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Article
Enzyme linked immunosorbent assay (ELSA) investigation for Human Kisspeptin and progesterone Levels in female having regular menstrual cycle

Author: Ahsan K. Abbas احسان كاظم عباس
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2011 Volume: 53 Issue: 2 Pages: 211-215
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Kisspeptin the product of the gene Kiss1 is a G-protein coupled receptor legend for GPR54. Kiss1 was originally identified as a human metastasis suppressor gene that has the ability to suppress melanoma and breast cancer metastasis. It is recently become clear that kisspeptin-GPR54 signaling has an important role in initiating GnRH secretion at puberty, the extent of which is an area of ongoing research.
Objective: The present study was designed to determine the change of plasma kisspeptin levels during the menstrual cycle
Materials & Methods: A total of 20 women from friends and relatives pool were involved in this study. Selected from frinds and relative .They were selected after measuring their progesterone level on day 21 of menstrual cycle (excluding women who have anovulate menstrual cycle; low level of progesterone) , and then on 1 -5 day of the next menstrual cycle. All measurements were done in Teaching laboratories in Baghdad Teaching Hospital in Baghdad/Iraq. Five mls of blood withdrawn from each selected women by veinpuncture of selected women. ELISA technique was used for the measurement of serum kisspeptin -1and progesterone level. Data were expressed as a mean ±SD. Results were evaluated using the student t-test for paired data. Conventional methods were used for the correlation and regression analyses.
Results: Results obtained showed that the levels of serum kisspeptin and progesterone were significantly higher on day 21of menstrual cycle than during menstruation period with p<0.01, also it was found a significant positive correlation of kisspeptin level with progesterone level (r= 0.77 ,p<0.01).
Conclusion: The results determine the role of kisspeptin on ovulation, and give a possibility for its beneficial manipulation of human fertility.


Article
The Relationship between the Presence of Uterine Fibroid and Symptoms in Women 20-40 Years Old

Authors: Muna Kasim Mahmood --- Zena Mahdi Abd Ali
Journal: Karbala Journal of Medicine مجلة كربلاء الطبية ISSN: 19905483 Year: 2014 Volume: 7 Issue: 1 Pages: 1793-1796
Publisher: Kerbala University جامعة كربلاء

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Abstract

Abstractbackground: we examined the prevalence of uterine fibroid and menstrual cycle characteristics in a population of non-care-seeking women.Methods: this is a cross- sectional study involves 175 women who were not lactating or using contraception and their age between 20-40. After taking history transvaginal ultrasound done to these female. We examined the association between menstrual cycle characteristic and the presence of uterine fibroid.Results & discussion: uterine leiomyomata were detected in 31 women (17.71%). The presence of uterine leiomypma was not significantly related to amount of blood loss with menstrual cycle, regularity of the cycle, dysmenorrheo or deep pelvic pain.Conclusion: in this population of non-care seeking women, menstrual cycle abnormalities are not related to the presence of uterine leiomyoma.Keywords: Uterine Fibroid, Menstrual cycle, uterine, Leiomypma


Article
Pain Perception to Orthodontic Tooth Movement during Menstrual Cycle: A Clinical Study

Author: Munad J. AL_Duliamy
Journal: Tikrit Journal for Dental Sciences مجلة تكريت لعلوم طب الاسنان ISSN: 20731213 Year: 2018 Volume: 6 Issue: 1 Pages: 33-37
Publisher: Tikrit University جامعة تكريت

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Abstract

Pain during orthodontic treatment is inevitable side effect. Therefore, it is the responsibility of the orthodontist to alleviate this pain as possible. Menstrual cycle is often a painful event to female. Female is the most of orthodontic patient. Hence, study the pain perception of female to orthodontic treatment during menstrual cycle is essential. Aim: the aim of the present study is to asses, if there is change in pain perception to orthodontic tooth movement during menstrual cycle. Seventeen healthy female with regular menstrual cycle intended to receive orthodontic treatment with fixed appliances were participated in the study. Elastomeric separators were placed mesial and distal to maxillary and mandibular first molars during the menstrual and postmenstrual period respectively. Visual analog scale (VAS) was used to assess pain perception at 4 hours, 24 hours, 2nd, 3rd, 4th and 5th days after the separators were placed. Data of VAS scores were statistically analyzed. There were statistically significant increase in the pain perception level after the insertion of separators during menstrual cycle period and decrease during postmenstrual period. During menstrual cycle, female experienced higher pain perception to orthodontic tooth movement. Hence, it is better to postpone orthodontic visits for female patients to postmenstrual period.


