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Article
COMPARATIVE STUDY OF THREE METHODS OF TONSILLECTOMY IN DOGS
دراسة مقارنة ثلاث طرائق لاستئصال اللوزتين في الكلاب

Author: MJ Eesa محمد جواد عسى
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2007 Volume: 6 Issue: 2 Pages: 18-24
Publisher: Basrah University جامعة البصرة

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Abstract

Eleven dogs were used in this study. The animals were divided into three groups: group one, in which the tonsil glands were ligated and then resected by scalpel; group two, the tonsils resected by electrocautery; group three; the tonsils were excised by electrocautery with help of an laparoscope. The clinical findings, after two days of operation, at the excision sites appeared redness in color and slight swelling. These signs disappeared at 4-6 postoperative days in group one, while in second and third groups, it extend for 5 - 7 days. Healing of surgical sites occurred 10-12 days after operation in the first group, while in second and third groups, healing occurred in 11-14 days, respectively. The modified use of a rigid laparoscopic toll in the third group for tonsillectomy, was found to be easy for application of the method and given good results.

أستخدم في هذه الدراسة (11) كلبآ قسمت فيها الحيوانات الى ثلاث مجاميع: ففي المجموعة الاولى تم ازالة غدة اللوزتين بواسطة المشرط الجراحي بعد اجراء الربط من قاعدة الغدة ؛ اما في المجموعة الثانية فتم ازالة الغدة بواسطة الكي الكهربائي ؛ وفي المجموعة الثالثة تم ازالة الغدة بأستخدام الة الكي الكهربائي وبمساعدة جهازالجراحة المنظارية. اظهرت العلامات السريرية بعد يومين من اجراء العملية الجراحية وجود احمرار وتورم في مكان الاستئصال. تلك العلامات اختفت بعد مرور 4-6 ايام من اجراء الأستئصال في المجموعة الاولى و 5-7 ايام في المجموعتين الثانية والثالثة. وحدث الالتئام لمكان العملية بعد 10-12 يومآ في المجموعة الاولى و11-14 يومآ في المجموعة الثانية والثالثة. ان الأستخدام المحور لجهاز الجراحة المنظارية في المجموعة الثالثة لاستئصال اللوزتين بواسطة الكي الكهربائي قد اعطت نتائج جيدة وذلك لسهولة الطريقة.


Article
ANATOMICAL AND HISTOLOGICAL STUDY OF THE SPLEEN IN IRAQI SHEEP(Awasi sheep)
دراسة تشريحية ونسيجية لطحال الاغنام العراقية (العواسية)

Author: Eman M. Khalel ايمان موسى خليل
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2010 Volume: 9 Issue: 2 Pages: 163-171
Publisher: Basrah University جامعة البصرة

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Abstract

This study were carried out on 20 healthy of spleen healthy adult Awasi sheep.The anatomical study include study of length, width Thickness, weight of 10 spleen.The average measurements were 9.93+0.342;6.48+0.233;2.48+0.142 cm and 69+6.663 gram respectively while the histological study include the thickness of capsule and trabeculae ,splenic white pulp diameter ,lymphoid nodule diameter were determind on 10 spleens.The average measurements were 140.5±13.712; 82.75±9.7; 505±34.245; 315.25±23.185 μ respectively. The periarterial lymphatic sheath (PALS) containing One central artery that branched into 2-3 arteries.

اجريت هذه الدراسة على0عينة طحال اخذت من اغنام بالغة نوع عواسي. تضمنت الدراسة التشريحية طول وعرض وسمك ووزن 10 عينات طحال وكان معدل القياسات9.93±0.342، 6.48±0.233، 2.48±.142سم، 69±6.663غم على التوالي بينما الدراسة النسيجية تضمنت سمك محفظة الطحال، سمك الحواجز الطحالية ، قطر اللب الابيض للطحال وقطر العقيدات اللمفية وكانت معدل القياسات 140.5±13.712،82.75±9.7، 505±34.245، 315.25±23.185، مايكرو على التوالي ، والغلاف اللمفي يحيط بشريان مركزي واحد والذي يتفرع 2-3 شرايين.


