research centers


Search results: Found 19

Listing 1 - 10 of 19 << page
of 2
>>
Sort by

Article
Predictors of Perinatal Outcome in Full term Neonates with Hypoxic Ischemic Encephalopathy.

Authors: Rihab S. Rasheed --- Mohamoud Shehab --- Muhi K. Aljanabi محي كاظم الجنابي
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2011 Volume: 53 Issue: 2 Pages: 132-135
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background:Hypoxic ischemic encephalopathy (HIE) means failure to establish effective spontaneous breathing after complete delivery & leads to many changes if not diagnosed or treated immediately as mental retardation, cerebral palsy and epilepsy.Objective:to study the demographic and clinical predictors of perinatal outcome in full term neonates with hypoxic ischemic encephalopathy.Methods: Forty two neonates were diagnosed as cases of hypoxic ischemic encephalopathy by specialist pediatricians& admitted in Children Welfare Teaching Hospital & Al Kut Hospital in the period from January 2008 to March 2009. Predictors studied were sex, birth weight, Apgar scores at 1,5,15 min., meconium aspiration, lethargy, muscle tone , convulsion. Outcome was also recorded. Statistical analysis was done by the use of fisher exact test.Results:The total number studied were forty two neonate. Half of them were born at home & others in hospital with a male / female ratio= 1/1. Thirty three newborns had normal birth weight & nine had low birth weight. the mean apgar score recorded for sixteen neonate born in hospital at 1 minute = 4.3 ± 1.922, at 5minute=6.06± 2.08 and at 15 minute = 6.62± 2.33. out of the 21 hospital born babies with HIE, 6 died and 15 improved and out of 21 home born babies with HIE4 died and 17 improved. The difference was not statistically significant. P. value.0.7.Conclusion: Full term newborn babies with HIE died more frequently if they were males, with low birth weight, with Apgar scores of`< 4 at 1 min., 4-7 at 5 and 15 min., meconium aspiration, convulsion, hypotonic. Hypertonia and lethargy were noticed to be associated significantly with perinatal mortality in newborns with HIE

Keywords

Predictors --- HIE --- Fullterm Neonates


Article
Predictors and Frequency of Convulsions in Neonates with Neonatal Hypoglycemia; a Hospital-Based Study
تنبؤات و نسبة تكرار الاختلاجات في الاطفال حديثي الولادة المتلازمين بهبوط نسبة السكر في الدم; بحث اجري في المستشفى

Authors: Kawes O. H. Zangana د. كاويس عمر زنكنة --- Abdullah F. Ahmed عبد الله احمد
Journal: IRAQI JOURNALOF COMMUNITY MEDICINE المجلة العراقية لطب المجتمع ISSN: 16845382 Year: 2013 Volume: 26 Issue: 1 Pages: 24-29
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract

AbstractIntroduction: Transient low blood glucose levels are common in neonates as the source of glucose at delivery changes from a continuous supply from the mother to the intermittent supply from feeds. The overall incidence of hypoglycemia has been estimated at 1 to 5 per 1,000 live births, but it is higher in at-risk populations. Aim of study: To identify predictors, risk factors and frequency of convulsion in hypoglycemic neonatesPatients and methods: A cross sectional study of analytic purpose was performed on 186 hypoglycemic neonates admitted to the neonatal intensive care unit in Maternity Hospital and Raparin Pediatric Teaching Hospitals in the period from February1st 2010 to June 1st 2011 in Erbil governorate. Neonates presented with symptomatic hypoglycemia and blood glucose less than 30 mg/dl in the first day and less than 40mg/dl after first day were included in the study according to American Academy of Pediatrics criteria of neonatal hypoglycemia. The reading was taken while the neonate was just presented with the symptoms and had not received any glucose solutions.Results: Overall 4768 neonates admitted to the NICU during the study period; 186(3.9 %) developed hypoglycemia. 111(59.67%) of them were males and 75(40.33%) were female. Convulsions developed in 34(18.27%) of them; out of 34 convulsing hypoglycemic neonates, 20(58%) were males and 14(41%) were females with a male to female ratio of 1.42:1. Low birth weight hypoglycemic neonates more affected with convulsions 25(73.5%) versus normal birth weight neonates 9(26.7%). Premature babies also more affected with convulsions 20(58%) versus appropriate for gestational age babies 14(41.17%).Conclusions: Neonatal hypoglycemia is a common finding in neonatal care units and may lead to convulsions if not identified early and treated properly, and it’s more common in premature, small for gestational ages, infants of diabetic mother and mothers receiving glucose infusions before delivery, while jitteriness, lethargy and apnea were features that most commonly precede neonatal convulsion secondary to hypoglycemia Key words: neonates, premature, hypoglycemia, convulsions