Article
Variation of Glucose Concentration During Different Phases of Menstrual Cycle

Author: Maysaa Jalal Majeed
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2011 Volume: 10 Issue: 1 Pages: 73-77
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND:A woman's menstrual cycle (and accompanying hormonal changes) can cause variations in blood glucose levels. Many women may note an increase in their blood glucose after ovulation, which then decreases once menstruation starts. These changes are caused by the hormones estrogen and progesterone, which occur at higher levels before period. They influence insulin in causing blood glucose to rise. It is important to test blood glucose levels during this cycle to be certain that blood sugar variations are attributed to menstruation.OBJECTIVE:To study the effect of sex hormones (testosterone, estradiol and progesterone) on the level of glucose; as well as it may shed light on suitable dose of diabetic treatment during different phases of menstrual cycle.SUBJECTS & METHODS:This study included 50 healthy female with regular menstrual cycle aged 25-40 years (control group) and 25 diabetic type2 (well controlled) female with regular menstrual cycle aged 30-40 years. Serum fasting glucose and sex hormones (testosterone, progesterone and estradiol ) were evaluated in these two groups of patients and controls during follicular and luteal phases of sexual cycle. Colorimetric method was used in the serum glucose concentration determination, Enzyme Linked Immune Sorbent assay (ELISA) was used in the determining sex hormones level.RESULTS:The results of the present revealed significant increase in mean (+SD) values of serum glucose (p<0.05) and serum progesterone levels (p<0.05) with significant decrease of serum estradiol mean (+SD) values (p<0.01) in lateual phase than follicular phase of menstrual cycle of healthy women.Similar findings were found in diabetic women who have regular menstrual cycle .Serum glucose and serum progesterone showed significant increase ,while serum estradiol showed significant decrease in the luteal phase compared with follicular phase .No significant difference was found serum testosterone level in the above studied groups between the phases.It was found that 22% of healthy women with regular menstrual cycle showed elevation in their serum glucose concentration during the luteal phase of their sexual cycle.CONCLUSION:The study revealed that blood glucose level changes along the period of menstrual cycle , due to the interaction between the hormones that control menstruation (estrogen and progesterone ) and the insulin hormone


Article
The Effect of Glycemic Control on Menstrual cycle in Iraqi Diabetic Women
بيان تاثير السيطرة الايضية على اضطرابات الدورةالشهريةعند النساء العراقيات المصابات بالسكري

Author: Ghalib A. Al-Sharefi د.غالب عبد زيد الشريفي
Journal: IRAQI JOURNALOF COMMUNITY MEDICINE المجلة العراقية لطب المجتمع ISSN: 16845382 Year: 2009 Volume: 22 Issue: 3 Pages: 174-178
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Objective: - The study was designed to evaluate the importance of glycemic control on menstrual cycle disorders in Iraqi diabetic women.Setting: - The study was held at Department of Physiology, Medical College of Al-Mustansiriya University in cooperation with the Iraqi National Diabetes Center (NDC) of Al-Mustansiriya University in Baghdad from November 2004 till November 2005.Outcomes measures: - The glycemic control was assessed by estimation of glycosylated hemoglobin and fasting plasma glucose while the pelvic ultrasound and hormonal measurements were done for detecting menstrual disorders and state of ovarian function. The Follicular Stimulating Hormone FSH, The Lutenizing Hormone LH, Estrogen and progesterone were measured by using Enzyme Linked Fluorescent Assay technique (ELFA). Results: -The present study showed that menstrual disorders disorders are more common in diabetic than non-diabetic females. Diabetics with menstrual disorders (i.e. amenorrhea or oligomenorrhea) had anovulatory cycles with normal or low gonadotrophine and low progesterone levels, and it is more common in poorly controlled diabetics than those with good glycemic control. The polycystic ovarian syndrome was found to be associated with insulin resistance, obesity and glucose intolerance and is more common in diabetics than non-diabetic women.Conclusion: - The study revealed that good glycemic control in diabetic women exerts a positive influence on menstrual cycle regulation and on ovarian and gonadotrophic hormones.Keywords: -Menstrual cycle, ovarian function, glycemic control, polycystic ovarian syndrome.