Article
5-EVALUATION OF INTRAYOLK SAC INOCULATION OF INFECTIOUS BURSAL DISEASE VACCINE ON IMMUNE RESPONSES IN NEWLY HATCHED BROILER CHICKS

Author: Harith A. Najem
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2018 Volume: 17 Issue: 1 Pages: 52-62
Publisher: Basrah University جامعة البصرة

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Abstract

A total of 60 one-day old Ross broiler chicks were used in this study. The birdswere divided into four groups. The first group A was vaccinated against IBD with a CevacIBD L vaccine at one-day old by intra-yolk sac method (lYS) with a dose of 0.5ml using a(1ml) syringe, whereas the second group B was vaccinated against IBD with the samevaccine at 14 days of age by drinking water method (DW). The third group C and fourthgroup D were considered as a positive and negative control respectively . On day 35, thebirds were weight and killed to collect blood samples and lymphoid organs wereremoved and weight to study the effects of (lYS) rout on body weight , lymphoid organweights and the humeral immune response to IBD vaccine which measured by ELISAtest. The results showed significant differences at (P≤0.05) in body weight of group A, inaddition significant (p<0.05) increase in the all lymphoid organs weight , Bursa offabricius (BF) was 1.643 a ±0.066 in group comparison with other groups which had beenrecorded 1.102 b ±0.022, 0.850 c ±0.067 in group B and C respectively. Group B indicatedthat was a significant decrease at (p<0.05) in the weight of of spleen which was 1.102 b± 0.022 in comparison to control groups. With regard to serological test, bird from groupA recorded higher Ab titer 24038 a± 685 compared to those of other groups , and thisincrement was statically significant (p<0.05), however both group A and B revealed a53significant differences( p <0.05) from the control groups. Generally the results indicatedthat intra-yolk sac method was highly effective rout of IBD vaccine administration

Keywords

Ross broiler --- IBD --- lymphoid organ


Article
Efficacy of Methionine supplementation on the Growth Performance and Lymphoid organs indices of Broiler Chickens Vaccinated with combined Infectious Bronchitis Newcastle disease Vaccines
فاعلية اضافة المثيونين على اداء النمو ومؤشرات الاعضاء اللمفاوية في دجاج اللحم الملقح معا بلقاحي التهاب القصبات المعدي والنيوكاسل

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Abstract

Methionine (Met.) is amino acid that has proven immune regulatory action. It is usually first limiting amino acid in maize and soybean meal based diet. Met. supplementation in growing chick is a common practice (Swick et al., 1990; Shini & Brydeen, 2005). One of the mechanisms proposed to explain Met. interference in the immune system is the proliferation of T cells, which are sensitive to intracellular glutathione and cysteine levels, compounds also participate in Met. metabolism (Kinscherf et al., 1994). The aim of this study was to investigate the efficacy of Methionine (Met) supplementation on the growth performance and lymphoid organs indices of broiler chickens vaccinated with combined infectious bronchitis (IB)Newcastle disease (ND) vaccines. A total of 120 newly hatched commercial broiler chicks were assigned into four equal treatment groups as follow: First group chicks were vaccinated against IB and ND at 8 and 21 days of age without Met. Second group chicks were vaccinated against IB and ND at 8 and 21 days of age with 0.5% Met. in the diet. Third group chicks remain as control group. Fourth group chicks remain as control group with 0.5% Met. in the diet. Body weight (BW), body weight gain (BWG), feed intake (FI) and lymphoid organs indices were estimated in all groups. Statistical analysis revealed significant (P<0.05) differences among the treatment groups in BW, BWG and better FI as compared with non treatment group. The mean value of thymus, bursa of Fabricius and spleen index of chicks supplemented Met during the period of age showed significant increment (P<0.05). We concluded that better growth performance and lymphoid indices could be obtained with adequate supplementation of Met which have been identified to be in marginal quantities in poultry feed.