الملخصالمقدمة: الهبوط المؤقت في نسبة السكر في الدم شائعة في الاطفال حديثي الولادة لان مصدر الكلوكوز اثناء الولادة يتغير من مصدر مستمر عن طريق الام الى تمويل متقطع من الرضاعة. ويقدر حالات هبوط نسبة السكر1 الى 5 من 1000 حالة ولادة حية لكن النسبة اعلى في حديثي الولادة المعرضين للخطر.الهدف من الدراسة: اكتشاف عوامل الخطورة و المنبئات ونسبة تكرار الاختلاجات لدى الاطفال حديثي الولادة المصابين بهبوط السكري المرضى وطرق البحث: اجري البحث على 186 طفل حديثي الولادة المصابين بهبوط السكري الذين ادخلو الى وحدة العناية لحديثي الولادة بمستشفى الامومة و مستشفى رابةرين التعليمي للاطفال في محافظة اربيل خلال فترة 1-2-2010 الى 1-6-2011 . ان الاطفال حديثى الولادة المصبون بهبوط نسبة السكري المتلازمة مع الاعراض و نسبة كلوكوز الدم اقل من 30 ملغ في الاول واقل من 40 ملغ بعد اليوم الاول ادخلوا في هذا البحث حسب معيير الاكاديمية الاميركية للاطفال المتعلق بهبوط السكري في الاطفال حديثي الولادة .اخذت القراءة في حالة حدوث الاعراض المذكورة قبل اعطاء اي محلول كلوكوز النتائج: ادخل 4768 حديثي الى وحدة العناية المركزة لحديثي الولادة اثناء فترة البحث. 186(3.9%) اصابوا بهبوط نسبة السكي .111( 59.67%) منهم كانوا ذكورا و 75(40.33%) كانوا اناثا. حصلت اختلاجات في 34(18.27%) منهم , من 34 حديثي الولادة المصبين باختلاجات بسبب هبوط السكري, 20 (58%) كانوا ذكورا و 14(41%) كانوا اناثا مع نسبة الذكور والاناث 1.42:1 .اصيب حديثي الولادة المصابين بهبوط السكري ذوي اوزان ولادية منخفضة باختلاجات بنسبة 25(73.5%) مقارنة بحديثي الولادة ذوي اوزان ولادية طبيعية, وكذلك اصابة اطفال الخدج بالاختلاجات كانت اكثر20(58%) مقارنة بالاطفال الكاملين في العمر اثناء الحمل 14(41.17%)الاستنتاجات: هبوط نسبة السكري في حديثي الولادة يعتبر شائعا في وحدات عناية حديثي الولادة و قد يؤدي الى الاختلاجات اذا لم اكتشافها مبكرا و علاجها بطريقة سليمة و يعتبر اكثر شيوعا في الاطفال الخدج و الاطفال دون الوزن الطبيعي, الاطفال المولودون لدى امهات يعانون من داء السكري و الامهات اللاتى اعطين محلول الكلوكوز قبل الولادة . التهيج و السبات و انقطاع النفس يعتبر من الاعراض الاكثر شيوعا قبل حدوث الاختلاجات المصابين بهبوط نسبة السكري.


