research centers


Search results: Found 10

Listing 1 - 10 of 10
Sort by

Article
An Echocardiographic Study of Valvular Heart Disease Associated with Systemic Lupus Erythematosus

Author: Safa Ez-Aldeen Al-Mukhtar
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2006 Volume: 5 Issue: 4 Pages: 396-405
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

ABSTRACT:BACKGROUND:Valvular heart disease is the most important cardiacmanifestation of systemic lupus erythematosus (SLE). We performed a study to determine the relation of valvular disease to other clinical features of lupus, the type and the incidence of valvular heart disease in SLE patients.METHODS:We performed transthoracic echocardiography (TTE) and rheumatologic evaluations in 56 patients with systemic lupus erythematosus. The echocardiographic findings were compared with those in 40 healthy volunteers.RESULT:Abnormal valvular Echocardiographic findings were multiple valvular abnormalities found in 21 patients (37.5%), were distributed in three groups according of valvular involvement: (Group1) included patients with anatomical and functional valvular involvement (AFVI) in seven patients (12.5%). (Group2) included patients with anatomical valvular involvement without Doppler detected valve dysfunction (AVI) in 11 patients (19.6%). (Group3) included patients with functional abnormalities (stenosis or regurgitation) without valvular thickening (FVI) in three patients (5.3%). Positive antiphospholipids antibody (aPLs) was found in a total of 29 patients (51.7%), of those 17 patients (58.6%) had valvular echocardiographic abnormalities and four patients (14.8%) of the 27 patients with negative aPLs had abnormal echocardiographic findings.CONCLUSIONS:Valvular heart disease is common in patients with SLE, valvular abnormalities were correlated with the aPLs in patients with SLE. Echocardiography is an excellent tool for the diagnosis and follows up of valvular abnormalities in patients with SLE.


Article
The Association Of Autoimmune Thyroiditis With Systemic Lupus Erythematosus
العلاقة بين التهاب الغدة المناعي مع داء الذؤابة الأحمراري

Author: Wesal Salman Abdulmuhsin وصال سلمان عبدالمحسن
Journal: Thi-Qar Medical Journal مجلة ذي قار الطبية ISSN: 19929218 Year: 2010 Volume: 4 Issue: 2 Pages: 53-58
Publisher: Thi-Qar University جامعة ذي قار

Loading...
Loading...
Abstract

ABSTRACT: We determined the degree of ovelap between autoimmune thyroiditis disease and Systemic Lupus Erythematosis (SLE). Fourty one SLE patients with twenty age- and sex-matched controls were included in this study. Twenty-one (51%) of the SLE patients had anti thyroglobulin (anti-TG) antibodies. Ten SLE patients had elevated TSH levels, usually in association with the presence of anti-TG. These results suggest that SLE is associated with autoimmune thyroiditis and that many patients with SLE have minor hypothyroidism.

الخلاصة: حددت درجة التداخل بين التهاب الغدة المناعي مع داء الذؤابة الأحمراري تضمنت الدراسة 41 مريضامصابا بداء الذؤابة الأحمراري مقارنة بمجموعة سيطرة .كان (51%) 21 منهم يحملون مضاد الثايروكلوبيولين وكان لعشرة مستويات عالية من الهرمون المحفز للدرقية مع حملهم لمضاد الثايروكلوبيولين . من هذه النتائج يتبين وجود علاقة بين التهاب الغدة المناعي مع داء الذؤابة الأحمراري حيث ان العديد من مرضى داء الذؤابة الأحمراري يعانون من انخفاض طفيف بأفراز الغدة الدرقية.


Article
Association of Autoimmune Thyroiditis and Systemic Lupus Erythematosus

Author: Wisal Salman Abd
Journal: Al-Nahrain Journal of Science مجلة النهرين للعلوم ISSN: (print)26635453,(online)26635461 Year: 2012 Volume: 15 Issue: 4 Pages: 179-182
Publisher: Al-Nahrain University جامعة النهرين

Loading...
Loading...
Abstract

This study was designed to investigate the relationship between Systemic Lupus Erythematosus (SLE) and autoimmune thyroiditis disease. Forty one SLE patients diagnosed by latex agglutination test with twenty age and sex matched controls were included in this study. Results revealed that twenty one (51%) of SLE patients had antithyroglobuline antibody and ten of the SLE had elevated TSH. These results suggests that there was an association between SLE and autoimmune thyroiditis