ميثيونين حوامض أمينية التي يعمل في تنظيم للمناعة. هي حوامض أمينية محددة أولية عادة موجودة في الذرة الصفراء والصويا كوجبة طعام في العليقة. أضافة الميثيونين في عليقة الافراخ النامية شائع. أحدى الأليات المقترحة لتوضيح تدخل الميثيونين في نظام المناعة هو انتشار خلايا T, الذي حساس لمستويات الكليوتاثيون والسيستين, تشارك المركبات أيضا في أيض الميثيونين. ان هذه الدراسة تهدف إلى التعرف على فعالية اضافة الميثيونين على أداء النمو ومعدل وزن غدة التوثة, جراب فابريشا والطحال إلى وزن الجسم في الدجاج اللاحم الملقحة بلقاحي التهاب الشعب الهوائية المعدية ونيوكاسل. استعمل في هذه الدراسة 120 من افراخ الدجاج اللاحم التجارية بعمر يوم واحد قسمت هذه الافراخ إلى أربع مجموعات متساوية على النحو التالي في المعاملة: المجموعة الاولى ( (G1تم تحصين الافراخ ضد التهاب الشعب الهوائية المعدية ونيوكاسل في 8 و 21 يوما من العمر دون اضافة الميثيونين. المجموعة الثانية (G2) تم تحصين الافراخ ضد التهاب الشعب الهوائية المعدية ونيوكاسل في 8 و 21 يوما من العمر مع إضافة 0.5٪ من الميثيونين الى العليقة. المجموعة الثالثة (G3) عدت كمجموعة سيطرة. اما المجموعة الرابعة (G4) عدت كمجموعة سيطرة ولكن باضافة الميثيونين 0.5٪ الى العليقة.تم جمع البيانات من زيادة الوزن، الزيادة في وزن الجسم واستهلاك العلف من عمر (0-35) يوم. وكشف التحليل الإحصائي للبيانات وجود فروق معنوية(P<0.05) بين مجموعات المعالجة في الوزن وبالزيادة الوزنية. على اية حال، اظهر النتائج وجود زيادة بالوزن وبالزيادة الوزنية وزيادة استهلاك العلف في المجموعتين المضافة اليها المثيونين. وأظهر زيادة معدل قيم غدة التوثة, جراب فابريشا والطحال في الافراخ المضافة اليها الميثيونين خلال فترة التربية فروق معنوية .(P <0.05) خلصنا إلى أن أفضل أداء النمو ومؤشرات اللمفاوية يمكن الحصول عليها مع اضافة كافية من المثيونين التي تم تحديدها لتكون في الكميات الهامشية في أعلاف الدواجن


Article
The Value of Serum Ferritin in the Prediction of Iron Deficiency in Patients with Lymphoid Neoplasms

Authors: Ahmed I. Shuk --- Yassmin .Ali abdul-kareem AL-Amiri --- Yassmin .Ali abdul-kareem AL-Amiri Mahmood R. Al-Rubaye --- Zakaa N. Al-Nidawy --- et al.
Journal: Karbala Journal of Medicine مجلة كربلاء الطبية ISSN: 19905483 Year: 2013 Volume: 6 Issue: 2 Pages: 1668-1674
Publisher: Kerbala University جامعة كربلاء

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Abstract

background:- anemia is a well-known complication of patients with lymphoidneoplasm and many factors are involved in its pathogenesis including defective ironutilization and diagnosing iron deficiency in the context of malignancy or chronicillness can be very challenging as many of the parameters used are acute phase markers andcan be misinterpreted in the presence of chronic illness .bone marrow iron is the goldstandard mean for assessing marrow iron but it is an invasive and a laborious procedure ,onthe other hand serum ferritin has been used as the most relevant indicator of iron deficiencyin the general population but it has the drawback of being increased in the presence of anacute response.Objectives:- evaluate the ability of serum ferritin at different cutoff levels and incombination with other parameters to identify iron deficiency in patients with lymphoidneoplasms.Patients and methods:- 39 anemic patients with different types of lymphoid neoplasmattending the hematology unit in Baghdad hospital were enrolled in the study ,exclusioncriteria included history of blood transfusion and iron therapy in the past 2 months .for allpatients bone marrow iron study was carried out and accordingly patients were classified into2 groups the iron depleted group (with absent marrow iron) and the iron replete group (withpresent iron stores).from all patients peripheral blood was taken for the evaluation ofcomplete blood picture and ESR and serum ferritin by enzyme Linked immunosorbant assaymethod (ELISA).Results:- the mean serum ferritin for the iron depleted group was 78.31ng/dl while for theiron replete group it was 202.77ng/dl there was a highly significant difference for serumferittin between the 2 groups (p value .005),a less significant difference was found also forthe mean cell volume(p value .05) while the other parameters showed no difference, thelowest cutoff level for serum ferittin that could accurately identify iron deficiency with a highsensitivity 96% and a high specifity 80% was 66.7ng/dl . Logistic regression analysis wasdone for serum ferritin and ESR to test for the effect of these parameters on the predictivepower of bone marrow iron stores. The logistic equation was:Log (p)=0.163 + .0621*ESR -0.026*ferritinUsing this equation with ferritin and ESR gave a prediction power of about 74% to identifythe iron bone marrow store however using ferittin alone gave a 69% prediction power.Conclusion: - serum ferritin at a cutoff value of 66.7ng/dl can be used with high accuracy forthe identification of iron deficiency in patients with lymphoid neoplasm and can be used as asuitable alternative for bone marrow iron, correction of serum ferritin for the acute phaseresponse did not enhance much its predictive power in identifying iron deficiency in thosepatients.


