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Article
THE RELATION OF HYPOKALEMIA TO HYPERTENSIVE AND NON-HYPERTENSIVE ISCHEMIC STROKE

Authors: Haider A. Husain حيدر علي حسين --- Hasan A. Al-Hamadani حسن عزيز الحمداني --- Munther T. Hamzah منذر طاهر حمزة
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2014 Volume: 12 Issue: 2 Pages: 102-107
Publisher: Al-Nahrain University جامعة النهرين

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Background:Several clinical and laboratory observations are consistent with the hypothesis that hypokalemia might be a risk factor for the development of ischemic stroke in humans.Objectives:To evaluate the level of serum potassium in ischemic stroke patients and its relation to non-stroke patients and those with hypertension.Methods:Serum potassium was estimated from one hundred newly discovered first-life ischemic event of acute ischemic stroke patients and one hundred control patients with an attempt to evaluate the its level in ischemic stroke and the relation to hypertension. Normal value of serum potassium in both sexes was considered as 3.5-.5.5 mmol/L.Results:Mean serum potassium level of stroke patients was significantly lower than that of control group (3.89±0.67 versus 4.19±0.56, p=0.0001). Hypokalemia was found in 23 (23%) patients with stroke compared to 7 (7%) of the control group. The Mean serum potassium in hypertensive patients was significantly lower than those without hypertension (3.91 ±0.65 versus 4.2 ±0.54). The mean serum potassium for hypertensive stroke patients was significantly lower than non-hypertensive stroke patients (3.79±0.78 versus 4.26±0.72), while there was no significant difference among the control hypertensive and non-hypertensive subjects (4.05±0.57 versus 4.43±.40).Conclusions:Serum potassium should be taken in consideration as low levels are significantly associated with ischemic stroke with hypertension.Keywords:Serum Potassium, ischemic stroke


Article
Assessment of Endogenous Erythropoietin Level in Sera Patients with Acute Ischemic Stroke

Authors: Suhayr Aesa Al-Qaysi --- Afaf K. Shweekh --- Zinah Abbass Ali
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2015 Volume: 12 Issue: 1 Pages: 132-138
Publisher: Babylon University جامعة بابل

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A stroke is the loss of brain function due to a disturbance in the blood supply to the brain. Ischemic type is the most common type of stroke in older adults, caused by either blockage of a blood vessel via thrombosis or arterial embolism, or by cerebral hypoperfusion. Erythropoietin (EPO) is a glycoprotein hormone that controls erythropoiesis, or red blood cell production. This study aimed to explore the EPO level in serum of ischemic stroke patients during the acute phase. This study was included 40 subjects, 20 patients with acute ischemic stroke and 20 apparently healthy persons act as a control group. Five milliliters of blood were collected in plane tube without anticoagulants for measuring EPO level in sera of patients and control by ELISA technique. In comparison with the control group, the patients with acute ischemic stroke showed a significant increase in EPO level (P ˂ 0.002). our data revealed that increase circulating endogenous EPO as a response to hypoxia and thereby increase oxygen supply by inducing erythropoiesis and/or other stimulatory factors that contribute the ischemic tolerance.


Article
Electrocardiographic changes in acute ischemic stroke In Kirkuk : Azadi teaching hospital

Author: Younis Esmaeel Ebraheem
Journal: The Medical Journal of Tikrit مجلة تكريت الطبية ISSN: 16831813 Year: 2016 Volume: 2 Issue: 2 Pages: 216-219
Publisher: Tikrit University جامعة تكريت

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Article
Management and Outcome of Stroke in a Sample of Children Admitted to Children Welfare Teaching Hospital/Baghdad

Author: Nebal Waill Saadi Al-Dabbas*, Batool Ali Ghalib Yassin**, Ahmed Mahdi Ibrahim***, Waleed Khalid Abbas Ageedi****
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2016 Volume: 15 Issue: 2 Pages: 194-201
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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ABSTRACT:BACKGROUND: Stroke in children is a serious disorder in which little has been published. Population-based estimates of the annual incidence of childhood stroke (ischemic and haemorrhagic) range from 2•3 to 13•0 per 100 000 children and incidence rates in neonates are closer to 1 per 5000 live births CONCLUSION:To determine clinical presentation, etiologies, diagnostic procedures, treatment options and outcome of children with stroke.METHODS: Descriptive study of patients with stroke admitted to Children Welfare Teaching Hospital/Baghdad from October 2011 to September 2012 was conducted. Cases were classified radiologically into ischemic stroke (IS) and hemorrhagic stroke (HS) and their management modalities were studied.RESULTS: Out of 21 patients; 13 (61.9%) had hemorrhagic and 8 (38.1%) had ischemic stroke. Female:male ratio was 1.3:1. Haemorrhagic stroke was more among males and infants; ischemic stroke was more among females and older children. In 16 (76%) patients, the diagnosis was established after more than 24 hours of onset. Patients with ischemic stroke spend longer time in hospital. Seizure was the commonest clinical feature in both types (17 patients (81%)) followed by altered mental status (16 patients (76.2%)). CT-scan was abnormal in 20 patients and MRI in 11 patients. Complete recovery was noticed in 7 (54%) patients with hemorrhagic type, while 7 (87.5%) patients with ischemic type recovered with sequelae.CONCLUSION: Stroke was more common among female and children younger than 12 months. Seizure and altered mental status were the commonest presentations. A delay in performing neuroimaging was obvious in the current study. Patients with ischemic stroke tend to spend longer time in hospital. Antibiotic were the medication most often used. The majority of children were discharged well. .