Article
Neonatal Polycythemia: Risk Factors, Clinical Manifestation and Treatment Applied

Authors: Sawsan Sati Abbas --- Hamed Fakhri Fayadh
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2013 Volume: 12 Issue: 3 Pages: 390-395
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

BACKGROUND: Polycythemia is defined as a venous hematocrit above 65%.Polycythemia is sometimes associatedwith hyper viscosity of blood .The etiology of polycythemia is related either to intra-uterine hypoxiaor secondary to fetal transfusion. Increased viscosity of blood is associated with symptoms of hypoperfusion.Clinicalfeaturesrelatedtohyperviscositymayaffectallorgansystems. OBJECTIVE: To evaluate the prevalence of polycythemia among neonates who were admitted to the nursery careunit, to evaluate the difference between peripheral and central hematocrit (PCV) and to have an ideaabout the main presentation and modes of treatment of polycythemia. PATIENTS AND METHODS: A case – control study was done in the nursery care unit of AL - Kadhyimia Teaching Hospital , onehundred neonates (50 polycythemic and 50 control healthy neonates ) were taken , for each neonates ,information regarding (name ,age , sex , gestational age , mode of delivery , body weight ,length, headcircumference , clinical presentation and risk factors ) were taken, investigations includinghematocrite (PCV) , random blood sugar and total serum bilirubin were done for all neonates. RESULTS: The prevalence of neonatal polycythemia was (2.2%) , male was affected more than female with male: female ratio equal to ( 1.5:1) . The difference between peripheral and central PCV was (4 - 15%) with a mean and standard deviation of ( 7 ± 0.33%). The main signs & symptoms were jaundice (58%), lethargy (30%) , respiratory distress(26%) and hypoglycemia (26%) . Risk factors were preterm (36%) , neonates of diabetic mother(20%) , small for gestational age (18%) , twin pregnancy (12%) and down's syndrome (10%) . Partialexchange transfusion was done to 28 cases (56%). CONCLUSION: Males were affected more than females. Jaundice was the main presentation followed by lethargy,respiratory distress and hypoglycemia .Higher risk in twin pregnancy ,neonates of diabetic mother ,small for gestational age , preterm and down's syndrome while delivery by caesarian section reducethe risk of polycythemi


Article
Analytic Study Of Congenital Malformations In Four

Author: Numan Nafie Hameed
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2007 Volume: 49 Issue: 1 Pages: 32-36
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Congenital malformations are responsible for a considerable proportion ofperinatal, neonatal and infant mortality in many Eastern Mediterranean countries. So this studyaims to find out the incidence, types and probable risk factors of these malformations in Baghdad.Patients and methods: one hundred cases of congenital malformations were studied out of 8090neonates born in 4 hospitals in Baghdad province over 5 months in 2002 (preterm, term) .Theincidence , types and risk factors were analysed .Results: the incidence of congenital malformations was 12.36/ 1000 live births, with the centralnervous system malformations being the commonest. There is increased risk in consanguinousmarriages 27 (27%), mothers not attending antenatal care 25 (25%), mothers of low gravidity 60(60%), and mothers not taking folic acid during pregnancy (86.7%).Conclusion: Consanguineous marriages and mothers not taking folic acid during pregnancy areimportant risk factors for the occurrence of congenital malformations .So I recommend geneticcounseling especially for consanguineous marriages, and giving all pregnant women folic acidbefore and during pregnancy. A multicentre study will give more broad idea about the incidence ,types ,and risk factors in our country