صممت هذه الدراسة للتحري عن العلاقة بين التهاب الغدة المناعي مع داء الذؤابة الأحمراري.تضمنت الدراسة 41 مريضا مصابا بداء الذؤابة الأحمراري مقارنة بمجموعة سيطرة.أظهرت النتائج 21 مريضاً (51%) منهم يحملون ضد الثايروكلوبيولين وكان لعشرة مستويات عالية من الهرمون المحفز للدرقية مع حملهم لمضاد الثايروكلوبيولين.هذه النتائج تبين وجود علاقة بين التهاب الغدة المناعي مع داء الذؤابة الأحمراري.


Article
Oral manifestations, oral health status and saliva composition changes in a sample of Iraqi systemic lupus erythematosus patients

Authors: Noor S. Mohammed نور محمد --- Taghreed F. Zaidan تغريد زيدان
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2012 Volume: 24 Issue: special issue 2 Pages: 65-69
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease associated with significantmorbidity and mortality. Sicca symptoms are frequent in SLE which may be related to concomitant occurrence ofSjögren's syndrome (SS). The aims of study were to determine prevalence of oral manifestations andtempromandibular joint disorders, and to find a correlation between the changes in saliva flow rate, pH andcomposition with the incidence of dental caries in SLE patients.Subjects, materials and methods: One hundred and two individuals were enrolled in this study; 52 of them were SLEpatients; and 50 were healthy control individuals matched in age and gender. The assessment of dental status wasmade according to the decay missing filling teeth (DMFT) index; the gingival inflammation was assessed using thecriteria of gingival index; Clinical pocket depth was measured with periodontal probe type William, and wholeunstimulated saliva samples have been collected from each subject for biochemical analysis. Also, salivary flow rateand pH were measured. After centrifugation, the supernatant of saliva was aspirated for biochemical analysis.Results: Oral ulceration was the most prominent orofacial manifestations of SLE patients followed byTempromandibular joint (TMJ) disorders and facial skin rash then oral vesicles& bullae, oral lichen planus and finallyoral petechiae & purpura. Salivary flow rate and salivary pH were significantly lower in SLE patients than in the controlsubjects. Oral hygiene index (DMFT index, gingival index, Clinical pocket depth) were significantly higher in SLEpatients than in the control subjects .Salivary calcium, sodium, chloride, and total protein were significantly higheramong SLE patients than in the control subjects. While salivary potassium and inorganic phosphorus were significantlylower among SLE patients than in the control subjects. In addition, there was a highly significant positive linearcorrelation between age of SLE patients and DMFT, and between age and clinical pocket depth; and a highlysignificant negative linear correlation between salivary flow rate and salivary calcium in SLE patients. Also there washighly significant positive linear correlation between DMFT and salivary calcium, and between DMFT and salivarychloride.Conclusions: Oral manifestations are common in Iraqi SLE patients. Changes in salivary flow rate, pH, salivarycomposition, and increased dental caries may serve as potential markers of the extent of autoimmune mediatedsalivary gland dysfunction which is similar to Sjogren’s syndrome


Article
Correlation between Interleukin-4 and Interleukin-6 and auto antibodies in Systemic Lupus Erythematosus.

Author: Sajid N. Abdualkader* MBChB د. ساجد نادر عبد القادر
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2009 Volume: 51 Issue: 4 Pages: 416-418
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Summary:Background: There is a general acceptance which illustrated that auto antibodies act as a central immunological disturbance in most of the auto immune diseases, among these auto immune disease lies the SLEPatients and Methods: Thirty five patients with SLE were compared to twenty age and sex matched, control subjects and studied for the presence of auto antibodies, plus IL-4 and IL-6 using Elisa method and immune fluorescent method (for ANA only)Results: Data showed that IL-6 detectable levels were statistically significant in patients with positive anti ds-DNA, but not significant statistically in ANA positive patients although it was detected in 24 (70.6%) of positive ANA patients, while there was no statistically significant correlation between IL-4 detectable level and autoantibodies production.Conclusion: There is apparently a positive correlation between IL-6 and anti ds DNA production in lupus patients.Key words: Autoantibodies, Interleukin-4, Interleukin-6, systemic lupus erythematosus


