المرضي ومقارنة النتائج.النتائج : كان سحب 98 ( 95.2%) عينة وخزية من اصل العدد الكلي للمرضى صحيحاً وكافياً لأعطاء نتيجة وافية بالفحص الخلوي فكان نتيجة 62 عينة منها (62.8%) حميداً و 27 عينة ( 27.5%) اعطت نتيجة غير حميدة (سرطانية) بينما كانت نتيجة 9 عينات بأتجاه (الشك) السرطاني . بعد اجراء الفحص النسيجي التشريحي المرضي على عينات الاورام المستأصلة جراحياً، تم تثبيت 40 منها (40.8%) كعينات سرطانية اكيدة.الأستنتاج : أن الفحص الخلوي بواسطة السحب الوخزي الدقيق هو طريقة سريعة، سهلة التنفيذ، قليلة التكلفة وسهلة التقبل من قبل المريض وهو ذات نسبة خصوصية عالية وحساسية معقولة يمكنه من التشخيص والمسح السريع. التوصيات : ان النتائج الحاصلة من الفحص الخلوي عن طريق السحب الوخزي الدقيق من الافضل ان يتم تفسيرها (تقييمها) طبقا وبالتزامن مع المشاهدات السريرية والتصويرية (اشعة وسونار الثدي) للحصول على علاج افضل للمريض ومن المستحسن ان يجري وخز ورمة الثدي بمساعدة السونار للحصول بشكل افضل على مادة خلوبة كافية.

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