Article
HUMAN CYTOMEGALOVIRUS INFECTION AMONG NEONATES WITH SYMPTOMATIC CONGENITAL INFECTIONS AND BIRTH DEFECTS

Loading...
Loading...
Abstract

Background:Human cytomegalovirus (HCMV) is the major viral etiology of congenital infection and birth defects, during current maternal infection the fetal transmission is high (30-40%) and the symptomatic neonates have diseases involving the neurologic, hematopoietic, respiratory and other organ systems, causing high mortality and long-term sequelae.Objective:To measure the frequency of congenital and perinatal HCMV infection among symptomatic neonates and its possible burden of disease among them.Methods:A total of one hundred ninety-eight symptomatic neonates with clinical manifestations of overt congenital infection enrolled in this study from September 2014 to March 2015. Serum samples were obtained from each subject targeted in this study. HCMV infection was defined as HCMV-IgM antibody positive by Electrochemiluminescence Immunoassay (ECLIA) techniques. Results:The prevalence of HCMV infection among symptomatic neonates with congenital infection was 25 (12.6%). The average age of HCMV detection was 9.96 (SD 6.73) days with a median of 7 days, a minimum of 3 days and a maximum of 28 days. Jaundice was the most predominant clinical finding 14 (56%), followed in order of frequency by hepatomegaly 9 (36%) and pneumonitis 7 (28%).Conclusion:The high prevalence of neonatal HCMV infection among neonates with symptomatic congenital infections could indicate a high rate of maternal HCMV primary or current infection among our population.Keywords: HCMV, congenital infection, neonates, clinical finding.


Article
The Effect of Birth Asphyxia on the Coagulation Status in Neonates

Authors: Ashwaq Ali Hussein --- Hithab Jawad Muhsen --- Rajaa Jabbar Kadhum
Journal: Karbala Journal of Medicine مجلة كربلاء الطبية ISSN: 19905483 Year: 2017 Volume: 10 Issue: 2 Pages: 2719-2724
Publisher: Kerbala University جامعة كربلاء

Loading...
Loading...
Abstract

background: Birth asphyxia has multi system effect, which predisposes to coagulopathy by enhancing consumption of platelets & some clotting factors as a results of the associated sever hypoxemia, acidaemia & sepsisObjective: To study the effects of birth asphyxia & perinatal events on the coagulation status of newborn infants. Patients & Methods: Across sectional study was done on 27 neonates with birth asphyxia in AL-Zahraa teaching hospital in Najaf city from period of first of February 2012 to first of July 2012. Blood samples were collected from the neonates within the first 24 hrs. After birth and sent for investigations including PT, PTT, plasma fibrinogen and platelet count.Results: The study showed statistically significant effect of birth asphyxia on platelet count especially in severely asphyxiated neonates with Apgar score of 0 – 3 at 5 min after birth (plat. Count < 100,000 per mm3) in comparison to neonates with Apgar score of 4 – 6 at 5min after birth. Infants who have very low birth wt. (i.e. <1500 gms) had significantly lower platelet count (< 100,000 per mm3) than infants with birth wt.>1500 gmsBirth asphyxia had no significant effect on PT, PTT, or fibrinogen level. Other perinatal and prenatal variables examined as (sex, maternal hypertension, DM, mode of delivery gestational age) did not show any significant association with coagulation status.Conclusion: Thrombocytopenia (plat. <100.000 per mm3) is seen in neonates with Apger score (0-3) at 5 min. and in neonates with very low birth wt. <1500gms). No statistically significant relation between birth asphyxia and PT, PTT and plasma fibrinogen level.


Article
Early Outcome of Surgical Intervention of Esophageal Atresia and Tracheo‑esophageal Fistula in Erbil Pediatric Surgical Center

Author: Najat Abdulkadr Hamad, Hawkar Abdullah Kak‑Ahmed1, Nooraddin Ismail Allaquli
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2018 Volume: 15 Issue: 2 Pages: 129-134
Publisher: Babylon University جامعة بابل

