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Article
Effect of Serum Zinc Concentration Amongst Pregnant Women in Mosul
تأثير تركيز الخارصين على نساء الموصل الحوامل

Authors: Wael Abd-Alkader وائل عبد القادر --- Luma M. Tohala لمى معتصم توحلة --- Bassam E. Hanna بسام ادور حنا
Journal: Rafidain journal of science مجلة علوم الرافدين ISSN: 16089391 Year: 2011 Volume: 22 Issue: 4E Pages: 51-61
Publisher: Mosul University جامعة الموصل

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Abstract

The study was conducted in Mosul during the period from february to april 2009 including non-married and pregnant group composed of 35 and 105 apparently healthy women respectively, pregnant group were subdivided equally according to their trimester into three subgroups, women in second and third trimester are having ferrous sulphate in their ingestion. Serum zinc measurement were done for these groups of women. The results showed that serum zinc concentration start to reduce significantly during second trimester continue to decline in third trimester in comparison with non-married group. Therefore, it is recommended to measure serum zinc during pregnancy with use of optimal dose of zinc supplemental therapy.

أجريتْ الدراسة في مدينةِ الموصل خلال الفترةِ مِنْ فبراير/شباطِ إلى أبريل/نيسانِ 2009 متضمنة مجموعه من النساء غير المتزوجات والحبالى متكونة من 35 و 105 امرأة على التوالي. مجموعة الحبالى قُسّمتْ بالتساوي طبقاً لثُلثِ الحملِ إلى ثلاث مجاميع فرعيةِ, وان النِساء في الثلثين الثاني والثالث من الحمل كُنَ يتناولن كبريتات الحديدوز وتم قياسُ تركيزِ الخارصينِ لمصل الدم لهذه المجاميع من النساء. دلت النتائج على أن تركيز الخارصينِ لمصلِ الدم بدا بالانخفاض المعنوي أثناء الثُلثِ الثانيِ من الحمل وواصلُ الهُبُوط في الثُلثِ الثالثِ بالمقارنة مع مجموعة غير المتزوجات. لذا يُوصي البحث بقياس الخارصينِ لمصلِ الدم أثناء الحمل و استعمال علاجِ الخارصينِ الداعم بجرعٍ مثاليةِ

Keywords

Zinc --- Pregnancy --- Trimester


Article
Serum Magnesium and Copper Levels Amongst Pregnant Women in Mosul City
مستويات المغنيسيوم والنحاس في مصل النساء الحوامل في مدينة الموصل

Author: Luma M. Tohala لمى معتصم توحلة
Journal: Rafidain journal of science مجلة علوم الرافدين ISSN: 16089391 Year: 2012 Volume: 23 Issue: 1E Pages: 68-78
Publisher: Mosul University جامعة الموصل

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Abstract

The study was conducted in Mosul during the period from September 2010 to March 2011 including two groups: the first non-pregnant women and the second pregnant women composed of 40 and 120 apparently healthy women respectively. Pregnant group was subdivided equally according to their trimester into three subgroups, women in second and third trimester having ferrous sulphate supplement. Serum magnesium and copper measurements were done for these groups of women.The results showed that serum magnesium concentration start to reduce significantly during first trimester continue to decline in second and third trimesters in comparison with non-pregnant group. Serum copper concentration start to increase significantly during first trimester continue to increase in second and third trimesters in comparison with non-pregnant group.

أجريتْ الدراسة في مدينةِ الموصل خلال المدة مِنْ أيلول 2010 إلى آذار 2011 متضمنة مجموعتين: الأولى نساء غير حوامل، والثانية نساء حوامل متكونة من 40 و 120 إمرأة على التوالي, مجموعة النساء الحوامل قُسّمتْ بالتساوي اعتمادا على فترة الحمل إلى ثلاث مجاميع فرعية, النساء في الثلثين الثاني والثالث من الحمل يتناولن كبريتات الحديد. وتم قياس تركيز المغنيسيوم والنحاس في مصل الدم لكل مجموعة من هذه المجاميع. دلت النتائج على أن تركيز المغنيسيوم بدأ بالانخفاض المعنوي أثناء الثُلث الأول من الحمل وواصل الهُبُوط في الثُلث الثاني الثالث بالمقارنة مع مجموعة النساء غير الحوامل. أما تركيز النحاس فبدأ بالارتفاع المعنوي أثناء الثلث الأول وواصل الارتفاع في الثلث الثاني والثالث