Article
The incidence of stress hyperglycemia in acute ischemic stroke patients (in Al-Yarmouk teaching hospital)

Authors: Abdul- Hameed Al-Kassir --- Zaid Tarik زيد طارق
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2012 Volume: 11 Issue: 1 Pages: 46-51
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Aims: Stress hyperglycemia represents a transient increase in blood glucose in reaction to acute illness. Cases with stress hyperglycemia have higher mortality rates and worse functional outcomes than the ones with known diabetes or normoglycemia. This study evaluated the incidence of stress hyperglycemia in acute ischemic stroke patients and its relationship with stroke risk factors. Patients and Methods: WHO criteria is used to confirm hyperglycemia and HbA1c test to detect stress hyperglycemia in a sample of 220 patients with acute ischemic stroke who were admitted to Al-Yarmouk teaching hospital in Baghdad from 1 April to 31 December 2010. Results: thirty nine patients with acute ischemic stroke had stress hyperglycemia. There is significant effect of gender, hypertension, atrial fibrillation and dyslipidemia on patients with stress hyperglycemia while this is not found with obesity and smoking.Conclusions: stress hyperglycemia is a common phenomenon in patients who develop acute ischemic stroke.


Article
Mean Platelet Volume And Its Influence on The Severity of Acute Ischemic Stroke

Author: Basim A. Abd
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2014 Volume: 11 Issue: 3 Pages: 500-506
Publisher: Babylon University جامعة بابل

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Abstract

Introduction and objective e: Mean platelet volume (MPV) values in association with both thrombosis and inflammation have become a point of interest in the last few decades, and some studies have reported MPV values significantly higher in patients with stroke. This study aims to determine if there is an association between elevated levels of MPV and the severity of acute ischemic brain stroke.Patients and methods: Fifty acute ischemic stroke patients who were admitted to Merjan Teaching Hospital in Al-Hilla City, Babylon-Iraq; during the period from October 2013 to April 2014 were enrolled in this study. They included 22 males and 28 females, their ages ranged from 50-90 years, with a mean age of 70.52±11.264 years. Those patients were divided into two groups based on modified Rankin Scale (mRS): Group 1 (mRS 0-2), group 2 (mRS≥3). This scale was used to assess the severity of the disease. Blood samples were collected from the patients to measure MPV.Results: The study demonstrated that the patients' group with mRS≥3 were significantly older than the other group regarding the age distribution, and MPV values for them were also significantly higher than the other group. Concerning the gender distribution and clinical history of ischemic heart disease and smoking, there were no significant differences between the two groups of patients. Conclusion: Mean platelet volume is a strong and independent risk factor for acute ischemic stroke and high MPV values could be associated with a severe form of the disease.