Article
Human Leukocyte Antigens Assosiation with Systemic Lupus Arythematosus In Iraqi Patients

Loading...
Loading...
Abstract

Background: The etiology of Systemic lupus erythematosus seems to be multifactorial including environmental as well as genetic factors. The genetic predisposition was supported by the occurrence of Systemic lupus erythematosus in more than one member of a family as well as in identical twins.Aim of the study: To determine the human leukocyte antigen typing class I (A and B) in patients with Systemic Lupus Erythematousus disease. Methods: Patients group consisted of 44 Iraqi Arab Muslims patients with Systemic lupus erythematosus disease who presented to Baghdad Medical City from January 2010 to January 2012 from Baghdad Province. The second control group consisted from 80 Iraqi Arab Muslims volunteers from hospital employees and their relatives. Human leukocyte antigen typing done for them using serological method by microlymphocytotoxicity test.Results: A total of 44 patients with Systemic lupus erythematosus were studied. Patients' age ranged from 6 to 65 years with a mean of 29.61 ± 12.78. The other control group, their ages ranged from 16 to 55 years with a mean of 31.35 ± 10.02 . Females were more than males in both groups. Human leukocyte antigen typing of Systemic lupus erythematosus patients showed A2( 16, 36.36, 0.20), A3( 14, 31.82, 0.17), B4(10, 22.73, 0.12) , B12 (10, 22.73, 0.12) and B21(10, 22.73, 0.12) were the highest absolute numbers, phenotype frequencies and genotype frequencies respectively. There was a significant difference in between SLE patients and control group in the following alleles (A1, A28, A36, A43,B 6, B12, B14, B15, B16, B35, B42, B53).Conclusions: Genetic factors do have a role in the development and expression of Systemic lupus erythematosus . human leukocyte antigen -A28 , A36, B12 and B21 had an association with Systemic lupus erythematosus Iraqi patients.Key words: Human Leukocyte Antigens, Systemic Lupus Erythematosus , Tissue typing


Article
Frequency of Antineutrophil Cytoplasmic Antibodies (ANCA) in Some Autoimmune Diseases

Authors: Husam M. Abbas --- Falah S. Manhal
Journal: Iraqi Journal of Pharmaceutical Sciences المجلة العراقية للعلوم الصيدلانية ISSN: 16833597 Year: 2009 Volume: 18 Issue: 2 Pages: 55-60
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Anti-Neutrophil Cytoplasmic Antibodies (ANCA) are a heterogeneous group of autoantibodies with a broad spectrum of clinically associated diseases. The diagnostic value is established for Proteinase 3 (PR3)-ANCA as well as Myeloperoxidase (MPO)-ANCA. To estimate the frequency of anti-neutrophile cytoplasmic antibodies (ANCA) in sera from a group of Iraqi patients with some autoimmune diseases compared with a healthy control group. Serum samples were collected from one hundred patient, 47 males and 53 females; with age range of 16-70 years; 20 specimens from patients with systemic lupus erythematosus (SLE), 30 from patients with ulcerative colitis (UC), and 50 from patients with rheumatoid arthritis (RA). A group of 40 apparently healthy blood donors was included as controls. ANCA were checked using enzyme-linked immunosorbent assay (ELISA). Positive ANCA was detected in sera of 18 (18%) patients with autoimmune disorders. Anti-PR3 was detected in 6 (12%) patients with RA, and in 4(13.4%) patients with UC. Anti-MPO was detected in 3(6%) patients with RA and in 5(16.6%) patients with UC. All serum samples of patients with SLE showed negative ANCA. There were no ANCAs detected in sera from healthy individuals. Mean of serum anti-PR3 (U/ml) among the studied groups was 2.057 in RA, 2.209 in SLE, and 2.283 in UC, and 1.739 in control group. Statistical analysis revealed that differences in the anti-PR3 between RA, UC and controls were highly significant (P > 0.01), whereas just significant with SLE (P> 0.05). Mean of serum of anti-MPO (U/ml) among the studied groups was 0.711 in RA, 0.695 in SLE, and 1.170 in UC, and 0.652 in control group. Statistical analysis revealed that the differences in the anti-MPO between RA and SLE, controls were non significant (P < 0.05), whereas highly significance with UC (P> 0.01).It was concluded that ANCA markers might play a role in the inflammatory process and they are important factors for the clinical course, and prognosis in the patients with autoimmunity. However, ANCA in autoimmune disorders must be interpreted cautiously with particular attention paid to laboratory technique, the size, age and genetic background of the populations studied.