Keywords

Magnesium --- Copper --- Pregnancy --- Trimester


Article
Evaluation of serum leptin in normal pregnant and non-pregnant women
تقييم مصل لبتين لدى النساء الحوامل وغير الحوامل

Authors: Sardar Nouri Ahmed --- Feedan Tahseen --- Fargeen Ezzaddin
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2018 Volume: 22 Issue: 3 Pages: 315-322
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objectives: Leptin influences satiety, adiposity, and mechanism is with mechanisms regulating puberty onset, fertility, and pregnancy in various species. This study aimed is to evaluate the serum leptin levels indifferent trimesters of pregnancy and compare with healthy non-pregnant women.Methods: The study was carried out in Erbil city from January to July 2016. Blood specimens were collected in different medical health centers in Erbil city. The sample consisted of two groups; group one consisted of 60 pregnant healthy female individuals. The pregnant group consisted of three subgroups according to the first, second and third trimesters. Group two (control) consisted of 28 healthy non-pregnant female individuals.Results: There were statistically significant (P <0.003) elevation in serum leptin in pregnant compared with the non-pregnant group, and among trimesters. Serum leptin in the second trimester was significantly (P <0.001) higher than that of the first and the third trimesters.Conclusion: Our finding showed that increased serum leptin concentration especially in the second trimester for development of placenta and fetus as a function of leptin.


Article
Use of single serum progesterone level measurement as a predictor of the fetal viability during the first trimester
استخدام قياس مستوى هرمون البروجسترون في الدم كمؤشر على سلامة الجنين خلال الأشهر الثلاثة الأولى

Author: Trifa Yousif Muttalib
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2018 Volume: 22 Issue: 2 Pages: 180-185
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objective: Approximately one in third of pregnant women experience discomfort, pain and or vaginal bleeding during the first trimester of pregnancy. Ultrasound is known to be a useful tool in detecting and diagnosing the viability of the fetus but it is sometimes inconclusive. In cases in which pregnant women experience symptoms of discomfort, serum progesterone may be admitted to the patient for counseling and prediction of the continuity of pregnancy. This study aimed to estimate the relation between single serum progesterone level and the viability of the fetus during the first trimester.Method: A prospective study was carried out in Maternity teaching hospital-Erbil city to estimate the accuracy of single serum progesterone measurement for the prediction of fetal viability at the end of the first trimester. All the cases have been detected by ultrasound device that has been for women who attended the hospital and reported the feeling of discomfort, pain and bleeding early in the first trimester of pregnancy, serum progesterone level of the patients were compared between viable and nonviable fetuses.Results: A total of 97 participants were involved in this study; 57 participants had a viable pregnancy at the end of the first trimester, and 40 participants had un-viable pregnancy that has been terminated either by spontaneous abortion or termination performed for missed abortion. The mean of serum progesterone level in viable pregnancies was (19.358 ngml) when compared with the non-viable pregnancies which were (11.082 ngml). The differences were statistically significant (P <0.001). The cut-off value (13.68ngml) provides the highest sensitivity and specificity.Conclusion: A single serum progesterone measurement was regarded as a reliable test for the prediction of viable and non-viable pregnancy in women who reported to be experiencing pain and bleeding in the early trimester of pregnancy with or with inconclusive ultrasound.


Article
Misoprostol for termination of first trimester missed abortion

Author: Maha Assim AL- Azzawy مها عاصم العزاوي
Journal: Al-Qadisiyah Medical Journal مجلة القادسية الطبية ISSN: 18170153 Year: 2009 Volume: 5 Issue: 7 Pages: 121-141
Publisher: Al-Qadisiyah University جامعة القادسية

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Abstract

Background: misoprostol is prostaglandin E1 analogue that can be given by oral, sublingual, vaginal or rectal route. It is cheap and can be stored at room temperature and because of its utero-tonic action, it become an important drug in obstetric and gynecological practice.Objectives: to evaluate the effectiveness of intravaginal followed by oral misoprostol tablets for medical termination of missed abortion between 8 – 13 weeks.Methods : a prospective study of (60) women with diagnosed missed abortion admitted to AL- Zahraa General hospital – Wassit Governorate Iraq from July 2006 through July 2007 . 800 micrograms (4 tablets) of misoprostol inserted in the posterior fornix of the vagina after moisture with normal saline followed by oral 400 micrograms (2 tablets) 6 hours later. Another 400 micrograms were given orally 6 hours from the last dose for those patients whodid not respond to the previous two doses.Results: (48) patients (80%) had complete expulsion . (21) Patients (35%) after the vaginal dose. (15) Patients (25%) respond after the first oral dose and (12) patients (20%) after the second oral dose. (6) Patients (10%) had incomplete abortion; the remainder (6) patients (10%) failed to respond within 24 hours of starting treatment and require surgical evacuation. The mean time for expulsion was 10 hours. Conclusion: first trimester missed abortion medical termination by misoprostol is effective, save and a practical Methods .