Loading...
Loading...
Abstract

Background: Esophageal atresia (EA) and treacheo-esophageal fistula occur in 1 out of every 3500 live births. Children born with EA have ahigher incidence of prematurity than the general population EA. The treatment of EA and tracheo-esophageal fistula, although still a challenge,represents one of the true successes of newborn surgery. Objective: The aim of this study cases with EA and/or tracheo-esophageal fistula inRapareen pediatric surgery center, Erbil, Iraq, regarding management, and early outcome. Materials and Methods: Fifty-three neonates wereenrolled in this study from October 2011 to September 2015. Preoperative investigations included chest X-ray, ultrasound of the abdomen,and echocardiography. All patients were resuscitated before surgical intervention. Statistical Package for the Social Sciences version 20 wasused for data analysis. Results: Out of 53 cases, 21 survived and 32 died. Thirty patients were male and 23 were female (male-to-female ratio1.3:1). Twelve were premature and 41 term babies. The most common type was EA and distal fistula in 47 cases, pure atresia in 5 cases, andEA with both distal and proximal fistula in one case. Presenting features were excessive salivation in all cases, failure to pass nasogastric tubein 98.1%, cyanosis in 69.8%, and chocking in 37.7%. Prenatal history of polyhydramnios was present in 67.9%. Eighteen cases had associatedanomalies, most of them were cardiac. Conclusion: EA with distal tracheo-esophageal fistula is the most common type of anomaly. Earlydiagnosis, weight, maturity, and associated anomalies are the most important factors that affect the outcome. Postoperative respiratory care isnecessary, especially for those who have a preoperative chest infection.


Article
The effect of atropine on heart rate with rapid sequence induction in neonates

Author: Ahmed Haki Ismael Al-Rawee
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2012 Volume: 11 Issue: 2 Pages: 53-57
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract

Background: neonates experience physiological responses toendotracheal intubation, including bradycardia and oxygen desaturation.The bradycardia may be associated with severe hemodynamicdisturbances like significant hypotension which may threaten patient'ssafety.Aims: To determine the effectiveness of single dose IV atropine, 5minutes before induction of anesthesia on reflex bradycardia tolaryngoscopy in sick neonate baby.Patients and Methods: In a randomized double blinded, placebocontrolled clinical trial, thirty neonates aged 1-10 days, term, 2.5-3.5kgand from both sexes, were enrolled to receive 0.02mg/kg IV atropine(n=15), as study group and placebo group had received equivalentvolume of normal saline five minutes before induction of anaesthesia(n=15), as control group. The induction technique was the same in allpatients. The incidence of bradycardia just after intubation wasrecorded.Results: data analyses showed that the overall incidence of bradycardiajust after intubation in the study group was significantly lower than thecontrol group.Conclusions: A single dose IV atropine five minutes before induction ofanaesthesia in neonate baby significantly decreases the incidence ofbradycardia after intubation.


Article
Identification of bacterial agentsand antimicrobial susceptibility of neonatal sepsis with patient,s outcome

Authors: Abdul-Kareem Mohammed Ali عبد الكريم محمد --- Lamia Abdul-Kareem لمى عبد الكريم --- Emad Japur Rashed عماد جبر رشيد
Journal: Al-Qadisiyah Medical Journal مجلة القادسية الطبية ISSN: 18170153 Year: 2014 Volume: 10 Issue: 17 Pages: 148-161
Publisher: Al-Qadisiyah University جامعة القادسية