المقدمة والهدف: معدل حجم الصفيحات الدموية وبالمصاحبة مع كل من عمليتي التخثر والالتهاب أصبحوا موضع اهتمامٍ في العقود القليلة الأخيرة، وسجلت بعض الدراسات مستوياتٍ معنوية مرتفعة لمعدل حجم الصفيحات الدموية لدى مرضى السكتة الدماغية. تهدف هذه الدراسة إلى معرفة ما إذا كان هنالك ارتباطٌ بين المستويات المرتفعة لمعدل حجم الصفيحات الدمويّة وشدة السكتة الدماغية الإقفاريّة الحادة.المرضى وطرق العمل: تضمنت الدراسة خمسين مريضاً مصابين بالسكتة الدماغية الإقفاريّة الحادة ممن أُدخلوا إلى مستشفى مرجان التعليمي في مدينة الحلة، بابل-العراق، خلال الفترة من تشرين الأول 2013 إلى نيسان 2014. ضمن المرضى كان هنالك 22 ذكراً و28 أنثى تراوحت أعمارهم بين 50-90 سنة، وبمعدل عمري هو 70,52±11,264 سنة. قُسِّم المرضى إلى مجموعتين استناداً إلى مقياس رانكين المعدّل: المجموعة الأولى (0-2) حسب مقياس رانكين، والمجموعة الثانية (3 فأكثر) حسب نفس المقياس. استُخدم هذا المقياس لقياس شدة المرض. جُمعت عينات دمٍ من المرضى لقياس معدل حجم الصفيحات الدمويّة.النتائج: أظهرت الدراسة أن مجموعة المرضى الثانية حسب مقياس رانكين كانت بصورة معنوية أكبر عمراً من المجموعة الأولى، كذلك كانت مستويات معدل حجم الصفيحات الدمويّة لديهم أعلى معنوياً من المجموعة الأخرى. فيما يخص توزيع الجنس وكذلك التاريخ المرضي السريري لمرض القلب الإقفاري والتدخين فلم يكن هنالك فروقٌ معنويّة بين مجموعتيّ المرضى.الاستنتاج: معدّل حجم الصفيحات الدمويّة عامل خطورة قوي ومستقل للسكتة الدماغية الإقفاريّة الحادة والمستويات المرتفعة لمعدل حجم الصفيحات قد تكون مرتبطة بشكلٍ حاد من أشكال المرض.


Article
SERUM HDL IN PATIENTS WITH ISCHEMIC STROKE - A CASE CONTROL STUDY

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Background:Elevated high-density lipoprotein cholesterol (HDL-C) levels have been shown to be protective against cardiovascular disease. However, the association of specific lipoprotein classes and ischemic stroke has not been well defined.Objectives:To evaluate the association between HDL-C and ischemic stroke in men and women, and to compare the results with a control sample of the same age group.Methods:A hospital based case-control study was done comparing serum HDL-C levels in 48 ischemic stroke patients to 50 controls recruited from Al-Imamain Al-Kadhemain Medical City, all patients and control had negative past medical history, negative history for smoking and alcohol. Serum lipid profile was determined in all of them.Results :This study showed that regarding the serum HDL-C levels, 41 (85.4%) patients were found to have low levels (less than 40 mg/dl) while among the control group, only 19 (38%) have shown low serum HDL-C level.Conclusion:The study showed that there is a significant association between the low level of serum HDL-C cholesterol and the risk of ischemic stroke in this population.Keywords: cholesterol, lipoproteins, HDL-cholesterol, ischemic stroke


Article
The role of von Willebrand factor in determining the risk of ischemic stroke in Hawler city: a case-control study
دور عامل فون ويلبراند في تحديد خطر الإصابة بالسكتة الدماغية في مدينة هولير: دراسة الحالات و الشواهد

Authors: Salar Adnan Ahmed --- Sazgar Anwar Hameed
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2018 Volume: 22 Issue: 1 Pages: 120-125
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objective: Ischemic stroke is classically characterized as a neurological deficit attributed to an acute focal injury of the central nervous system by a vascular cause, it occurs as a result of obstruction by a blood clot (thrombus) or plugs within a blood vessel supplying blood to the brain. In this study, we investigated the association of von Willebrand factor-antigen and serum lipids with ischemic stroke.Methods: The following retrospective study was conducted on 138 participants; 88 patients with ischemic stroke and 50 healthy controls.Results: In crude analyses, Plasma von Willebrand factor antigen, fasting serum Total cholesterol, Triglycerides and LDL-C were significantly higher in patients with ischemic stroke than in controls (P <0.001, P <0.001, P = 0.003, P <0.001, respectively), while the difference in the level of serum HDL-C between patients with ischemic stroke and control was significantly lower (P = 0.023).Conclusion: These data suggest that von Willebrand factor, total cholesterol, triglycerides, LDL-C and HDL-C gives some contribution to stroke risk even in the elderly and that von Willebrand factor antigen and lipid profile assessment must be taken into account in estimating the individual risks of stroke.


Article
The role of spiral Computerized Tomography in diagnosis of stroke
تقييم كفاءة المفراس الحلزوني في تشخيص الجلطة الدماغية

Author: Eman I. Mohammed
Journal: nursing national Iraqi specility المجلة العراقية الوطنية للعلوم التمريضية ISSN: 18122388 Year: 2013 Volume: 26 Issue: 2 Pages: 123-128
Publisher: Baghdad University جامعة بغداد

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Objective: The aim of this study is to determine the role of spiral Computerized Tomography in the diagnosis and detection the types of stroke.Methodology: One hundred sixty two patients (162) (99 males and 63 females) their ages ranging from (13 – 80) year, all of them are suffering from stroke. They were collected randomly from spiral Computerized Tomography unit in Baquba Teaching hospital during the period from November / 2010 to December / 2011 .All the patients were examined clinically and then done spiral Computerized Tomography examination.Results : The results of this study showed that the stroke effected different age groups and both sex but males is more affected than the females .The results of spiral Computerized Tomography examination were 97 patient ( 59.9 % ) have ischemic stroke and 65 patient ( 40.1 % ) have hemorrhage stroke .Recommendation: The study recommended that great focusing to do the examination by spiral computerized tomography if the patients have no contraindications for during examined with it because it has high accuracy and efficiency in diagnosis of the stroke, also recommended to do an educational programs to improve awareness of society about the risk factors and early clinical features to help of early diagnosis and management of stroke.