الميزوبرستول هو مثيل البروستوكلاندين- اي 1 ويمكن ان يعطى عن طريق الفم وتحت اللسان و عن طريق المهبل وعن طريق الشرج. يعتبر هذا العقار رخيصا و ممكن خزنه في درجة حرارة الغرفه و بسبب فعاليته في احداث تقلصات رحميه اصبح عقارا مهما في مجال النسائيه و التوليد.الهدف من الدراسة هو لتقييم فعالية الميزوبرستول وذلك بأعطائه عن طريق المهبل يليه اعطائه عن طريق الفم لانهاء الاسقاط المنسي طبيا بين 8 – 13 اسبوع. هذهِ دراسه مستقبليه تضمنت ستون امرأه مشخصه بحالة اسقاط منسي ادخلوا مستشفى الزهراء العام في محافظة واسط / العراق للفتره بين تموز 2006 و تموز 2007 . 800 مايكروكرام ( اربع حبوب) من الميزوبرستول توضع في الجزء الخلفي من المهبل بعد ترطيبها بالنورمال سلاين تليها جرعه عن طريق الفم (400 مايكروكرام) بعد ستة ساعات . وجرعه فمويه اخرى بعد ستة ساعات من الجرعه الاخيره للمرضى الذين لم يستجيبوا للجرعتين الاوليتين.النتائج 48 مريضه (80%) حصل اسقاط كامل. 21 منهن(35%) بعد الجرعه الاولى. 15مريضه (25% ) بعد الجرعه الفمويه الاولى و 12 مريضه (20%) بعد الجرعه الفمويه الثانيه .6مريضات (10%) انتهوا بأسقاط ناقص و 6 مريضات (10%) لم يستجيبوا للعلاج بعد مرور 24 ساعه على بدأ العلاج واحتاجوا الى تداخل جراحي لانهاء الحمل. كان معدل وقت انهاء الاسقاط المنسي هو عشرة ساعات .يستنتج من الدراسة انهاء الحمل الطبي في حالات الاسقاط المنسي في الجزء الاول من الحمل بواسطة الميزوبرستول هي طريقه فعاله و امينه وعمليه.


Article
The association of anticardiolipin antibody IgM with first trimester recurrent abortions
العلاقة بين الجسم المضاد للدهون من نوع آي جي آم والإسقاطات المتكررة خلال أول ثلاثة اشهر من الحمل

Author: Dr. Mohammad Shnain Ali
Journal: KUFA MEDICAL JOURNAL مجلة الكوفة الطبية ISSN: 1993517X Year: 2010 Volume: 13 Issue: 2 Pages: 157-161
Publisher: University of Kufa جامعة الكوفة

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Abstract

AbstractBackground: Anticardiolipin antibody has a clearly documented association with recurrent abortions in patients with autoimmune diseases; however, the association of Anticardiolipin antibody with first trimester abortions is not clearly documented in patients with no evident autoimmune diseases.Aim: To estimate the prevalence of Anticardiolipin antibody IgM in patients with first trimester recurrent abortions and to find if there is any association between them.Materials and methods: A total number of 90 women were included, 45 had history of recurrent abortions(more than 2 abortions) and 45 were healthy control women with one or more than one delivery and no history of abortions. Blood samples from the 90 women were taken for investigations including blood group, blood sugar, blood urea, complete blood picture, ESR, general urine examination, TORCH test, VDRL test and Anticardiolipin antibody IgM by ELISA technique in which levels higher than 15 MCL unit are considered to be positive, while levels below 15 MCL unit are considered to be negative.Results: Out of 45 patients, 24.4%(n=11) had history of explained recurrent abortions, 9 of them due to toxoplasmosis and 2 of them were due to cytomegaloviral infection. while 75.6%(n=34) had no explained causes. Significantly raised levels of anticardiolipin antibody IgM was present in 11 out of 45 patients i.e 24.4% of patients while IgM levels were normal in 34 out of 45 patients i.e 75.6%. The total number of explained recurrent abortions was 11 (8 out of 11 had significantly high IgM antibody i.e 72.7% while 3 out of 11 had normal IgM levels i.e 27.3%). The total number of unexplained recurrent abortions was 34 ( 3 out of 34 had significantly high anticardiolipin antibody IgM i.e 8.8% while 31 out of 34 patients had normal levels i.e 91.2%) while the antibody was negative (normal) in the control group. Patients with significantly high levels of anticardiolipin antibody who had history of explained recurrent abortions are eight. Seven of them i.e 87.5% had positive antitoxoplasma antibody IgM and one of them i.e 12.5% had positive anticytomegalovirus antibody IgM. Conclusion: Anticardiolipin antibody IgM is not associated with first trimester recurrent abortions.