الأجسام السايتوبلازمية المضادة للخلايا المتعادلة هي مجموعة مختلفة من الاجسام الذاتية ذات طيف واسع من الامراض المرتبطة سريريا .تم اجراء هذه الدراسة للفترة من تشرين الثاني 2006 لغاية شباط 2007 لغرض تقدير نسبة تكرار الاجسام السايتوبلازمية المضادة للخلايا المتعادلة (ANCA) في أمصال مجموعة من المرضى العراقيين المصابين ببعض الأمراض ذاتية المناعة مقارنة بالمجموعة الضابطة للأصحاء . تم جمع 100 عينة مصل من المرضى (47 ذكور و 53 أناث بمعدل عمري 16-70 سنة) ، 20 عينة من المصابين بداء الذئاب الحماموي المجموعي ، و30 من المصابين بالتهاب القولون التقرحي ، و50 عينة من المصابين بالتهاب المفاصل الرثوي . جمعت 40 عينة مصل من بعض المتبرعين الأصحاء في مصرف الدم كمجموعة ضابطة . تم التحري عن وجودANCA باستخدام تقنية المقايسة المناعية الإنزيمية (ELISA) . تم تشخيص هذه الاجسام المضادة في 18 (18%) من كل المرضى . ظهر anti-PR3 في 6 (12%) من المصابين بالتهاب المفاصل الرثوي وفي 4(13.4%) في مرضى التهاب القولون . ظهر anti-MPO في 3 (6%) من مرضى التهاب المفاصل الرثوي ، و (16.6%)5 من مرضى التها ب القولون. كانت النتائج سالبة في داء الذئاب الحماموي المجموعي. لم تظهر هذه الاجسام في المجموعة الضابطة . ظهر من خلال هذه الدراسة ان متوسط anti-PR3 (وحدة / سم 3) بين المجاميع التي درست كان 2.057 في التهاب المفاصلالرثوي ، 2.209 في داء الذئاب الحماموي المجموعي ، و 2.283 في التهاب القولون التقرحي ، و1.739 في المجموعة الضابطة . أظهر التحليل الإحصائي بان الاختلاف في anti-PR3 بين التهاب المفاصل والتهاب القولون التقرحي مقارنة بالمجموعة الضابطة كان معنويا بشكل عال P) < 0.01 ) ، في حين كان الاختلاف معنويا فقط في داء الذئاب P) < 0.05 ) . ظهر كذلك ان متوسط anti-MPO (وحدة / سم 3) كان 0.711 في التهاب المفاصل ، و 0.695 في داءالذئاب الحماموي ، و 1.170 في التهاب القولون التقرحي ، و 0.652 في المجموعة الضابطة . ظهر كذلك ان الاختلاف في النتائج بين التهاب المفاصل وداء الذئاب الحماموي ومجموعة السيطرة كان غير معنوي P) > 0.05 ) في حين كان الاختلاف معنويا بشكل عال مع التهاب القولون التقرحي P) < 0.01 ) . يستنتج من هذه الدراسة بان الأجسام السايتوبلازمية المضادة للخلايا المتعادلة ((ANCA قد تلعب دورا في العملية الالتهابية وتحديد المسار السريري ومصير المرضى المصابين بامراض المناعة الذاتية . ولكن وجود هذه الاجسام المضادة يجب ان يشخص بحذر في امراض المناعة الذاتية مع تركيز الانتباه على تقنية الفحص و عدد واعمار المرضى وخلفيتهم الوراثية.