Article
Evaluation of serum adenosine deaminase activity in acute lymphoid leukemia in Erbil city
تقييم نشاط مصل الأدينوزين في الدم في ابيضاض الدم الليمفاوي الحاد في مدينة أربيل

Authors: Sardar Nouri Ahmed --- Salim Khalid Mohammad
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2012 Volume: 16 Issue: 2 Pages: 151-156
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objectives: Adenosine deaminase (ADA), is an enzyme that catalyzes hydrolytic deamination of either adenosine or deoxy adenosine to produce inosine and deoxy inosine respectively. The aim of the present study is to evaluate the serum ADA activity in acute lymphoid leukemia.Method: A prospective study was carried out from January to June 2011 by the clinical biochemistry department in College of Medicine-Hawler Medical University on (30) patients with Acute lymphoid leukemia (group 1), and (30) healthy individuals, (group 2).Results: The mean value of serum ADA activity was significantly lower in Acute lymphoid leukemia (group 1), than those of healthy individuals, (group 2) (p<0.01), and both ions Na+ and K+ acted as an activators for Serum ADA activity.Conclusion: Based on the findings, it can be concluded that in acute lymphoid leukemia the activity of Serum ADA was decreased due to decline in the immunity.


Article
Association of human herpesvirus 6 with lymphoid malignancies in Iraqi patients

Authors: Hadeel M. Fiadh --- Alaa F. Alwan --- Dawood S. Dawood
Journal: Iraq Joural of Hematology المجلة العراقية لامراض الدم ISSN: 20728069/25432702 Year: 2015 Volume: 4 Issue: 2 Pages: 18-29
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Background: Human herpesvirus type 6 (HHV-6) is associated with roseola infantumduring childhood followed by life-long latency that periodically reactivated inimmunocompromised individuals. In spite of several studies to establish the pathogenicrole of HHV-6 in lymphoid malignancies, the issue is still controversial.Objectives: This study was arranged to explore the association of HHV-6 infection inlymphoid malignancies using different serological and molecular techniques and toquantify the plasma viral load.Patients and methods: This cross-sectional case control study was conducted inNational Center for Hematological Diseases (NCHD) at Al-Mustansiriyah Universityand Baghdad Teaching Hospital (BTH) in Baghdad-Iraq from September 2013 tillApril 2015. The patient group consists of 11 patients with Hodgkin lymphoma and39 Non-Hodgkin's lymphoma of both sexes. The age range was between 15-80 years.The diagnosis of lymphomas was based on hematological and histopathologicalcriteria. 59 apparently healthy individuals were enrolled as control group. They werechosen from unpaid blood donors. The age range was between 18-59 years. Humanprivacy was respected by taken participant's oral consensus. The seropositivity rate ofanti-HHV-6 IgG and IgM antibodies were detected by enzyme linked immunosorbentassay (ELISA) and indirect immunofluorescent test (IFAT). The molecular detectionand determination of plasma viral DNA load was achieved by quantitative polymerasechain reaction (qPCR). All data were statistically analyzed, and P values < 0.05 wereconsidered significant.Results: The anti-HHV-6 IgG positivity rate by IFAT was insignificantly higher in HL(81.8% vs 61.0% p=0.186) and NHL (64.1% vs 61.0%, p =0.758) compared to controlgroup. The anti-HHV-6 IgG positivity rate by ELISA was 81.8% in HL, 84.6% inNHL versus 72.9 % in controls which were insignificant in both groups (p=0.534 andp=0.173) respectively. The anti-HHV-6 IgM positivity rate by ELISA techniqueamong patients with HL was significantly higher compared to controls (27.2% vs 6.8%,p= 0.038), but not significant in NHL (17.9% vs 6.8%, p= 0.086). HHV-6 DNA wasdetected in (27.3%) patients with HL by PCR technique, but none of the controls orNHL patients was positive. The plasma viral DNA load of the patient with HL was1.4± 0.3 x105 copies/milliliter.Conclusion: Although a higher anti-HHV-6 antibodies positivity rate among patientswith HL and NHL, the pathogenic role of the virus in the development of thesemalignancies was difficult to be ascertain.


