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تأثير بيرو كسيد الهيدروجين والكلور كقاتلات للرؤيسات الاولية للمشوكة الحبيبية Echiococcus granulosus خارج الجسم الحي

Author: Buthaina Hatim Hashim Al-Sabawi بثينة حاتم هاشم السبعاوي
Journal: Tikrit Journal of Pure Science مجلة تكريت للعلوم الصرفة ISSN: 18131662 Year: 2008 Volume: 13 Issue: 3 Pages: 241-247
Publisher: Tikrit University جامعة تكريت

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Abstract

The present study was conducted to determine the effect of hydrogen peroxide at concentrations of 1, 10 and 15% and chlor at concentrations of 0.5 and 1% on the viability of protoscoleses of Echinocossus granulosus in vitro.Protoscoleces were incubated at the above mentioned concentrations for 5, 10 and 15 minutes. Physiological normal saline alone used as a control group.Results, revealed, a significant decrease in the viability of protoscoleces treated with different concentrations of hydrogen peroxide and chlor at different periods. The decrease was proportional with the concentration and the period of exposure. Best result was obtained at 15% hydrogen peroxide for 15 minutes as 99% of the protoscoleses were damaged.Histological sections revealed, great changes on protoscoleces treated with the above mentioned concentrations of hydrogen peroxide and chlor, including destruction of tegument, rostellar disorganization, loss of hooks, compared with the control group.

اجريت الدراسة الحالية بهدف تحديد تاثير كل من بيروكسيد الهيدروجين بالتراكيز 1 ، 10 و15% والكلور بالتركيزين 0.5 و1% في حيوية الرؤيسات الاولية للمشوكة الحبيبية خارج الجسم الحي.حضنت الرؤيسات الاولية بالتراكيز المشار اليها وللفترات 5، 10 و15 دقيقة. استخدم المحلول الملحي الفسلجي لوحده كمجموعة ضبط.اظهرت النتائج انخفاظا معنويا في حيوية الرؤيسات الاولية المعاملة بالتراكيز المختلفة من بيروكسيد الهيدروجين والكلور وللفترات المختلفة، وتناسب الانخفاض طرديا مع التركيز والفترة الزمنية للتعريض. افضل نتيجة كانت عند استخدام بيروكسيد الهيدروجين بتركيز 15% ولمدة 15 دقيقة اذ وصلت نسبة تحطيم الرؤيسات الاولية الى 99%.اظهرت المقاطع النسجية وجود تغيرات كثيرة في الرؤيسات الاولية المعاملة بالتراكيز المشار اليها لكل من بيروكسيد الهيدروجين والكلور وشملت هذه التغيرات، تحطم واضح في الجليد ، فقدان تنظيم الخطم وفقدان الاشواك مقارنة مع مجموعة السيطرة.


Article
Percutaneous Treatment of Liver Hydatid Disease, Clinical Experience with 22 Patients

Author: Ibrahim Falih Noori
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2016 Volume: 13 Issue: 2 Pages: 522 -530
Publisher: Babylon University جامعة بابل

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Abstract

The purpose of this study was to assess the efficacy and validity of the puncture-aspiration –injection and re-aspiration (PAIR)and catheterization in the percutaneous treatment of hydatid cyst disease of the liver. This is aprospective study that had been performed in a major hospital in Basra city, Iraq for the period between April 2010 and May 2014 in which 22 patients with a diagnosis of hydatid cystic disease of liver subjected to a percutaneous treatment using PAIR technique or catheterization method under ultrasonographic guidance and under cover of albandazol or mebandazol before and after intervention .Following aspiration of the cystic fluid ,hypertonic saline 20% was injected into the cystic cavity and re-aspirated .Subsequent follow up and observation was carried out by ultrasonic examination to assess the efficacy and of this approach.Twenty four cyst (72.7%) in this study was GharbiIcyst, 4 patients (18%) had type II and 2 patients only had type III. The mean reduction in the volume of the cyst after 9-12 months follow up period was 92.6% and 87.5% in catheterization and PAIR method respectively .All patients were in very good condition. Liver and blood tests were normal after intervention. Solidification and pseudotumor was seen in 18 patients (81.8 %) and calcification was seen in 12 patients (54.5%).The mean hospitalization time was 3 days. Percutaneous treatment for selected patients with type I –III Gharbi hydatid liver cyst is effective and safe procedure .It offers complete cure with infrequent complications and short hospitalization. Surgery however, remains the gold standard treatment for multivesicular, infected and complicated cases of hepatic liver cysts.

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