الخلاصةالخلفية: للجسم المضاد للدهون علاقة مثبتة مع الاسقاطات المتكررة في حالة وجود الامراض المناعية المكتسبة مع ذلك فان العلاقة غير مثبتة في حالة عدم وجود الامراض المناعية المكتسبة. الغرض: معرفة وجود او عدم وجود علاقة بين الجسم المضاد للدهون من نوع آي جي ام والاسقاطات المتكررة خلال اول ثلاثة اشهر من الحمل.المواد والطرق: تمت دراسة 90 حالة(45 من النساء الحوامل ممن لهم اكثر من حالتين من الاسقاطات اول ثلاثة اشهر من الحمل و 45 من النساء ممن لهم اكثر من ولادة طبيعية وليس لديهم أي حالة اسقاط كمجموعة تتمتع بالصحة). تم جمع عينات الدم والادرار لاجراء التحليلات المرضية التالية: فصيلة الدم,نسبة السكر في الدم, يوريا الدم,صورة الدم الكاملة,نسبة ترسيب الكريات الحمراء,تحليل الادرار العام, اختبار تورج, اختبار السفلس, والجسم المضاد للدهون من نوع آي جي ام بطريقة اليزة وتم اعتبار المستوى الاعلى من 15 وحدة ايجابيا والمستوى الاقل او يساوي 15 سلبيا. النتائج: وجدت نسبة 24.4%(عدد 11) ممن لديهم اسقاطات متكررة مفسرة(9 منهم بسبب داء القطط و 2 منهم بسبب السايتوميجالوفايروس)بينما نسبة 75,6%(عدد 34) ممن ليس لديهم اسباب لتفسير الاسقاطات المتكررة. وجد ان مستويات الجسم المضاد للدهون من نوع آي جي ام بطريقة اليزة عالية احصائيا لدى 11 من مجموع 45 مريضة أي 24.4%(8 مرضى ممن لديهم اسقاطات متكررة أي 72.8% و 3 مرضى فقط ممن لديهم اسقاطات غير مفسرة الاسباب أي 8.8%)الاستنتاج: لا توجد علاقة بين الجسم المضاد للدهون من نوع آي جي ام والاسقاطات المتكررة خلال اول ثلاثة اشهر من الحمل في حالة عدم الاصابة بالامراض المناعية.


Article
BODY MASS INDEX AND TOTAL SERUM LEPTIN LEVEL IN ABORTION

Authors: Nesreen A. Nasser نسرين احمد ناصر --- May F. Al-Habib مي فاضل ماجد الحبيب --- Rayah S. Baban ريا سليمان بابان
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2013 Volume: 11 Issue: 4 Pages: 361-367
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Background:Adipose tissue secretes variety of adipokines, including leptin, which is involved in endocrine processes regulating reproduction and plays an important role in energy metabolism and fetal development during pregnancy.Objectives:To investigate the relationship between total serum leptin concentrations and anthropometric parameters including body mass index (BMI) in aborted women at the second trimester.Methods:A case control study was carried out from November 2011 to April 2012. The patients' group includes 30 aborted women at the second trimester. They were collected from Al-Elweyia, Al-Hakeem and Al-Khadhemiyia Teaching Hospital in Baghdad. Thirty healthy pregnant women (at their second trimester of gestation) were used as control. Patients and control were comparable in age. Blood HbA1c and serum concentrations of total leptin, lipid profile, and glucose were measured in both groups.Results:Total serum leptin concentration were significantly lower in those with abortion at the second trimester compared with healthy pregnant control (3.5±0.8 pg/ml vs. 24.4±0.7 pg/ml, P = 0.0001) and leptin/BMI ratio vs. control (0.1±0.02 vs. 0.9±0.01 ml, P=0.0001). No correlation was found between leptin level and patient’s age or gestational age in the case group. Highly significant correlation was found between patient’s total serum leptin and their body mass index, HDL-C, total cholesterol/HDL-C ratio and atherogenic index (P < 0.0001).Conclusion:The significant correlation between patient’s leptin and their BMI in addition to Leptin/BMI ratio even in non obese patient supports our objective that the unexplained abortion at second trimester is due to abnormality in their metabolic hormone action and reflect leptin resistance condition.Keywords:Second trimester abortion, Leptin, BMI, Gestational age.