الاهـــداف : - صممت هذه الدراسه لتقيم اهمية السيطرة الإيضية على اضطرابات الدورة الشهرية عند النســــــــاء العراقيات المصابات بداء السكري .مكان البحث :- اجريت هذه الدراسة بالتعاون بين قسم الفسلجة لكليةالطب/ الجامعة المستنصرية والمركزالوطـــــــني للسكري التابع للجامعة المستنصرية للفترة من تشرين اول 2004لغاية تشرين اول 2005 القياسات : - تم قياس مدى السيطرة الايضية بواسطة حساب خضاب الدم المسكر ونسبة الكلوكوز في بلازما الدم في وهرمــــــونFSH حالة الصيام بينما تم قياس مستوى الهرمونات الانثوية ( الهرمون المحفز للبيوض وهرمون الأستروجين والبروستيرون ) بواسطة المقايسة المناعية الانزيميـــــــــــــة LH الاباضة *. وتم قياس مدى نضوج البيوض داخل المبيض وتحديد وقت الاباضة بواسطة جهاز الامواجEIFA فوق الصوتية **.النتائـــــج :- اظهرت الدراسة بأن اضطرابات الدورة الشهرية تكون أكثر عند النساء المصابات بالسكري مما هي في سائر النساء ، وان النسوة اللواتي يعانين من اضطرابات الدورة الشهرية (غياب الدورة الكامل او الجزئي ) تكون الدورة الشهرية لديهن خالية من الاباضة ((عدم نزول البيضة اثناء الدورة الشهرية )) مـــــــــع مستوى اقل من هرمون البروجستيرون ، وهذة الاضطرابات تكون مصاحبة اكثر لضعف السيطرة الايضية للمصاب بالسكري مقارنة مع المصابات بالسكري ولديهن سيطرة ايضية جيدة . وكذلك وجدنا بأن ظاهرة تكيس المبايض المتعدد تكون مصاحبة اكثر للمصابات بالسكري مصحوبة مع مقاومة الانسولين و السمنة وعدم تحمل فحص تحدي الكلوكوز .الاستنتاجات :- بينت الدراسة بأن السيطرة الايضية الجيدة عند المصابات بالسكري لها تأثير ايجابي على انتظام الدورة الشهرية وكذلك على مستوى الهرمونات الانثوية الصادرة من المبيض او المراكز العليا للدماغ .


Article
premenstrual syndrome and its relation to motivation towards job achievement among female employees at Qadisiyah University
متلازمة الطمث وعلاقتها بالدافعية نحو الانجاز الوظيفي لدى الموظفات في جامعة القادسية

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Abstract

The study aims to identify premenstrual syndrome and its relation to motivation towards the achievement of career among female employees at the University of Qadisiyah. The number of sample (200) employee selected by the simple random way. In order to measure this goal, a measure of premenstrual syndrome and a measure of motivation towards functional achievement were developed. The researcher of the research tools extracted the conditions of vertebral analysis, honesty and persistence. The most important results of the study indicate that the employees of Qadissiya University include premenstrual syndrome, low motivation towards job achievement, and that there is a positive relationship between premenstrual syndrome and motivation towards job achievement among the employees of Qadisiyah University.

تهدف الدراسة إلى تعرف متلازمة الطمث وعلاقتها بالدافعية نحو الانجاز الوظيفي لدى الموظفات في جامعة القادسية. وبلغ عدد أفراد العينة (200) موظفة اختيروا بالطريقة العشوائية البسيطة. ولغرض قياس هذا الهدف تم بناء مقياس متلازمة الطمث، ومقياس الدافعية نحو الانجاز الوظيفي، وقد استخرجت الباحثة لأدوات البحث شروط تحليل الفقرات والصدق والثبات. تشير أهم نتائج الدراسة إن موظفات جامعة القادسية يتسمن بمتلازمة الطمث، وتدني الدافعية نحو الانجاز الوظيفي، وان هناك علاقة ايجابية بين متلازمة الطمث والدافعية نحو الانجاز الوظيفي لدى موظفات جامعة القادسية.

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