Article
Prevalence of Abnormal Ankle –Brachial Index in Iraqi Patients with Systemic Lupus Erythematosus

Author: Ziad S. Al-Rawi
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2012 Volume: 11 Issue: 2 Pages: 187-192
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

ABSTRACT:BACKGROUND:Accelerated atherosclerosis is a well-recognized complication of systemic lupus erythematosus (SLE). Its etiology is a multifactorial and several methods may be used to detect the presence and severity of peripheral arterial disease (PAD).OBJECTIVE:To assess ankle brachial index (ABI) in Iraqi patients with SLE, and to evaluate predictors of this relationship.PATIENTS AND METHODS:Forty three Iraqi SLE patients and 50 healthy controls were included in this study. Full history was taken and complete clinical examination was done for all individuals in both groups. Disease characteristics [age, sex, body mass index (BMI), duration of disease, SLE disease activity index (SLEDAI), smoking history, family history, hypertension, hyperlipidemia, thrombosis, Raynaud’s phenomenon and drugs used] were also documented. Laboratory analysis included complete blood count, general urine examination, serum lipid profile, fasting blood sugar, thyroid function tests, anti-double stranded deoxyribonucleic acid (anti-ds-DNA), complements components and anti-phospholipid anti-bodies. Individuals in both groups were assessed using the ABI. The ABI was measured using a contour wrapped 12cm cuff attached to a mercury sphygmomanometer and 5-10 MHz Doppler in the arms and legs; a ratio of ≤0.9 was considered abnormal. Abnormal ABI was categorized as mild, moderate and severe.RESULTS:Seven (16%) Iraqi SLE patients have abnormal ABI compared with 0% of controls (P=0.010). All patients were of mild abnormal ABI(P=0.003).There was significant association between abnormal ABI and: sex, smoking history, and cyclophosphamide therapy (P=0.000, P=0.001, P= 0.020 respectively) but there was no significant association between abnormal ABI; and other patients’ characteristics[ age, BMI, duration of disease, SLEDAI, family history, hypertension, thrombosis, Raynaud’s phenomenon, or drugs used (steroid, mycophenolate mofetil, hydroxychloquin, non-steriodal anti-inflammatory drugs and statins)] (P=0.579, P=0.754, P=0.823, p=0.148, P=0.655, P=0.233, P=0.655, P=0.241, P=0.512, P=0.335, P=0.315, P=0.655 , P=0.185) respectively.CONCLUSION:Mild abnormal ABI occurs with high frequency (16%) in Iraqi SLE patients. Males, smoking history, and cyclophosphamide therapy are significant predictors


Article
Hormonal and Immunological Disturbances in Patients with Rheumatoid Arthritis and Systemic Lupus Erythematosus

Author: Numman Hamed. Salih
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2008 Volume: 7 Issue: 1 Pages: 65-70
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

ABSTRACT:BACKGROUND:Rheumatoid arthritis and systemic lupus erythematosus are multifactorial autoimmune diseases.Some recent reports indicated a hormonal disturbances affected the balance between Th1 and Th2lymphocyte response.OBJECTIVES:To investigate the immunological and hormonal disturbance in patient with rheumatoid arthritis(RA) and systemic lupus erythematosus (SLE).METHODS:Serum samples, were collected from patients with RA, SLE and control, then the tests forantinuclear antibodies, anti double strand DNA, anticardiolipin antibodies are done by usingEnzyme linked immuno assay (ELISA) method. Also, hormonal studies including estrogen,progesterone and prolactin level are done by using the Radio immunoassay technique (RIA).RESULTS:The results indicated the increasing of ANA, anti ds-DNA, and anticardiolipin antibodies. Also,elevation in the levels of estrogen, progesterone and prolactin in patients with RA and SLEcomparing with control.CONCLUSION:Immunological and hormonal disturbances in patients with RA and SLE were documented throughthrough the increasing of ANA, anti dsDNA anticardiolipin antibodies and elevation of the level ofestrogen, progesterone, and prolactin.