Article
VAGINAL MISOPROSTOL FOR SECOND TRIMESTER PREGNANCY TERMINATION IN WOMEN WITH PRIOR ONE CAESAREAN DELIVERY

Author: Enas A.A. Al-Kazaaly ايناس عدنان عبد الرسول
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2014 Volume: 12 Issue: 3 Pages: 238-244
Publisher: Al-Nahrain University جامعة النهرين

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Background:Misoprostol, a synthetic prostaglandin analogue, has become the leading mean for terminating the pregnancy. It is not clear, however, whether misoprostol is a safe abortifacient after thirteen weeks gestation in women who have a uterine scar from a previous lower segment caesarean delivery.Objective:To evaluate the efficacy and maternal side effects of misoprostol used vaginally for second trimester termination in women with a single previous lower segment caesarean delivery.Method:Sixty participants with a history of previous one lower segment caesarean delivery underwent pregnancy termination for missed abortion or lethal fetal anomaly between 14-28 weeks gestation using intra vaginal misoprostol. The dose of which was 400 microgram up to 20 weeks gestation and 200 microgram thereafter, repeated every 4 hours with a 12 hours nightly rest from misoprostol application up to a maximum of 72 hours. Women having termination for similar reasons but lacking a history of cesarean section served as a control group.Results:Abortion rate was 96.66% in the study group and 95% in the control group. The mean induction to abortion interval was 21.81±9.51 for the study group and 22.21±8.52 for the control group with no significant difference between the two groups. No cases of uterine rupture occurred in either groups.Conclusion:Inducing abortion with lower misoprostol doses appear to be safe and effective throughout the second trimester in women with a single previous lower segment cesarean delivery.Keywords:Second trimester, Misoprostol, Termination of pregnancy


Article
Oral Misoprostol Versus Vaginal Surgical Evacuation of First Trimester Incomplete Abortion; A comparative Study

Authors: Falah Abdul Hade Muhi1 --- Haitham F. Hamzha
Journal: Karbala Journal of Medicine مجلة كربلاء الطبية ISSN: 19905483 Year: 2015 Volume: 8 Issue: 1 Pages: 2167-2171
Publisher: Kerbala University جامعة كربلاء

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Abstract

background: Vaginal surgical evacuation of retained products of conception was the main stay of treatment for a long time for patients with first trimester incomplete abortion. Misoprostol as a thermo stable prostaglandin E1 analogue has been previously tested in the management of incomplete miscarriage in different regimens and setting. Overall results indicate efficacy, effectiveness and acceptability in most of these studies.Objectives: To assess the effectiveness and acceptability of using oral misoprostol for management of first trimester spontaneous incomplete abortion as an alternative to direct vaginal surgical evacuation.Methods: This is a comparative study performed on 84 patients with first trimester incomplete abortion between 6 -12 weeks of gestation requesting medical management .They were divided into two groups; group (1) received misoprostol tablet 200 μg [misotac ,SIGMA] two tablets every 4 h for a maximum of four doses while group (2) underwent surgical vaginal evacuation directly under general anesthesia.Results: In 100% of cases , misoprostol was successful in 79% (p= 0.0006). The overall satisfaction was slightly higher in the surgical group but almost equal percentage of both groups mentioned that they will recommend the method to a friend. No serious side effects or complications were reported in misoprostol group. The incidence of excessive post-abortive bleeding was more in the misoprostol group than the surgical evacuation group (p=0.336). Also endometrial thickness using ultrasonography was significantly thicker in the misoprostol group than group (2) [p=0.0071].Conclusion: Although vaginal surgical evacuation is more effective than misoprostol in solving the problem still medical treatment is effective and acceptable especially when surgical management is not available or risky or patients refuse to do surgical management.