الهدف : تهدف الدراسة إلى معرفة كفاءة المفراس الحلزوني في تشخيص وتحديد أنواع الجلطة الدماغية .المنهجية : تم فحص ( 162 ) مريضا ( 99 من الذكور و 63 من الإناث ) وكانت أعمارهم تتراوح بين ( 13 – 80 ) سنة وجميعهم كانوا يعانون من الجلطة الدماغية . جمعت العينات بطريقة عشوائية من وحدة المفراس الحلزوني في مستشفى بعقوبة التعليمي خلال الفترة من نوفمبر 2010 – ديسمبر 2011 وتم فحص جميع المرضى سريريا" ومن ثم اجري الفحص بواسطة جهاز المفراس الحلزوني . النتائج : من خلال هذه الدراسة تم التوصل الى نتائج تفيد إن الجلطة الدماغية تصيب مختلف العمرية وكلا الجنسين ولكن الذكور أكثر عرضة للإصابة بالجلطة الدماغية من الإناث . اظهرت نتائج الفحص بواسطة جهاز المفراس الحلزوني ان 97 مريضا ( 59,9 % ) مصاب بالجلطة الخثرية و65 مريضا ( 40,1 % ) مصاب بالجلطة النزفية . التوصيات : أوصت الدراسة بالتأكيد على إجراء الفحص بواسطة جهاز المفراس الحلزوني إذا لا توجد أية خطورة على المريض عند الفحص لأنه ذو دقة وكفاءة عالية في تشخيص الجلطة الدماغية وكذلك أوصت الدراسة بضرورة اعداد برامج توعية لتحسين معلومات الأشخاص حول عوامل الخطورة والعلامات السريرية المبكرة للجلطة الدماغية لكي تساعد في التشخيص والعلاج في وقت مبكر .


Article
Thyroid Function Tests in Patient with Ischemic Stroke

Authors: Ahmed Abdul-Jawad Salim --- Kareem M. Al-Tameemi --- Akram Mohammed Al-Mahdawi
Journal: Karbala Journal of Medicine مجلة كربلاء الطبية ISSN: 19905483 Year: 2013 Volume: 6 Issue: 2 Pages: 1694-1702
Publisher: Kerbala University جامعة كربلاء

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bjectives: To analyze thyroid functions tests in patients with ischemic stroke at acute stage and to study the association between ischemic stroke and different types of thyroid dysfunctions.Methods: A hospital based, cross-sectional, case-control study with trial to cancel the role of age, gender, hypertension and diabetes mellitus as confounding factors was adopted to achieve the aim of this study. A total number of 210 cases (105 as patients group presented with ischemic stroke and another 105 case as control group not suffering from ischemic stroke) were examined for TSH, T4 and T3. The period of data collection was from Jan. 2011 to the end of Jan. 2012. The patients were collected from the wards of neurology while the control group were collected from the out patients clinic, of Baghdad Teaching Hospital, Baghdad, Iraq.Ischemic stroke was confirmed by their clinical picture and native brain CT scan. Exclusion and inclusion criteria, definition of variables and the consents from all patients were fulfilled.Results: 8.6% of ischemic stroke patients showed hypothyroid pattern, 8.6% hyperthyroid pattern and 3.8% sick euthyroid pattern and these results were statistically significant as compared with control cases. 7.6% of patients had atrial fibrillation (AF) statistically of significant difference. Most cases of AF registered among patients with hyperthyroidism 60%. 12.7% of patients with hypothyroid pattern had statistically significant obesity and 8% of patients with sick euthyroid pattern had diabetes which was also significant.Conclusions: Both hyperthyroidism and hypothyroidism might be considered as risk factors for developing ischemic stroke. Atrial Fibrillation may be a predictor for developing ischemic stroke especially in patients with hyperthyroidism. In hypothyroidism, there may be an association of several atherosclerotic risk factors with ischemic stroke. Sick euthyroid is not uncommon in patients with ischemic stroke which reflect the increase in physical stress associated with the insult.

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