Loading...
Loading...
Abstract

Background : Sepsis neonataroum is an important factor for morbidity and mortality in neonates. The incidence of neonatal bacterial sepsis depends on geographic area and may vary from country to country as well as within the same country. Objective: To identify the percentage of neonatal septicemia confirmed by positive blood cultures among 664 neonates admitted in neonatal care unit, and to identify the bacterial agents causing early and late neonatal sepsis and their antimicrobial susceptibility, and the outcome from neonatal septicemia. Patients and methods: The total number of patients(with clinical signs and symptoms suggesting sepsis) collected from neonatal care unit of AL-Kadimiya Teaching hospital from the 1st of January to the end of october 2011 were 664 neonates, and only 105 neonates who show signs and symptoms suggestive of septicemia that were confirmed by a positive blood culture were enrolled in this study. Data were collected include :Gestational age, Birth weight , Gender, Onset of sepsis, Place of delivery and also we followed up the subjects and recorded the outcome till discharge. Results: In this prospective study and from 664 neonate were admitted (total number of admission), positive blood cultures were obtained for 105 neonates (15.8%). Gram negative bacteria were the commonest causative agent in both early (66.7%) and late (56.9%) onset sepsis. Among neonates with sepsis, 33 patients (31.4%) had early onset and 72 patient (68.6%) had late-onset neonatal sepsis. The susceptibility of the isolated causative agent to selected antibiotics were the same in early and late onset sepsis. Over 70% of gram negative bacilli were resistant to both ampicillin and cloxacillin but show variable sensitivity to gentamicine and cefotaxime. Most of the isolated gram positive bacteria were sensitive to ampicillin, cloxacillin and cefotaxime but highly resistant to gentamicin. The death rate was 20.9%. Early onset sepsis, male gender, gestational age less than 37 weeks and birth weight less than 2500 gm were found to be significantly associated with death. Conclusions: Gram negative bacteria were the main cause of early and late-onset neonatal sepsis in our center and many of these isolated bacteria were resistant to the used antibiotics. Low birth weight neonates <2500 gm, gestational age < 37weeks, male gender and early onset sepsis were significantly associated with death. The death rate due to neonatal sepsis was higher compared with the other studies. Recommendations: Proper antenatal care and optimal obstetric management in early detection and treatment of mothers at risks together with minimizing invasive procedures of infants as much as possible and ideal nursery setup which includes adequate space for care of infants and aseptic equipments for monitoring.

العفن الولادي هو سبب مهم من أسباب الوفيات للأطفال حديثي الولاده.أن نسبة حدوث العفن الولادي البكتيري تعتمد على المنطقه الجغرافيه وقد تختلف من بلد ألى بلد وأيظا في البلد الواحد.الهدف من الدراسه لمعرفة نسبة حدوث العفن الولادي , البكتيريا المسببه للعفن الولادي المبكر والمسببه للعفن الولادي المتأخر وأيضا معرفة مدى أستجابتها للمظادات الحيويه ومعرفة نسبة حدوث الوفيات الناتجه من العفن الولادي في وحدة حديثي الولاده. لقد تم جمع المرضى من وحده حديثي الولاده في مستشفى الكاظميه التعليمي للفتره من الاول من كانون الثاني الى نهاية تشرين الاول لسنة 2011 م. كل المرضى الدين أدخلوا الى وحدة حديثي الولاده والذين لديهم العلامات والاعراض التي تدل على العفن الولادي والتي تم تأكيدها بواسطة زرع الدم الموجب تم أدراجها في هده الدراسه. المعلومات التي جمعت تشمل:عمر الجنين عند الولاده , الوزن عند الولاده , جنس المولود , تأريخ حدوث العفن الولادي , مكان الولاده , وكدلك تم متابعة المرضى وتسجيل النتيجه النهائيه للمرض. في هذه الدراسه ومن 664 مريض تم أدخالهم, كانت نتيجة زرع الدم موجبه ل105 حاله (15,8%). البكتيريا السالبه لصبغة الكرام كانت اكثر انواع البكتيريا المسببه لكل من العفن الولادي المبكر(66,7%) والعفن الولادي المتأخر(56,9%). أن من بين هؤلاء المرضى كانت هناك 33 حاله (31,4%) من عفن الدم المبكر و 72 حاله (68,6%) من عفن الدم المتاخر. أن استجابة البكتيريا للمضادات الحيويه التي جربت كانت متشابهه في حالتي العفن المبكر والعفن المتأخر في هذه الدراسه. أن أكثر من 70% من البكتيريا السالبه لصبغة الكرام كانت مقاومه لكل من الامبسيلين والكلوكساسيلين ولكن اظهرت استجابات متفاوته لكل من الجينتامايسين والسيفوتاكسايم. أن معظم البكتيريا الموجبه لصبغة الكرام اظهرت استجابه لكل من الامبيسيلين والكلوكساسيلين والسيفوتاكسايم بينما اظهرت مقاومه عاليه للجينتامايسين. أن نسبة الوفيات كانت 20,9%. أن العفن المبكر, الذكور, الولاده المبكره الاقل من 37 اسبوع و الوزن الاقل من 2500غرام عند الولاده كانت عوامل مصاحبه للوفاة . البكتيريا السالبه لصبغة الكرام كانت السبب الرئيسي للعفن الولادي المبكر والمتاخر في مركزنا وان العديد من البكتيريا المسببه كانت مقاومه للمظادات الحيويه المستخدمه. نوصي بالعنايه الجيده خلال اللحظات الاولى للولاده والمتابعه الافضل اثناء التداخلات الولاديه والكشف المبكر والعلاج اللازم للأم المصابه بالألتهابات مع تقليل التداخلات الجراحيه المساعده للولاده قدر المستطاع مع مراعاة ترك مسافات مناسبه بين الاطفال الحديثي الولادة واستخدام الادوات المعقمه عند المراقبه