Article
Quantitative study of some trace elements and blood parameters in the third trimester of Iraqi pregnant women with Pre-eclampsia
دراسة كمية لبعض العناصر الثقيله ومعايير الدم في الربع الثالث من الحمل في النساء الحوامل العراقيات المصابات بتسمم الحمل.

Authors: Lina A. Salih لينا عبد المطلب صالح --- Mahmood B. Mahmood محمود باسل محمود
Journal: Iraqi Journal of Science المجلة العراقية للعلوم ISSN: 00672904/23121637 Year: 2016 Volume: 57 Issue: 3C Pages: 2197-2202
Publisher: Baghdad University جامعة بغداد

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Abstract

Pre-eclampsia complicates 2-8% of all pregnancies and it is one of the leading causes of maternal mortality and pre-term delivery in the world. Unfortunately, there is scarcity of documents discussing the circulating level of several essential trace elements in Pre-eclampsia patients in Baghdad especially in the last trimester of the pregnancy. The present study was designed to quantitative evaluation the whole blood concentration of two trace elements, copper (Cu), and iron(Fe), in pre-eclamptic women in the third trimester of pregnancy. The study was conducted on 18 Pre-eclamptic pregnant women as patients group with clinical detected high blood pressure ≥140/90 mmHg and 13 normotensive pregnant women as control group from Al-Alwiya for obstetric and gynecological hospital, clinical data were collected at routine obstetric visits. Hemoglobin (Hb) ,Packed cell volume (pcv) and measurements of 2 trace elements concentrations were measured in the whole blood of both patients and control group. Hematological parameters measurements explored non-significant differences was found in Hb value and pcv between the patients and the control group, although their mean levels were increased in the patients compared to the control group. According to the statistical analysis it was noticed there was non-significant differences (P>0.05) was found in the concentration of the copper between patients and control group. But significant (P<0.05) elevated concentration of Fe was conducted in the pre-eclamptic patients compared to the control. In conclusion, our study suggest that pre-eclampsia in the third trimester is associated with significant increase of maternal blood iron and these increasing levels may be lead to increase the risk of pre-eclampsia in pregnant women.

يشكل تسمم الدم الحملي نسبة 2-8% من مجموع حالات الحمل وهو احد الاسباب المؤدية لموت الام والولادة المبكرة في العالم. ولان المصادر التي تناولت مستويات العناصر النادرة في دم الحوامل المصابات بتسمم الدم الحملي في مدينة بغداد مازالت شحيحة خصوصا خلال الربع الاخير من الحمل. وضعت هذه الدراسة للتقييم الكمي لتركيز عنصرين من المعادن الثقيلة, النحاس والحديد في دم النساء الحوامل المصابات بتسمم الحمل في الاشهر الثلاث الاخيره من الحمل. اجريت الدراسة على 18 حامل مصابه بتسمم الحمل اعتبرت مجموعه المرضى مع التشخيص السريري لارتفاع ضغط الدم اكثر من 140/90 ملم زئبق و 13 امرأة حامل سليمة كمجموعه سيطرة من مستشفى العلوية للولادة, تم جمع المعلومات السريرية من خلال الزيارات الروتينية للعيادة النسائية في المستشفى. تم قياس تراكيز الهيموغلوبين وحجم الخلايا المضغوط وعنصرين من العناصر الثقيلة في الدم الكلي لمجموعتي المرضى والسيطرة.وجد عدم ظهور فروق معنويةفي معاييرالدم(الهيموغلوبين وحجم الخلاياالمضغوط) بين مجموعه المرضى ومجموعه السيطرة بالرغم من ان معدلاتها كانت مرتفعه في مجموعه المرضى مقارنه مع مجموعه السيطرة, اعتمادا على التحليل الاحصائي فقد وجد عدم وجود فرق معنوي(P<0.05) في تركيز النحاس بين مجموعه المرضى ومجموعه السيطرة لكن وجد ارتفاع معنوي(P>0.05) في تركيز الحديد في دم الحوامل المصابات بتسمم الحمل مقارنه مع مجموعه السيطرة. نستنتج من دراستنا هذه ارتباط تسمم الحمل خلال الربع الثالث من الحمل مع زيادة تركيز الحديد في دم الامهات المصابات بتسمم الحمل وهذه النسب المرتفعه قد تؤدي الى زيادة خطورة تسمم الحمل في النساء الحوامل.

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