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The aim of this study was to evaluate the clinical utility, safety and outcomes of semi-rigid ureteroscopy in the treatment of single renal pelvic stones by using Holmium: YAG laser lithotripsy.Hundred patients (56 females, 44 males), aged between (11) and (67) years (mean 41.5 years), with single renal pelvic stone range from 13-27 millimeter (mean size 21.8 millimeter). Inclusion criteria (any patient with single renal pelvic stone less than 30 millimeter in size regardless its composition and previous history of any urological intervention and the stone is visualized by uretroscope), treated with semi-rigid ureteroscopy by using Holmium: YAG laser for stones pulverization. DJ-stent had been inserted to all patients following stone fragmentation. Preoperative data, as well as stone free rate, operative time and associated perioperative complications were evaluated.The primary stone free rate (which was assessed by Ultrasonography and plain abdominal X-ray) was sixty-eight percent (68 patients) at the first postoperative day, which increased to eighty-six percent (86 patients) after one month by using ancillary procedures such as Extra Corporeal Shock Wave Lithotripsy and medical treatment. the operative time was ranges from 44.3 to 97.8 minute (mean of 72.4 minute), there was no major perioperative complications.The study can conclude that Reterograde semi-rigid ureteroscopy using holmium: YAG Laser is effective and safe option for managing single renal pelvic stone less than 27 mm.

Semi-rigid ureteroscopy --- retrograde renal surgery --- renal pelvic stone --- Ho --- YAG laser.