Article
Possible Role of Anti-Cyclic Citrullinated Peptide Antibody (Anti-CCP Ab) in Rheumatic Diseases
الدور المحتمل للاجسام المضادة لبيبتيدات ال Cyclic Citrullinated(اضداد ال CCP) في الامراض الروماتيزمية

Authors: Eman Sh. Al-Obeidy ايمان العبيدي --- Nahida R. Abbas نادية عباس --- Karim S. Ali Al-Ajeeli كريم سعدون العجيلي
Journal: Diyala Journal of Medicine مجلة ديالى الطبية ISSN: 97642219 Year: 2012 Volume: 3 Issue: 1 Pages: 82-89
Publisher: Diyala University جامعة ديالى

Loading...
Loading...
Abstract

Background: Anti-cyclic citrullinated peptide (anti-CCP) antibodies are highly specific for RA, but are not detectable in all RA patients, in addition their usefulness to identify rheumatic arthritis (RA) from other rheumatic diseases presenting with joint pain is not well studied.Objective: To establish whether the clinical phenotypes of anti-CCP positive and negative disease are distinct at the earliest clinically apparent phase of disease and to assess the diagnostic accuracy of the anti-CCP antibodies assay to separate RA patients from a group of patients with (SLE).Patients and Methods: One hindered ten blood samples were collected from patients, 75 with RA (58 seropositive and 17 seronegative) and 35 patients with SLE attending the Rheumatology Clinic of the Al-Yarmook Teaching Hospital for period between March 2009 and November of 2010 were included in this study. Then sera were stored at -20° and tested for anti-CCP antibodies by a commercially available enzyme-linked immunosorbent assay (ELISA) kit (Euroimmun, while CRP and Rheumatoid factor was test by latex agglutination (LA). Results: Forty five of 58 seropositive RA patients (77.6%) were positive for anti-CCP, while 13 patients tested negative for anti-CCP antibodies. Among the seronegative group, antibodies to anti-CCP could be demonstrated in 22.4% of patients. Anti-CCP positive patients were rheumatoid factor positive (77.6% vs. 22.4%, p < 0.005). There was no significant difference in the pattern of joint involvement. In the SLE group, anti-CCP antibody was positive in only 8 of 35 (22.8 %) patients. Conclusions: Patients with and without anti-CCP antibodies present in a similar way, and anti-CCP antibody have high sensitivity for diagnosis of RA.Keywords: Anti-CCP antibodies, C-reactive protein, rheumatoid arthritis, rheumatoid factor, systemic lupus erythematosus.

الخلفية: ان الاضداد المضادة للبيبتيد الحلقي cyclic citrullinated peptide هي عالية التخصص كأجسام مضادة لالتهاب المفاصل الروماتويدي، ولكن لا يمكن كشفها في كل مرضى التهاب المفاصل الروماتويدي، بالإضافة الى ذلك فان فائدتها لتحديد التهاب المفاصل الروماتيزمية (RA) من الأمراض الروماتيزمية الأخرى المصحوبة بآلام في المفاصل لم تدرس جيدا.الاهداف: لتحديد ما إذا كانت الظواهر السريرية للمرض الموجب او السالب لمضادات ال CCP هي مميزة في المرحلة السريرية المبكرة للمرض وتقييم الدقة التشخيصية لفحص الأجسام المضادة المقاومة لل CCPلفصل مرضى التهاب المفاصل الروماتويدي عن مجموعة من المرضى الذين يعانون من (SLE)النتائج: اظهرت النتائج ان خمسة وأربعين من 58 مريضا من المرضى الموجبين مصليا لمرضى التهاب المفاصل الروماتويدي (77.6٪) موجبين ايضا لاضداد الCCP ، في حين أن 13 مريضا ظهروا سالبين لاضداد ال CCP.اما المرضى السالبين مصليا لمرض التهاب المفاصل فقد تبين ان 22,4% منهم هو موجب لاضداد ال CCP. وظهر ايضا ان المرضى الموجبين لاضداد ال CCP هم ايضا موجبين ل rheumatoid factor (0,005>p , 22,4% .vs77,6%)لم تظهر اية فروق معنوية في نمط شمول المفاصل.وظهر في مجموعة ال SLE ان 8 مرضى من 35 مريضا (22,8% ) هم موجبين لاضداد ال CCP.الاستنتاجات: المرضى مع وبدون اضداد ال CCP ظهروا بشكل متشابه وان اضداد ال تمتلك حساسة عالية لتشخيص الامراض الروماتيزمية.

Listing 1 - 10 of 10
Sort by
Narrow your search

Resource type

article (10)


Language

English (9)

Arabic and English (1)


Year
From To Submit

2012 (5)

2010 (1)

2009 (2)

2008 (1)

2006 (1)