Article
The frequency of aberrant lymphoid antigens expression in 202 Iraqi patients with de novo acute myeloid leukemia

Authors: Wafaa Mohammed Al‑Anizi --- Mohammed Abdul Rassoul Al‑Mashta
Journal: Iraq Joural of Hematology المجلة العراقية لامراض الدم ISSN: 20728069/25432702 Year: 2017 Volume: 6 Issue: 2 Pages: 49-54
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

BACKGROUND: Immunophenotyping improves both accuracy and reproducibility of acute leukemiaclassification and is considered, particularly useful for identifying acute myeloid leukemia (AML) withlymphoid marker expression. The incidence of the aberrant phenotypes in AML is still controversial;incidences as high as 88% have been reported.OBJECTIVES: To evaluate the occurrence of aberrant lymphoid phenotypes and to correlate theirpresence with various French‑American‑British classification (FAB subtypes), 202 cases of newlydiagnosed AML were analyzed for lymphoid markers CD1a, CD2, CD3, CD4, CD5, CD7, CD8,CD10, CD19, CD20, and CD79a.MATERIALS AND METHODS: Whole blood or bone marrow aspirate of 202 patients with de novoAML was collected in ethylenediaminetetraacetic acid tube and analyzed by flow cytometry using alarge panel of fluorochrome‑labeled monoclonal antibodies. Identification of blast cells was performedusing forward scatter versus side scatter (SSC) parameters and CD45 intensity versus SSC dot plots.An antigen was considered positively expressed when at least 20% of the gated cells expressedthat antigen.RESULTS: Eighty‑five patients (42%) with de novo AML expressed lymphoid‑associated antigens.All AML subtypes demonstrated lymphoid‑associated antigens except M7. T‑cell aberrancy wasthe most common comprising 32.2% of the total aberrancy. The most frequently lymphoid antigenaberrantly expressed was CD7 (25.7%), followed by CD4 (22.4%) and CD19 (7.9%).CONCLUSION: A large number of AML cases showed aberrant lymphoid phenotypes. These lymphoidphenotypes might be associated with different leukemia subtypes. T‑cell markers are more commonthan B‑cell markers. CD7 was the most common lymphoid marker aberrantly expressed in AML.


Article
Morphological and histological study of the spleen in Hedgehog (Hemiechinus auritus
الوصف العياني والتركيب النسجي للطحال في القنفذ طويل الاذن Hedgehog (Hemiechinus auritus)

Author: Thekra Atta Ibrahim ذكرى عطا إبراهيم
Journal: Tikrit Journal of Pure Science مجلة تكريت للعلوم الصرفة ISSN: 18131662 Year: 2017 Volume: 22 Issue: 7 Pages: 13-21
Publisher: Tikrit University جامعة تكريت

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Abstract

The present study aimed to investigate the morphological description and histological structure of the spleen in Hedgehog (Hemiechinus auritus); the anatomical study revealed that spleen in Hedgehog was elongated, tongue-like shape, with blue red color. It is situated in the abdominal cavity in the left side of the stomach. The results of histological study revealed that the spleen was surrounded by a thick capsule composed of outer layer of mesothelial cells and an inner layer consist of dense fibrous connective tissue, contains collagen and elastic fibers with more smooth muscle fibers, trabeculae extend from dense fibrous connective tissue the capsule into the splenic parenchyma. The contained trabecular arteries, nerves and were composed mainly of connective tissue made of collagen, reticular and elastic fibers and more smooth muscle fibers. It is comprised of two functionally and morphologically distinct compartments, the red pulp and the white pulp. The white pulp was made of lymphatic nodules consists of the marginal zone forming the outermost edge of white pulp, the periarteriolar lymphatic sheeth (PALS), central arteries and germinal centers Containing the phagocytic and plasma cells and Retinae cells win lymphocytes of medium and small-sized. The present study revealed some of these terminate in the marginal sinus at the junction of the white pulp and the marginal zone, whereas others traverse the marginal zone to form the venous system of the red pulp, which named after the large, blood-filled sinuses. Histological examination also showed that the red pulp spleen in hedgehog composed from vascular tissue that contain pulp arteries, venous sinuses and splenic cords Within the spaces between the cords are megakaryocytes and blood cells. Results of the present study revealed that extramedullary hematopoiesis (EMH) a normal occurs of the splenic red pulp. Extramedullary hematopoiesis may include increased numbers of erythroid precursors, myeloid precursors, megakaryocytes