Article
Types ,Frequency,Clinical Presentation of Congenital Central Nervous System Anomalies in Al- Kadmayhia Teaching Hospital

Author: Lamyaa Abdul Kareem Hamoodi
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2014 Volume: 13 Issue: 4 Pages: 524-531
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

ABSTRACT:BACKGROUND:The central nervous system (CNS)anomalies are the most severe, difficult to detect its etiology, and predict its clinical presentation and course. OBJECTIVE:To find out the common types of congenital malformations in central nervous system.,determine the frequency and the clinical features of these malformations.And to study the risk factors associated with congenital central nervous system malformations.PATIENTS AND METHODS:This cross-sectional study was performed at Al-Kadhimiyia Teaching Hospital (Neonatal care unit) from the 1st of January to the 1st of July, 2011.One hundred newborn infants were proved to have congenital abnormalities by physical examination alone. Fifty five neonates were diagnosed as having CNS congenital anomalies.neonatal evaluation include: gestational age, sex, body weight, type of CNS congenital anomaly.Maternal age, parity, antenatal care, any history of abortion, previous baby with CNS congenital abnormality, still births, or drug intake during pregnancy.the residency of the family and consanguinity .RESULTS:The number of neonates delivered alive was 2700 neonates, one hundred of them (3.7% of total deliveries) were delivered with congenital anomalies, and 55 cases from those (2% from total deliveries / 55% from congenitally abnormal deliveries) have had CNS congenital anomalies,the most frequent anomalies aremeningocele 25( 45.5%),the second and third in frequency were hydrocephaly 12 (21.8%), and myelomeningocele 10 (18.2%) respectively.There were 34(61.8%) male and 21 (38.2%) female. There were 30(54.5%) full term and 25(45.5%) preterm.Thirty cases out of the total 55 cases (54.5%) with body weight 3-3.5 kg.Most of the affected neonates to mothers with an age range of 20-40 years where 34 mothers (61.8%) aged between 20-30 years .Most of the mothers were multipara (45 cases / 81.8%) .The majority of the neonates were the product of a consanguineous marriage 39 (70.9%).Maternal peri-conceptional folic acid supplementation was not taken in the vast majority of cases (43 cases / 78.2%).Positive family history of CNS congenital anomalies was reported in 4 cases only (7.3%) .Familial residence was documented as urban in 30 cases (54.5%), and rural in 25 cases (45.5%).CONCLUSION:The most common type of CNS anomalies is meningocele with relatively higher male to female ratio.These anomalies occur in full term multipara mothers. Occur more frequent in infants with larger body weight and to younger multipara mothers. Consanguinity is a major risk. There was a low utilization of maternal peri-conceptional folic acid supplementation

Listing 1 - 10 of 19 << page
of 2
>>
Sort by
Narrow your search

Resource type

article (19)


Language

English (15)

Arabic and English (3)


Year
From To Submit

2019 (1)

2018 (2)

2017 (1)

2016 (2)

2015 (1)

More...