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COMBINATION OF ROCURONIUM WITH PROPOFOL TO AID ENDOTRACHEAL INTUBATION IN EMERGNCY CESAREAN SECTION

Authors: Edwar Z Khosho --- Mohammad Radhi Al-Rekaby
Journal: Basrah Journal of Surgery مجلة البصرة الجراحية ISSN: 16833589 / ONLINE 2409501X Year: 2015 Volume: 21 Issue: 2 Pages: 55-60
Publisher: Basrah University جامعة البصرة

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Abstract

Abstract This study aimed to verify that rocuronium can be used as an alternative to succinylcholine for rapid sequence intubation in emergency cesarean section. A study conducted on 300 ladies in Al-Basrah Maternity and Childbirth Hospital between February 2013 to November 2014. Assessment of the effectiveness of rocuronium 0.6 mg/kg with propofol as an intubating dose for emergency caesarean section. The intubation conditions of rocuronium was compared with succinylcholine 1mg/kg as standard muscle relaxant of choice. Rocuronium 0.6 mg/kg with propofol resulted in 94% clinically acceptable (good to excellent) intubation conditions but for succinylcholine it was 95-97%. In conclusion, although succinylcholine creates excellent intubation conditions in emergency caesarean section, rocuronium proved its efficacy as a good alternative choice for succinylcholine.


Article
Rapid Sequence Induction using Rocuronium in Adult Patients

Author: Hasan Sarhan*, Ahmed Saeed Abdullah**, Ahmed Mohammed Hussein***
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2016 Volume: 15 Issue: 4 Pages: 429-436
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND: Several studies using rocuronium as an alternative to suxamethonium for endotracheal intubating conditions in rapid sequence induction are available in literature, all claiming obvious advantages, but intubating conditions after suxamethonium and rocuronium have not been assessed in our hospitals yet.OBJECTIVE: The aim of this study was to assess the efficacy of rocuronium for rapid sequence induction by comparing the endotracheal intubating conditions with suxamethonium, following induction with sodium thiopentone as the sole induction agent in elective, otherwise healthy, adult patients.MATERIALS AND METHODS:The patients were divided into two groups, each consisting of 40 patients: group A patients received rocuronium bromide 0.6 mg/kg IV, and group B patients received suxamethonium chloride 1.5 mg/kg IV. In both groups, jaw relaxation and vocal cord relaxation were considered for atraumatic laryngoscopy at 60 seconds . Induction of anesthesia achieved with thiopentone as a sleeping dose for all patients.RESULTS: All the patients in the suxamethonium group have excellent intubating conditions, while in the rocuronium group, 90% of the patients were excellent and 10% were good regarding the intubating conditions. CONCLUSION: It is concluded from this study that intubation can be performed under good to excellent conditions at 60 seconds after a bolus dose of rocuronium of 0.6 mg/kg. The result of this study indicates that this nondepolarizing neuromuscular blocking agent may be considered as a valuable alternative to suxamethonium for rapid sequence induction, i.e., within 60 seconds, even after induction with thiopentone as the sole anesthetic agent.

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