ھدفت الدراسة الحالیة إلى التعرف على الوصف العياني والتركیب النسجي للطحال (Spleen) في القنفذ طويل الأذن (Hemiechinus auritus). أظھرت نتائج الدراسة التشریحیة أن الطحال في القنفذ طويل الأذن يكون ذو شكل متطاول يشبة شكل اللسان ذو لون أحمر مزرق، ويقع في التجويف البطني الايسر للمعدة .وأظهرت نتائج الدراسة النسجیة أيضاً أن الطحال محاط بمحفظة سميكة تتالف من طبقة خارجية من الخلايا الميزنكيمية (Mesothelial cells) وطبقة داخلية من نسيج ضام ليفي كثيف يحتوي على ألياف مرنة وغراوية وألياف عضلية ملساء كثيرة. كما أظهرت الدراسة أن الطحال يتميز الى منطقتين متميزتين ومختلفتين في الشكل والوظيفة وهما اللب الابيض (White pulp) واللب الاحمر (Red pulp). يتكون اللب الأبيض من العقيدات اللمفية (lymphatic nodules) تحتوي على المنطقة الحافية والغمد اللمفاوي المحيط بالشرين المركزي (Central arteriole) والمركز الجرثومي (Germinal center) بينما اللب الأحمر يتكون من نسيج لمفي شبكي وعائي يحتوي على شرينات لبية وجيوب وريدية والحبال الطحالية اللمفية ويوجد داخل الفراغات بين الحبال الطحالية خلايا بطانية (Reticular endothelium) وخلايا دم كثيرة. كما أظهرت الدراسة أن عملية تكون الدم خارج النقي يحدث بصورة طبيعية في اللب الاحمر والتي تتمثل بتكوين سليفات الدم الاحمر ((Erythroid وسليفات النقي (Myeloid) وخلية النواء (Megakaryocytes).


Article
The Effect Of Formaldehyde On The Lymphoid Tissues Of Rats( Quantitatine And Histological Study)
تأثير فورمالديهايد على أنسجة اللمفاوية الجرذان (دراسة Quantitatine ونسيجية

Authors: Maha Al Sammak عايد السرجي ، الياس شعيا،مها علي --- Elias Shaya --- Ayad Al – Saraj
Journal: The Medical Journal of Tikrit مجلة تكريت الطبية ISSN: 16831813 Year: 2006 Volume: 1 Issue: 121 Pages: 76-85
Publisher: Tikrit University جامعة تكريت

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Abstract

This study is concerned with the effect of formaldehyde on the lymphoid system by
quantitative and histological analysis. For this purpose 4 groups , each of 8 male rats were
examined , group I lefts as a control , while group II,III and IV had given oral administration of
10% formaldehyde (10 mg /kg body weight /day ) for 30, 60 and 90 days respectively . Two
lymphoid organs , spleen and iliac lymph node were examined . The results showed
significantly decreased of body weight during long period of formaldehyde exposure . In
general a significant decrease were observed in organ weight , standardized weight , total white
cell count , cell density and differential white cell count in the treated groups and especially
during long period of exposure. Histologically, a significant decrease was observed in the number
and the percentage of while pulp of spleen, and in the number of nodules and the percentage of the
diameter of the cortex of the iliac lymph node. These results showed that the formaldehyde caused
a marked involution of the lymphoid system and this might be due to decreasing in cell-mediated
immunity and humoral immunity leading to immunosuppression.

وتشعر هذه الدراسة مع تأثير الفورمالديهايد على النظام اللمفاوية بواسطة تحليل />
وفحصها، المجموعة الأولى اليساريين كعنصر تحكم، في حين أن المجموعة الثانية والثالث والرابع قد أعطى عن طريق الفم من
الفورمالديهايد بنسبة 10٪ (10 ملغم / كغم من الجسم الوزن / يوم) لمدة 60 و 30 و 90 يوما على التوالي. تم فحص اثنين
والأجهزة اللمفاوية والطحال والحرقفي العقدة الليمفاوية. أظهرت النتائج
وانخفضت بشكل ملحوظ من وزن الجسم خلال فترة طويلة من التعرض للفورمالدهيد. في
وعام لوحظت انخفاض ملحوظ في وزن الجهاز، الوزن موحدة، ومجموع الكريات البيضاء />
خصوصا خلال فترة طويلة من التعرض لها. تشريحيا، لوحظ وجود انخفاض ملحوظ في عدد
والنسبة المئوية للبينما اللب من الطحال، وعدد من العقيدات ونسبة القطر />
وارتداد واضح من النظام اللمفاوية، وهذا قد يكون راجعا الى انخفاض في الخلية بوساطة حصانة />

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